






| Protein: | ITT1_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 464 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ITT1_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
1.0E-98 | [1..464] | [1..464] |
|
|
2.0E-63 | [7..459] | [10..462] |
|
|
1.0E-62 | [7..459] | [10..461] |
|
|
5.0E-60 | [8..460] | [16..425] |
|
|
1.0E-57 | [41..453] | [3..329] |
|
Region A: Residues: [1-77] |
1 11 21 31 41 51
| | | | | |
1 MALTQFENDL EILRDMYPEL EMKSVKVEEE GEFPQRINGK LLFKISLLAD VNIEFGEQHM 60
61 LLSNLSNECV EFTIYSC
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
|
Region A: Residues: [78-153] |
1 11 21 31 41 51
| | | | | |
1 HYPDIRRCVV MDIKSLWIST DEKKMLIDKA LRLVEETVDM SIEFADSFTS ILILIFGFLI 60
61 DDTAILLFPN GIRKCL
|
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.841 | 0.088 | regulation of translational termination | a.27.1 | Anticodon-binding domain of a subclass of class I aminoacyl-tRNA synthetases |
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.65442784325159 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| binding | 2.78710909602478 | bayes_pls_golite062009 |
| transcription regulator activity | 2.32056863527247 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91926431269551 | bayes_pls_golite062009 |
| DNA binding | 1.67694054164995 | bayes_pls_golite062009 |
| protein binding | 1.5975811408548 | bayes_pls_golite062009 |
| ligase activity | 1.36029325773279 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| transcription factor binding | 1.04179360284548 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| transcription factor activity | 0.942440775656356 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.260419630474309 | bayes_pls_golite062009 |
| transcription repressor activity | 0.251823232412941 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.120138679619734 | bayes_pls_golite062009 |
|
Region A: Residues: [154-251] |
1 11 21 31 41 51
| | | | | |
1 TQDQYDLFKQ ISEEATLQKV SRSNYHCCIC MEMEKGVRMI KLPCENANVE HYLCRGCAKS 60
61 YFTAMIQENR ISSVRCPQCE YKELKLEDFK SYKKMLKA
|
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.65442784325159 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| binding | 2.78710909602478 | bayes_pls_golite062009 |
| transcription regulator activity | 2.32056863527247 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91926431269551 | bayes_pls_golite062009 |
| DNA binding | 1.67694054164995 | bayes_pls_golite062009 |
| protein binding | 1.5975811408548 | bayes_pls_golite062009 |
| ligase activity | 1.36029325773279 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| transcription factor binding | 1.04179360284548 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| transcription factor activity | 0.942440775656356 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.260419630474309 | bayes_pls_golite062009 |
| transcription repressor activity | 0.251823232412941 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.120138679619734 | bayes_pls_golite062009 |
|
Region A: Residues: [252-338] |
1 11 21 31 41 51
| | | | | |
1 LFTPLIPVSF LKEVIDTELC ERYEKMFYNQ AATRLSKYCP YACVTCRRCD SWCTKEDLDD 60
61 AMIQCQKCHF VFCFDCLHAW HGYNNKC
|
| Detection Method: | |
| Confidence: | 18.920819 |
| Match: | PF01485 |
| Description: | IBR domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
| Term | Confidence | Notes |
| ubiquitin-protein ligase activity | 5.65442784325159 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 5.55686022186257 | bayes_pls_golite062009 |
| acid-amino acid ligase activity | 4.59153177011595 | bayes_pls_golite062009 |
| ligase activity, forming carbon-nitrogen bonds | 3.07217714843839 | bayes_pls_golite062009 |
| binding | 2.78710909602478 | bayes_pls_golite062009 |
| transcription regulator activity | 2.32056863527247 | bayes_pls_golite062009 |
| nucleic acid binding | 1.91926431269551 | bayes_pls_golite062009 |
| DNA binding | 1.67694054164995 | bayes_pls_golite062009 |
| protein binding | 1.5975811408548 | bayes_pls_golite062009 |
| ligase activity | 1.36029325773279 | bayes_pls_golite062009 |
| small conjugating protein-specific protease activity | 1.2126425713931 | bayes_pls_golite062009 |
| transcription factor binding | 1.04179360284548 | bayes_pls_golite062009 |
| ubiquitin-specific protease activity | 1.03469202541773 | bayes_pls_golite062009 |
| transcription factor activity | 0.942440775656356 | bayes_pls_golite062009 |
| cysteine-type peptidase activity | 0.50197530717959 | bayes_pls_golite062009 |
| ubiquitin thiolesterase activity | 0.265769062717221 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 0.260419630474309 | bayes_pls_golite062009 |
| transcription repressor activity | 0.251823232412941 | bayes_pls_golite062009 |
| catalytic activity | 0.14112008370434 | bayes_pls_golite062009 |
| transcription cofactor activity | 0.120138679619734 | bayes_pls_golite062009 |
|
Region A: Residues: [339-464] |
1 11 21 31 41 51
| | | | | |
1 GKKVSLSTDI IEEYLDDTVT SYERKRKLEA KYGRRVLELE VNDYLAEKML DLAIKKEGSN 60
61 LQRCPKCKVV VERSEGCNKM KCEVCGTLFC FICGVLLYPE DPYEHFREAY SGCYGRLFEG 120
121 MPGTET
|
| Detection Method: | |
| Confidence: | 2.075721 |
| Match: | PF01485 |
| Description: | IBR domain |
Shown below is our most confident prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.