| Protein: | HOP1_YEAST |
| Organism: | Saccharomyces cerevisiae S288c |
| Length: | 605 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for HOP1_YEAST.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..605] | [1..605] |
|
|
0.0 | [1..605] | [1..581] |
|
|
2.0E-82 | [1..302] | [1..281] |
|
|
2.0E-64 | [2..285] | [12..260] |
|
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2.0E-63 | [1..283] | [1..270] |
|
Region A: Residues: [1-297] |
1 11 21 31 41 51
| | | | | |
1 MSNKQLVKPK TETKTEITTE QSQKLLQTML TMSFGCLAFL RGLFPDDIFV DQRFVPEKVE 60
61 KNYNKQNTSQ NNSIKIKTLI RGKSAQADLL LDWLEKGVFK SIRLKCLKAL SLGIFLEDPT 120
121 DLLENYIFSF DYDEENNVNI NVNLSGNKKG SKNADPENET ISLLDSRRMV QQLMRRFIII 180
181 TQSLEPLPQK KFLTMRLMFN DNVDEDYQPE LFKDATFDKR ATLKVPTNLD NDAIDVGTLN 240
241 TKHHKVALSV LSAATSSMEK AGNTNFIRVD PFDLILQQQE ENKLEESVPT KPQNFVT
|
| Detection Method: |  |
| Confidence: | 44.0 |
| Match: | 1klqA_ |
| Description: | The spindle assembly checkpoint protein mad2 |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| binding | 2.13055115474904 | bayes_pls_golite062009 |
| protein binding | 0.818584450437447 | bayes_pls_golite062009 |
|
Region A: Residues: [298-362] |
1 11 21 31 41 51
| | | | | |
1 SQTTNVLGNL LNSSQASIQP TQFVSNNPVT GICSCECGLE VPKAATVLKT CKSCRKTLHG 60
61 ICYGN
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.828 | 0.118 | synaptonemal complex | d.58.17 | Metal-binding domain |
| View | Download | 0.721 | 0.118 | synaptonemal complex | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.758 | 0.118 | synaptonemal complex | d.52.1 | Alpha-lytic protease prodomain |
| View | Download | 0.720 | 0.118 | synaptonemal complex | d.58.17 | Metal-binding domain |
| View | Download | 0.649 | 0.118 | synaptonemal complex | d.58.10 | Acylphosphatase-like |
| View | Download | 0.591 | 0.118 | synaptonemal complex | d.52.3 | Prokaryotic type KH domain (KH-domain type II) |
| View | Download | 0.471 | 0.118 | synaptonemal complex | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.465 | 0.118 | synaptonemal complex | a.60.11 | Hypothetical protein YjbJ |
| View | Download | 0.461 | 0.118 | synaptonemal complex | d.58.23 | Probable ACP-binding domain of malonyl-CoA ACP transacylase |
| View | Download | 0.435 | 0.118 | synaptonemal complex | d.141.1 | Ribosomal protein L6 |
| View | Download | 0.401 | 0.118 | synaptonemal complex | d.58.4 | Dimeric alpha+beta barrel |
| View | Download | 0.396 | 0.118 | synaptonemal complex | d.74.5 | Hypothetical protein Yml108w |
| View | Download | 0.384 | 0.118 | synaptonemal complex | c.52.2 | tRNA splicing endonuclease, C-terminal domain |
| View | Download | 0.374 | 0.118 | synaptonemal complex | a.60.1 | SAM/Pointed domain |
| View | Download | 0.371 | 0.118 | synaptonemal complex | d.58.8 | Viral DNA-binding domain |
| View | Download | 0.358 | 0.118 | synaptonemal complex | d.45.1 | ClpS-like |
| View | Download | 0.345 | 0.118 | synaptonemal complex | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.309 | 0.118 | synaptonemal complex | d.58.24 | CheY-binding domain of CheA |
| View | Download | 0.296 | 0.118 | synaptonemal complex | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.295 | 0.118 | synaptonemal complex | d.58.35 | Pseudouridine synthase |
| View | Download | 0.292 | 0.118 | synaptonemal complex | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.287 | 0.118 | synaptonemal complex | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.271 | 0.118 | synaptonemal complex | d.57.1 | DNA damage-inducible protein DinI |
| View | Download | 0.266 | 0.118 | synaptonemal complex | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.266 | 0.118 | synaptonemal complex | d.58.18 | Regulatory domain in the aminoacid metabolism |
| View | Download | 0.263 | 0.118 | synaptonemal complex | d.58.11 | EF-G/eEF-2 domains III and V |
| View | Download | 0.260 | 0.118 | synaptonemal complex | d.58.5 | GlnB-like |
| View | Download | 0.258 | 0.118 | synaptonemal complex | d.58.44 | Multidrug efflux transporter AcrB pore domain; PN1, PN2, PC1 and PC2 subdomains |
| View | Download | 0.257 | 0.118 | synaptonemal complex | d.58.12 | eEF-1beta-like |
| View | Download | 0.255 | 0.118 | synaptonemal complex | d.94.1 | HPr-like |
| View | Download | 0.247 | 0.118 | synaptonemal complex | d.58.12 | eEF-1beta-like |
| View | Download | 0.243 | 0.118 | synaptonemal complex | d.58.13 | Anticodon-binding domain of PheRS |
| View | Download | 0.242 | 0.118 | synaptonemal complex | d.58.38 | Urease metallochaperone UreE, C-terminal domain |
| View | Download | 0.239 | 0.118 | synaptonemal complex | f.14.1 | Voltage-gated potassium channels |
| View | Download | 0.237 | 0.118 | synaptonemal complex | d.58.17 | Metal-binding domain |
| View | Download | 0.230 | 0.118 | synaptonemal complex | a.60.3 | C-terminal domain of RNA polymerase alpha subunit |
| View | Download | 0.229 | 0.118 | synaptonemal complex | d.58.49 | YajQ-like |
| View | Download | 0.223 | 0.118 | synaptonemal complex | a.163.1 | Crustacean CHH/MIH/GIH neurohormone |
| View | Download | 0.222 | 0.118 | synaptonemal complex | d.52.2 | GMP synthetase C-terminal dimerisation domain |
| View | Download | 0.218 | 0.118 | synaptonemal complex | d.58.5 | GlnB-like |
| View | Download | 0.216 | 0.118 | synaptonemal complex | a.60.1 | SAM/Pointed domain |
| View | Download | 0.214 | 0.118 | synaptonemal complex | d.58.40 | D-ribose-5-phosphate isomerase (RpiA), lid domain |
| View | Download | 0.208 | 0.118 | synaptonemal complex | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.208 | 0.118 | synaptonemal complex | d.109.1 | Actin depolymerizing proteins |
| View | Download | 0.206 | 0.118 | synaptonemal complex | d.58.1 | 4Fe-4S ferredoxins |
| View | Download | 0.201 | 0.118 | synaptonemal complex | d.52.5 | Probable GTPase Der, C-terminal domain |
| Term | Confidence | Notes |
| binding | 2.84147289283175 | bayes_pls_golite062009 |
| histone binding | 2.18177552065219 | bayes_pls_golite062009 |
| protein binding | 1.32925779020231 | bayes_pls_golite062009 |
| transcription regulator activity | 1.0641566670887 | bayes_pls_golite062009 |
| DNA binding | 0.971448192185972 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.967231932888801 | bayes_pls_golite062009 |
| chromatin binding | 0.880691867408093 | bayes_pls_golite062009 |
| nucleic acid binding | 0.853862782088463 | bayes_pls_golite062009 |
| histone acetyltransferase activity | 0.831882636066806 | bayes_pls_golite062009 |
| lysine N-acetyltransferase activity | 0.831882636066806 | bayes_pls_golite062009 |
| methylated histone residue binding | 0.635303636820801 | bayes_pls_golite062009 |
| transcription repressor activity | 0.592444465044507 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.326699327690106 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.290550172892431 | bayes_pls_golite062009 |
| DNA helicase activity | 0.290236218269237 | bayes_pls_golite062009 |
| transcription factor activity | 0.0935432513162235 | bayes_pls_golite062009 |
|
Region A: Residues: [363-605] |
1 11 21 31 41 51
| | | | | |
1 FLHSSIEKCF TCIFGPSLDT KWSKFQDLMM IRKVFRFLVR KKKGFPASIT ELIDSFINVE 60
61 DQNNEVKERV AFALFVFFLD ETLCLDNGGK PSQTIRYVTS SVLVDVKGIV IPNTRKQLNV 120
121 NHEYKWHFTT SSPKAESFYQ EVLPNSRKQV ESWLQDITNL RKVYSEALSP SSTLQELDLN 180
181 SSLPTQDPII SGQKRRRYDL DEYLEEDKSS VVNDTIKAKD FDESVPAKIR KISVSKKTLK 240
241 SNW
|
| Detection Method: | |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.475 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.285 | b.34.4 | Electron transport accessory proteins |
| View | Download | 0.475 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.463 | f.13.1 | Family A G protein-coupled receptor-like |
| View | Download | 0.285 | b.34.4 | Electron transport accessory proteins |
