YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Structure Prediction Details

Protein: TFB4_YEAST
Organism: Saccharomyces cerevisiae S288c
Length: 338 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



[What does the above image mean?]


[Show Ginzu Version Information]


Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for TFB4_YEAST.

Description E-value Query
Range		 Subject
Range
gi|190407994 - gi|190407994|gb|EDV11259.1| RNA polymerase II transcription factor B subunit 4 [Saccharomyces cerevi...
TFB4_YEAST - RNA polymerase II transcription factor B subunit 4 OS=Saccharomyces cerevisiae (strain ATCC 204508 /...
TFB4 - Subunit of TFIIH complex, involved in transcription initiation, similar to 34 kDa subunit of human T...
 0.0 [1..338] [1..338]
GTF2H3 - general transcription factor IIH, polypeptide 3, 34kDa
gi|208966364 - gi|208966364|dbj|BAG73196.1| general transcription factor IIH, polypeptide 3, 34kDa [synthetic const...
 0.0 [20..334] [5..302]
gi|7507776 - gi|7507776|pir||T16867 probable cytochrome P450 T13C5.1 [similarity] - Caenorhabditis elegans
 0.0 [20..334] [5..302]
TFB4_ARATH - RNA polymerase II transcription factor B subunit 4 OS=Arabidopsis thaliana GN=TFB4 PE=2 SV=1
 1.0E-86 [12..314] [3..282]
gi|2257568 - gi|2257568|dbj|BAA21460.1| basic transcription factor 2.35KD subunit [Schizosaccharomyces pombe]
 3.0E-86 [17..318] [17..292]
tfb4 - transcription factor TFIIH complex subunit Tfb4
TFB4_SCHPO - RNA polymerase II transcription factor B subunit 4 OS=Schizosaccharomyces pombe (strain 972 / ATCC 2...
 2.0E-85 [17..319] [17..293]
Tfb4-PA - The gene Tfb4 is referred to in FlyBase by the symbol Dmel\Tfb4 (CG5041, FBgn0031309). It is a prote...
 9.0E-83 [14..312] [7..279]

Back

Predicted Domain #1
Region A:
Residues: [1-338] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDAISDPTFK HARSRKQVTE ESPSLLTVII EIAPKLWTTF DEEGNEKGSI IKVLEALIVF  60
   61 LNAHLAFNSA NKVAVIAAYS QGIKYLYPES TSALKASESE NKTRSDLKII NSDMYRRFRN 120
  121 VDETLVEEIY KLFELEKKQI EQNSQRSTLA GAMSAGLTYV NRISKESVTT SLKSRLLVLT 180
  181 CGSGSSKDEI FQYIPIMNCI FSATKMKCPI DVVKIGGSKE STFLQQTTDA TNGVYLHVES 240
  241 TEGLIQYLAT AMFIDPSLRP IIVKPNHGSV DFRTSCYLTG RVVAVGFICS VCLCVLSIIP 300
  301 PGNKCPACDS QFDEHVIAKL KRKPVVPRLK AKKKVTKP

[Run NCBI BLAST on this sequence.]

Detection Method: Pfam
Confidence: 188.552842
Match: PF03850
Description: Transcription factor Tfb4

Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.

Found no structure predictions for this domain.

Predicted functions:

Term Confidence Notes
binding 2.68315152218267 bayes_pls_golite062009
nucleic acid binding 2.10023916482665 bayes_pls_golite062009
DNA binding 1.9295508897092 bayes_pls_golite062009
protein complex binding 1.65763332955233 bayes_pls_golite062009
protein binding 1.42792331963866 bayes_pls_golite062009
hydrolase activity 0.589248272940562 bayes_pls_golite062009
structure-specific DNA binding 0.446181458443121 bayes_pls_golite062009
protein dimerization activity 0.244402438311177 bayes_pls_golite062009
protein heterodimerization activity 0.114607758890868 bayes_pls_golite062009
catalytic activity 0.0380261580236634 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [240-338] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 STEGLIQYLA TAMFIDPSLR PIIVKPNHGS VDFRTSCYLT GRVVAVGFIC SVCLCVLSII  60
   61 PPGNKCPACD SQFDEHVIAK LKRKPVVPRL KAKKKVTKP

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 0.954
Match: 2ozyA
Description: No description for 2ozyA was found.
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle