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Protein Overview: tfb4

General Information:
Name(s) found: tfb4 / SPBC30B4.07c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • transcription factor TFIIH complex subunit Tfb4 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 297 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    core TFIIH complex [IEA]
    cytosol [IDALink to PubMed article]
    holo TFIIH complex [ISSLink to PubMed article]
    Biological Process: nucleotide-excision repair [ISS]
    regulation of transcription, DNA-dependent [IEA]
    transcription initiation from RNA polymerase II promoter [ISSLink to PubMed article]
    Molecular Function: zinc ion binding [IEA]
    general RNA polymerase II transcription factor activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDEFQTLKQN ASWDISEDAN DTPSLLVVIL DANPASWYSL SKKVPVSKVL ADITVFLNAH  60
   61 LAFHHDNRVA VLASHSDKVE YLYPSIAPEQ KVAEVDPTKE ANTYRKFREV DDLVLSGMKR 120
  121 LMSSTDKVSR KTMISGALSR ALAYINQVQN KNTLRSRILI FSLTGDVALQ YIPTMNCIFC 180
  181 AQKKNIPINV CNIEGGTLFL EQAADATGGI YLKVDNPKGL LQYLMMSLFP DQNLRKHLNT 240
  241 PNQANVDFRA TCFCHKKVLD IGFVCSVCLS IFCEPRVHCS TCHTKFTVEP MSKKLHT

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..297] FFAS03 2.38 A domain of Factor B

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • binding
    		•  2.68315152218267 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.10023916482665 bayes_pls_golite062009
  • DNA binding
    		•  1.9295508897092 bayes_pls_golite062009
  • protein complex binding
    		•  1.65763332955233 bayes_pls_golite062009
  • protein binding
    		•  1.42792331963866 bayes_pls_golite062009
  • hydrolase activity
    		•  0.589248272940562 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.446181458443121 bayes_pls_golite062009
  • protein dimerization activity
    		•  0.244402438311177 bayes_pls_golite062009
  • protein heterodimerization activity
    		•  0.114607758890868 bayes_pls_golite062009
  • catalytic activity
    		•  0.0380261580236634 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle