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View Structure Prediction Details

Protein: gi|1209511
Organism: Plasmodium falciparum
Length: 171 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|1209511.

Description E-value Query
Range		 Subject
Range
gi|50301248 - gi|50301248|gb|AAT73777.1| TRIM5/cyclophilin A fusion protein [Aotus trivirgatus]
 273.0 [0..4] [171..313]
gi|255538956, gi... - gi|255538956|ref|XP_002510543.1| cyclophilin, putative [Ricinus communis], gi|223551244|gb|EEF52730....
 257.0 [0..1] [171..1]
PPID_NEUCR - 41 kDa peptidyl-prolyl cis-trans isomerase OS=Neurospora crassa (strain ATCC 24698 / 74-OR23-1A / CB...
PPID_NEUCR - 41 kDa peptidyl-prolyl cis-trans isomerase OS=Neurospora crassa GN=cyp-41 PE=2 SV=1
 255.0 [0..3] [171..10]
gi|94381275, gi|... - gi|94381275|ref|XP_918992.2| PREDICTED: similar to Peptidyl-prolyl cis-trans isomerase A (PPIase) (R...
 252.0 [0..4] [171..75]
gi|21886603 - gi|21886603|emb|CAC84116.1| peptidylprolyl isomerase (cyclophilin) [Betula pendula]
 251.0 [0..1] [171..1]
gi|91094253 - gi|91094253|ref|XP_969008.1| PREDICTED: similar to CG4554-PA [Tribolium castaneum]
 251.0 [0..3] [171..139]
PPIA - peptidylprolyl isomerase A (cyclophilin A)
PPIA_CERAE - (P62938) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) ...
PPIA_PAPAN - (P62941) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) ...
PPIA_MACMU - (P62940) Peptidyl-prolyl cis-trans isomerase A (EC 5.2.1.8) (PPIase A) (Rotamase A) (Cyclophilin A) ...
 250.0 [0..4] [171..2]

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Predicted Domain #1
Region A:
Residues: [1-171] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSKRSKVFFD ISIDNSNAGR IIFELFSDIT PRTCENFRAL CTGEKIGSRG KNLHYKNSIF  60
   61 HRIIPQFMCQ GGDITNGNGS GGESIYGRSF TDENFNMKHD QPGLLSMANA GPNTNSSQFF 120
  121 ITLVPCPWLD GKHVVFGKVI EGMNVVREME KEGAKSGYVK RSVVITDCGE L

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 63.522879
Match: 1qngA
Description: Cyclophilin (eukaryotic)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
protein deacetylase activity 4.3775483906311 bayes_pls_golite062009
histone deacetylase activity 4.29026678196473 bayes_pls_golite062009
peptidyl-prolyl cis-trans isomerase activity 3.73853378771688 bayes_pls_golite062009
cis-trans isomerase activity 3.66963215732405 bayes_pls_golite062009
deacetylase activity 3.49940864924766 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides 3.01511519120932 bayes_pls_golite062009
RNA binding 2.94609837984526 bayes_pls_golite062009
isomerase activity 1.96529188741504 bayes_pls_golite062009
binding 1.46018233647024 bayes_pls_golite062009
mRNA binding 1.45537055700871 bayes_pls_golite062009
unfolded protein binding 1.38124355054041 bayes_pls_golite062009
nucleic acid binding 0.939772862764466 bayes_pls_golite062009
catalytic activity 0.748655649755714 bayes_pls_golite062009
hydrolase activity 0.493806105600863 bayes_pls_golite062009
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds 0.408539130322443 bayes_pls_golite062009
drug binding 0.36339132904137 bayes_pls_golite062009
ubiquitin-protein ligase activity 0.322244688184474 bayes_pls_golite062009
small conjugating protein ligase activity 0.286133802341887 bayes_pls_golite062009
histone binding 0.268719695649015 bayes_pls_golite062009
protein binding 0.130251391659493 bayes_pls_golite062009
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle