YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|7494255
Organism:	Plasmodium falciparum
Length:	225 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|7494255.

Description	E-value	Query Range	Subject Range
gi\|55666783 - gi\|55666783\|ref\|XP_520655.1\| PREDICTED: proteasome 26S non-ATPase subunit 9 [Pan troglodytes]	161.0	[0..1]	[223..18]
gi\|109099062 - gi\|109099062\|ref\|XP_001096532.1\| PREDICTED: proteasome (prosome, macropain) 26S subunit, non-ATPase,...	161.0	[0..1]	[223..18]
PSMD9 - proteasome (prosome, macropain) 26S subunit, non-ATPase, 9	160.0	[0..1]	[223..18]
gi\|60653051, gi\|... - gi\|60653053\|gb\|AAX29221.1\| proteasome 26S subunit 9 [synthetic construct], gi\|60653051\|gb\|AAX29220.1...	160.0	[0..1]	[223..18]
gi\|11340794\|emb\|... - unnamed protein product [Rattus sp.] PSMD9_RAT - 26S proteasome non-ATPase regulatory subunit 9 OS=Rattus norvegicus GN=Psmd9 PE=1 SV=1	156.0	[0..3]	[223..20]
gi\|73994527 - gi\|73994527\|ref\|XP_534665.2\| PREDICTED: similar to 26S proteasome non-ATPase regulatory subunit 9 (2...	154.0	[0..1]	[223..18]
gi\|74212236, gi\|... - gi\|74212236\|dbj\|BAE40276.1\| unnamed protein product [Mus musculus], gi\|148687699\|gb\|EDL19646.1\| prot...	153.0	[0..3]	[223..20]
PSMD9_BOVIN - 26S proteasome non-ATPase regulatory subunit 9 OS=Bos taurus GN=PSMD9 PE=1 SV=1	151.0	[0..1]	[223..18]

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Predicted Domain #1

Region A:
Residues: [1-225]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MNLEEFNELV KKREDIENEL KEHMDFLERP ENKNVGMKGN LIDSEGFPRN DIDIYSIRVA  60
   61 RNKIICLKND YIDINKKLEE YIHKVHSTHP VIRVERKKNI NNDLLNTPQQ ITKEEDIKNA 120
  121 KKNVFAIIDE VIENSPSHKS GLKINDQIFQ FGNIIKTNEN KKENEHNHPL NVELIKDIAK 180
  181 YMKTQPKQIV VKILREENIF FFHIIPEQTH NGLYLGCHLS PFDSS

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	31.0
Match:	1ky9A
Description:	Protease Do (DegP, HtrA), C-terminal domains; Protease Do (DegP, HtrA), catalytic domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
peptidase activity	4.00482245922158	bayes_pls_golite062009
peptidase activity, acting on L-amino acid peptides	3.80641317919152	bayes_pls_golite062009
endopeptidase activity	3.69721977392816	bayes_pls_golite062009
protein binding	3.40921081688513	bayes_pls_golite062009
binding	3.2595117613307	bayes_pls_golite062009
hydrolase activity	2.69939003844937	bayes_pls_golite062009
transcription regulator activity	2.16834620509051	bayes_pls_golite062009
transcription activator activity	1.37255187012662	bayes_pls_golite062009
transporter activity	0.666562078558936	bayes_pls_golite062009
transmembrane transporter activity	0.510205657363692	bayes_pls_golite062009
enzyme binding	0.46071739042312	bayes_pls_golite062009
ubiquitin-protein ligase activity	0.342817187733892	bayes_pls_golite062009
small conjugating protein ligase activity	0.299572882681276	bayes_pls_golite062009
structural molecule activity	0.153277808949873	bayes_pls_golite062009
substrate-specific transporter activity	0.141613198202921	bayes_pls_golite062009
PDZ domain binding	0.0604467745298803	bayes_pls_golite062009
transcription factor binding	0.0283953080227368	bayes_pls_golite062009
cytoskeletal protein binding	0.0187659836234897	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: