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View Structure Prediction Details

Protein: ALKR1_ARATH
Organism: Arabidopsis thaliana
Length: 344 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for ALKR1_ARATH.

Description E-value Query
Range
Subject
Range
ALKR4_ARATH - Probable aldo-keto reductase 4 OS=Arabidopsis thaliana GN=At1g60710 PE=2 SV=1
375.0 [0..1] [344..1]

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Predicted Domain #1
Region A:
Residues: [1-344]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAAASGVRRI KLGSQGLEVS AQGLGCMGLS IFDGTTKVET DLIALIHHAI NSGITLLDTS  60
   61 DIYGPETNEL LLGQALKDGM REKVELATKF GLLLKDQKLG YRGDPAYVRA ACEASLRRLG 120
  121 VSCIDLYYQH RIDTTVPIEV TIGELKKLVE EGKIKYIGLS EACASTIRRA HAVHPLTAVQ 180
  181 LEWSLWSRDV EEDIIPTCRE LGIGIVAYSP LGLGFFAAGP KFIESMDNGD YRKGLPRFQQ 240
  241 ENLDHNKILY EKVNAMAEKK SCTPAQLALA WVHHQGNDVC PIPGTSKIKN LNQNIGALSV 300
  301 KLSIEEMAEL DAMGHPDSVK GERSATYIVT YKNSETPPLS SWTS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 84.522879
Match: 1pyfA
Description: Structure of NADPH-dependent family 11 aldo-keto reductase AKR11A(apo)
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
potassium channel activity 7.51963276589303 bayes_pls_golite062009
voltage-gated potassium channel activity 7.40239094355354 bayes_pls_golite062009
voltage-gated cation channel activity 6.67507110634301 bayes_pls_golite062009
metal ion transmembrane transporter activity 6.588881463055 bayes_pls_golite062009
voltage-gated ion channel activity 6.52286930358188 bayes_pls_golite062009
voltage-gated channel activity 6.50716590143831 bayes_pls_golite062009
cation channel activity 5.72172645555113 bayes_pls_golite062009
ion channel activity 5.15119282480682 bayes_pls_golite062009
passive transmembrane transporter activity 5.07214658557001 bayes_pls_golite062009
channel activity 5.07214658557001 bayes_pls_golite062009
substrate-specific channel activity 5.02503292701043 bayes_pls_golite062009
gated channel activity 4.92848832197692 bayes_pls_golite062009
L-glucuronate reductase activity 4.06568552614053 bayes_pls_golite062009
pyridoxine 4-dehydrogenase activity 3.25535446462297 bayes_pls_golite062009
ion transmembrane transporter activity 2.63772951680109 bayes_pls_golite062009
cation transmembrane transporter activity 2.58068601897668 bayes_pls_golite062009
aldo-keto reductase activity 2.57303336304449 bayes_pls_golite062009
aryl-alcohol dehydrogenase activity 2.5168190536972 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 2.46488926936937 bayes_pls_golite062009
catalytic activity 1.68179794468736 bayes_pls_golite062009
transporter activity 1.24767072239634 bayes_pls_golite062009
oxidoreductase activity 1.22645031212774 bayes_pls_golite062009
aldehyde reductase activity 1.16639404121425 bayes_pls_golite062009
binding 1.15657176144267 bayes_pls_golite062009
transmembrane transporter activity 1.03420335553507 bayes_pls_golite062009
potassium channel regulator activity 1.03017249802223 bayes_pls_golite062009
oxidoreductase activity, acting on CH-OH group of donors 0.868027162240181 bayes_pls_golite062009
oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor 0.86591084281532 bayes_pls_golite062009
substrate-specific transporter activity 0.783004917746429 bayes_pls_golite062009
protein binding 0.220529867719707 bayes_pls_golite062009
3-alpha-hydroxysteroid dehydrogenase (B-specific) activity 0.207008954325429 bayes_pls_golite062009
trans-1,2-dihydrobenzene-1,2-diol dehydrogenase activity 0.207008954325429 bayes_pls_golite062009
0.139676323362391 bayes_pls_golite062009
channel regulator activity 0.12154513851913 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
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