| Protein: | gi|40788228 |
| Organism: | Homo sapiens |
| Length: | 794 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|40788228.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [41..794] | [119..872] |
|
|
0.0 | [66..794] | [1..729] |
|
|
0.0 | [17..793] | [1..781] |
|
|
0.0 | [66..793] | [1..730] |
|
Region A: Residues: [1-97] |
1 11 21 31 41 51
| | | | | |
1 WPQPRRRAPA AAAAQPGPAA APQPCSPAAP AAPSPARTAP GGGPQRGHKD PRRRLSADRS 60
61 YLKSIMSFGR DMELEHFDER DKAQRYSRGS RVNGLPS
|
| Detection Method: |  |
Shown below are all of our de novo (Rosetta) predictions for this domain.
Click here to view only most confident match.
| MCM Score |
SCOP Match |
SCOP Description | ||
| View | Download | 0.504 | a.26.1 | 4-helical cytokines |
| View | Download | 0.481 | d.14.1 | Ribosomal protein S5 domain 2-like |
| View | Download | 0.428 | a.118.8 | TPR-like |
| View | Download | 0.408 | a.43.1 | Met repressor-like |
| View | Download | 0.324 | a.118.8 | TPR-like |
|
Region A: Residues: [98-276] |
1 11 21 31 41 51
| | | | | |
1 PTHSAHCSFY RTRTLQTLSS EKKAKKVRFY RNGDRYFKGI VYAISPDRFR SFEALLADLT 60
61 RTLSDNVNLP QGVRTIYTID GLKKISSLDQ LVEGESYVCG SIEPFKKLEY TKNVNPNWSV 120
121 NVKTTSASRA VSSLATAKGS PSEVRENKDF IRPKLVTIIR SGVKPRKAVR ILLNKKTAH
|
| Detection Method: | |
| Confidence: | 4.52 |
| Match: | 1uf0A |
| Description: | Solution structure of the N-terminal DCX domain of human doublecortin-like kinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| tubulin binding | 3.90289085404019 | bayes_pls_golite062009 |
| microtubule binding | 3.8893078535855 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 3.0030780125289 | bayes_pls_golite062009 |
| binding | 1.95644573063384 | bayes_pls_golite062009 |
| protein binding | 0.477323490762673 | bayes_pls_golite062009 |
|
Region A: Residues: [277-716] |
1 11 21 31 41 51
| | | | | |
1 SFEQVLTDIT DAIKLDSGVV KRLYTLDGKQ VMCLQDFFGD DDIFIACGPE KFRYQDDFLL 60
61 DESECRVVKS TSYTKIASSS RRSTTKSPGP SRRSKSPAST SSVNGTPGSQ LSTPRSGKSP 120
121 SPSPTSPGSL RKQRSSQHGG SSTSLASTKV CSSMDENDGP GEEVSEEGFQ IPATITERYK 180
181 VGRTIGDGNF AVVKECVERS TAREYALKII KKSKCRGKEH MIQNEVSILR RVKHPNIVLL 240
241 IEEMDVPTEL YLVMELVKGG DLFDAITSTN KYTERDASGM LYNLASAIKY LHSLNIVHRD 300
301 IKPENLLVYE HQDGSKSLKL GDFGLATIVD GPLYTVCGTP TYVAPEIIAE TGYGLKVDIW 360
361 AAGVITYILL CGFPPFRGSG DDQEVLFDQI LMGQVDFPSP YWDNVSDSAK ELITMMLLVD 420
421 VDQRFSAVQV LEHPWVNDDG
|
| Detection Method: | |
| Confidence: | 49.69897 |
| Match: | 1k9aA |
| Description: | Carboxyl-terminal src kinase (csk) |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 5.04467222534257 | bayes_pls_golite062009 |
| kinase activity | 4.85903980916957 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.63692708178478 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| calmodulin-dependent protein kinase activity | 4.31938467136214 | bayes_pls_golite062009 |
| transferase activity | 3.26787750561728 | bayes_pls_golite062009 |
| molecular transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| signal transducer activity | 2.85730457922199 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| telethonin binding | 2.81155575828766 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.28919522845509 | bayes_pls_golite062009 |
| tubulin binding | 2.18641675163967 | bayes_pls_golite062009 |
| receptor activity | 2.14074739723463 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 2.12615078788254 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| alpha-actinin binding | 1.92962505218614 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 1.90879495821405 | bayes_pls_golite062009 |
| microtubule binding | 1.88110801192607 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 1.7769021678395 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 1.4571078357189 | bayes_pls_golite062009 |
| actin binding | 1.33479685165255 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.33329180203433 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.33329180203433 | bayes_pls_golite062009 |
| gamma-tubulin binding | 1.28511591054866 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| insulin receptor activity | 0.974517002259609 | bayes_pls_golite062009 |
| transmembrane-ephrin receptor activity | 0.971682315034679 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.880236579821909 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| activin receptor activity | 0.811117252475389 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| structural constituent of cytoskeleton | 0.612883428421652 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| activin binding | 0.465961724597021 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| PTB domain binding | 0.384625387464921 | bayes_pls_golite062009 |
| kinase binding | 0.26752427107238 | bayes_pls_golite062009 |
| actin filament binding | 0.2403700250846 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| activin receptor activity, type I | 0.117759584117941 | bayes_pls_golite062009 |
| MAP kinase activity | 0.08504542461349 | bayes_pls_golite062009 |
| growth factor binding | 0.0526340287295695 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.00836512390788968 | bayes_pls_golite062009 |
| protein kinase binding | 0.00674998152095019 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.0040394359628233 | bayes_pls_golite062009 |
|
Region A: Residues: [717-794] |
1 11 21 31 41 51
| | | | | |
1 LPENEHQLSV AGKIKKHFNT GPKPNSTAAG VSVIALDHGF TIKRSGSLDY YQQPGMYWIR 60
61 PPLLIRRGRF SDEDATRM
|
| Detection Method: | |
| Confidence: | 74.0 |
| Match: | 2jc6A |
| Description: | No description for 2jc6A was found. |
