| Protein: | WNK8_ARATH |
| Organism: | Arabidopsis thaliana |
| Length: | 563 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for WNK8_ARATH.
| Description | E-value | Query Range |
Subject Range |
|
|
371.0 | [0..10] | [563..55] |
|
Region A: Residues: [1-306] |
1 11 21 31 41 51
| | | | | |
1 MASGSGFLGQ ISSMEEADFA EKDPSGRYIR YDDVLGRGAF KTVYKAFDEV DGIEVAWNLV 60
61 SIEDVMQMPG QLERLYSEVH LLKALKHENI IKLFYSWVDE KNKTINMITE LFTSGSLRVY 120
121 RKKHRKVDPK AIKNWARQIL KGLNYLHSQN PPVIHRDLKC DNIFVNGNTG EVKIGDLGLA 180
181 TVLQQPTARS VIGTPEFMAP ELYEEEYNEL VDIYSFGMCM LEMVTCEYPY NECRNQAQIY 240
241 KKVTSNIKPQ SLGKVDDPQV RQFIEKCLLP ASSRPTALEL SKDPFLARDG GKDSALLASS 300
301 STSSKY
|
| Detection Method: |  |
| Confidence: | 59.522879 |
| Match: | 1t4hA |
| Description: | Crystal structure of the kinase domain of WNK1, a kinase that causes a hereditary form of hypertension |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 1.3898059094397 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.38496328649031 | bayes_pls_golite062009 |
| receptor signaling protein activity | 1.27291233344322 | bayes_pls_golite062009 |
| protein binding | 1.22565748038754 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.499492353295369 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 0.35402045013148 | bayes_pls_golite062009 |
| signal transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| molecular transducer activity | 0.270054246024761 | bayes_pls_golite062009 |
| MAP kinase activity | 0.26024936404169 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 0.0556163711947139 | bayes_pls_golite062009 |
| transmembrane receptor activity | 0.00652065412910241 | bayes_pls_golite062009 |
|
Region A: Residues: [307-445] |
1 11 21 31 41 51
| | | | | |
1 VRPPQLEHLP MDVDHNENKS VSSNEDYPWS QTIELQRIAE NKEFRLRGER SDDVTASMVL 60
61 RIADPSGKCR IVHFAFYLES DTATAIAEEM VEELHLTSQE VVVIADMIDD FIMQLLSDRT 120
121 SSHHNQNSPR LTHEDHEAA
|
| Detection Method: | |
| Confidence: | 2.21 |
| Match: | 2v3sA |
| Description: | No description for 2v3sA was found. |
|
Region A: Residues: [446-563] |
1 11 21 31 41 51
| | | | | |
1 NQQTVNSKDE EAAGQSMKSD ISADYYFPYS ANDGNAAMEA GRDAESMSSY LDSCSMMSTI 60
61 YNLSISDNDY PEDLKTELNL IESQFNQSFQ DLLKLKEDAI ENAKRKWITK KQKAVNIS
|
| Detection Method: | |
Shown below is our most confident de novo (Rosetta) prediction for this domain.
Click here to view all matches.
Found no confident structure predictions for this domain.
