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View Structure Prediction Details

Protein: gi|208966756
Organism: synthetic construct
Length: 309 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|208966756.

Description E-value Query
Range
Subject
Range
gi|61371458, gi|... - gi|61371458|gb|AAX43671.1| menage a trois 1 [synthetic construct], gi|61371451|gb|AAX43670.1| menage...
6.0E-48 [1..309] [1..309]
gi|57090199 - gi|57090199|ref|XP_537469.1| PREDICTED: similar to CDK-activating kinase assembly factor MAT1 (RING ...
3.0E-47 [1..309] [1..309]
gi|157427944, gi... - gi|74356350|gb|AAI04523.1| MNAT1 protein [Bos taurus], gi|157427944|ref|NP_001098879.1| menage a tro...
6.0E-47 [1..309] [1..309]
MAT1_MOUSE - CDK-activating kinase assembly factor MAT1 OS=Mus musculus GN=Mnat1 PE=1 SV=2
1.0E-45 [1..308] [1..308]
gi|23618897, gi|... - gi|50925437|gb|AAH78712.1| Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis) [Ratt...
1.0E-45 [1..308] [1..308]
gi|62858507, gi|... - gi|89272861|emb|CAJ82156.1| menage a trois 1 (CAK assembly factor) [Xenopus tropicalis], gi|62858507...
3.0E-42 [1..308] [1..308]
MAT1_XENLA - CDK-activating kinase assembly factor MAT1 OS=Xenopus laevis GN=mnat1 PE=2 SV=1
gi|2134192 - gi|2134192|pir||S60120 RING finger protein chain MAT1 - clawed frog
5.0E-41 [1..307] [1..307]
gi|20151823 - gi|20151823|gb|AAM11271.1| RH31013p [Drosophila melanogaster]
2.0E-38 [1..306] [1..310]

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Predicted Domain #1
Region A:
Residues: [1-81]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MDDQGCPRCK TTKYRNPSLK LMVNVCGHTL CESCVDLLFV RGAGNCPECG TPLRKSNFRV  60
   61 QLFEDPTVDK EVEIRKKVLK I

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1g25A
Description: TFIIH Mat1 subunit
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 6.51043144330453 bayes_pls_golite062009
small conjugating protein ligase activity 3.14238164427954 bayes_pls_golite062009
ubiquitin-protein ligase activity 3.12673603940339 bayes_pls_golite062009
binding 2.78710909602478 bayes_pls_golite062009
transcription regulator activity 2.72498741013971 bayes_pls_golite062009
protein binding 2.64803540957326 bayes_pls_golite062009
nucleic acid binding 2.32387297115017 bayes_pls_golite062009
acid-amino acid ligase activity 2.10988747259202 bayes_pls_golite062009
DNA binding 2.00904221080834 bayes_pls_golite062009
transcription repressor activity 1.98209395225978 bayes_pls_golite062009
transcription activator activity 1.45530270292081 bayes_pls_golite062009
transcription factor activity 1.22579085356684 bayes_pls_golite062009
transcription factor binding 1.11842175076436 bayes_pls_golite062009
sequence-specific DNA binding 0.926364718530146 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.90321253993065 bayes_pls_golite062009
hydrolase activity 0.52386813728704 bayes_pls_golite062009
transcription corepressor activity 0.384990496120483 bayes_pls_golite062009
ligase activity 0.34187399168736 bayes_pls_golite062009
transcription coactivator activity 0.255669498391574 bayes_pls_golite062009
transcription cofactor activity 0.233838999434784 bayes_pls_golite062009
catalytic activity 0.14112008370434 bayes_pls_golite062009
enzyme binding 0.104373352314595 bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds 0.024993043379745 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [82-309]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 YNKREEDFPS LREYNDFLEE VEEIVFNLTN NVDLDNTKKK MEIYQKENKD VIQKNKLKLT  60
   61 REQEELEEAL EVERQENEQR RLFIQKEEQL QQILKRKNKQ AFLDELESSD LPVALLLAQH 120
  121 KDRSTQLEMQ LEKPKPVKPV TFSTGIKMGQ HISLAPIHKL EEALYEYQPL QIETYGPHVP 180
  181 ELEMLGRLGY LNHVRAASPQ DLAGGYTSSL ACHRALQDAF SGLFWQPS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 5.39794
Match: 2i1jA
Description: No description for 2i1jA was found.

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