From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.689866981797] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
ENT5 |
|
|
|
VPS51 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
cytoplasmic vesicle part | 3.744E-5 | 2 | 39 | 2 | 6292 |
cytoplasmic vesicle | 2.8654E-4 | 2 | 107 | 2 | 6292 |
membrane-bounded vesicle | 2.8654E-4 | 2 | 107 | 2 | 6292 |
cytoplasmic membrane-bounded vesicle | 2.8654E-4 | 2 | 107 | 2 | 6292 |
vesicle | 3.0291E-4 | 2 | 110 | 2 | 6292 |
GARP complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
clathrin vesicle coat | 4.4455E-3 | 2 | 14 | 1 | 6292 |
clathrin coat | 4.4455E-3 | 2 | 14 | 1 | 6292 |
clathrin coated vesicle membrane | 4.7627E-3 | 2 | 15 | 1 | 6292 |
clathrin-coated vesicle | 9.8303E-3 | 2 | 31 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
endosome transport | 6.6999E-5 | 2 | 52 | 2 | 6292 |
protein targeting | 1.3892E-3 | 2 | 235 | 2 | 6292 |
intracellular protein transport | 1.6363E-3 | 2 | 255 | 2 | 6292 |
protein transport | 1.8213E-3 | 2 | 269 | 2 | 6292 |
establishment of protein localization | 1.8485E-3 | 2 | 271 | 2 | 6292 |
cellular protein localization | 1.8898E-3 | 2 | 274 | 2 | 6292 |
cellular macromolecule localization | 2.0305E-3 | 2 | 284 | 2 | 6292 |
protein localization | 2.3118E-3 | 2 | 303 | 2 | 6292 |
vesicle-mediated transport | 2.9119E-3 | 2 | 340 | 2 | 6292 |
budding cell apical bud growth | 3.1764E-3 | 2 | 10 | 1 | 6292 |
Golgi to endosome transport | 3.4937E-3 | 2 | 11 | 1 | 6292 |
macromolecule localization | 3.9717E-3 | 2 | 397 | 2 | 6292 |
retrograde transport, endosome to Golgi | 6.0308E-3 | 2 | 19 | 1 | 6292 |
intracellular transport | 7.7118E-3 | 2 | 553 | 2 | 6292 |
establishment of localization in cell | 9.0494E-3 | 2 | 599 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
clathrin binding | 3.4937E-3 | 2 | 11 | 1 | 6292 |
protein binding | 9.4468E-3 | 2 | 612 | 2 | 6292 |