From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.038] [SVM Score: 0.696164537722] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
endoplasmic reticulum membrane | 4.4352E-4 | 2 | 133 | 2 | 6292 |
endoplasmic reticulum part | 5.6464E-4 | 2 | 150 | 2 | 6292 |
subsynaptic reticulum | 5.6464E-4 | 2 | 150 | 2 | 6292 |
extrinsic to endoplasmic reticulum membrane | 6.3568E-4 | 2 | 2 | 1 | 6292 |
palmitoyltransferase complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
nuclear membrane-endoplasmic reticulum network | 1.3539E-3 | 2 | 232 | 2 | 6292 |
glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex | 2.5415E-3 | 2 | 8 | 1 | 6292 |
endoplasmic reticulum | 3.3381E-3 | 2 | 364 | 2 | 6292 |
extrinsic to organelle membrane | 3.811E-3 | 2 | 12 | 1 | 6292 |
endomembrane system | 3.9918E-3 | 2 | 398 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
Ras protein signal transduction | 4.1432E-5 | 2 | 41 | 2 | 6292 |
protein amino acid lipidation | 6.6999E-5 | 2 | 52 | 2 | 6292 |
lipoprotein metabolic process | 6.6999E-5 | 2 | 52 | 2 | 6292 |
lipoprotein biosynthetic process | 6.6999E-5 | 2 | 52 | 2 | 6292 |
small GTPase mediated signal transduction | 1.0186E-4 | 2 | 64 | 2 | 6292 |
intracellular signal transduction | 3.312E-4 | 2 | 115 | 2 | 6292 |
intracellular signaling pathway | 5.2022E-4 | 2 | 144 | 2 | 6292 |
signaling pathway | 8.5067E-4 | 2 | 184 | 2 | 6292 |
signal transduction | 1.1516E-3 | 2 | 214 | 2 | 6292 |
signal transmission | 1.1841E-3 | 2 | 217 | 2 | 6292 |
signaling process | 1.1841E-3 | 2 | 217 | 2 | 6292 |
signaling | 1.598E-3 | 2 | 252 | 2 | 6292 |
protein palmitoylation | 2.5415E-3 | 2 | 8 | 1 | 6292 |
protein amino acid palmitoylation | 2.5415E-3 | 2 | 8 | 1 | 6292 |
protein modification process | 6.278E-3 | 2 | 499 | 2 | 6292 |
macromolecule modification | 8.1649E-3 | 2 | 569 | 2 | 6292 |
GPI anchor biosynthetic process | 8.8811E-3 | 2 | 28 | 1 | 6292 |
phosphoinositide biosynthetic process | 9.1975E-3 | 2 | 29 | 1 | 6292 |
GPI anchor metabolic process | 9.1975E-3 | 2 | 29 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
GTPase inhibitor activity | 9.5344E-4 | 2 | 3 | 1 | 6292 |
protein-cysteine S-palmitoleyltransferase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
protein-cysteine S-acyltransferase activity | 2.5415E-3 | 2 | 8 | 1 | 6292 |
palmitoyltransferase activity | 3.4937E-3 | 2 | 11 | 1 | 6292 |
S-acyltransferase activity | 4.1283E-3 | 2 | 13 | 1 | 6292 |
enzyme inhibitor activity | 8.5646E-3 | 2 | 27 | 1 | 6292 |