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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.885481651622]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
ENT3
  • clathrin vesicle coat
  • actin cortical patch
    		•
  • protein targeting
  • actin filament organization
  • endocytosis
  • actin cortical patch assembly
  • Golgi to endosome transport
    		•
  • protein binding
    		•
    ENT5
  • endosome
  • cytoplasm
  • clathrin vesicle coat
    		•
  • protein targeting
  • Golgi to endosome transport
    		•
  • clathrin binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    clathrin vesicle coat 4.5979E-6 2 14 2 6292
    clathrin coat 4.5979E-6 2 14 2 6292
    clathrin coated vesicle membrane 5.3053E-6 2 15 2 6292
    clathrin-coated vesicle 2.3495E-5 2 31 2 6292
    vesicle coat 2.8346E-5 2 34 2 6292
    coated vesicle membrane 3.0063E-5 2 35 2 6292
    cytoplasmic vesicle membrane 3.0063E-5 2 35 2 6292
    vesicle membrane 3.0063E-5 2 35 2 6292
    membrane coat 3.552E-5 2 38 2 6292
    coated membrane 3.552E-5 2 38 2 6292
    cytoplasmic vesicle part 3.744E-5 2 39 2 6292
    coated vesicle 1.7194E-4 2 83 2 6292
    cytoplasmic vesicle 2.8654E-4 2 107 2 6292
    membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    cytoplasmic membrane-bounded vesicle 2.8654E-4 2 107 2 6292
    vesicle 3.0291E-4 2 110 2 6292
    endomembrane system 3.9918E-3 2 398 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Golgi to endosome transport 2.779E-6 2 11 2 6292
    endosome transport 6.6999E-5 2 52 2 6292
    post-Golgi vesicle-mediated transport 1.151E-4 2 68 2 6292
    Golgi vesicle transport 7.0879E-4 2 168 2 6292
    protein targeting 1.3892E-3 2 235 2 6292
    intracellular protein transport 1.6363E-3 2 255 2 6292
    protein transport 1.8213E-3 2 269 2 6292
    establishment of protein localization 1.8485E-3 2 271 2 6292
    cellular protein localization 1.8898E-3 2 274 2 6292
    cellular macromolecule localization 2.0305E-3 2 284 2 6292
    protein localization 2.3118E-3 2 303 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    actin cortical patch assembly 4.4455E-3 2 14 1 6292
    cortical actin cytoskeleton organization 4.7627E-3 2 15 1 6292
    cortical cytoskeleton organization 4.7627E-3 2 15 1 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    clathrin binding 3.4937E-3 2 11 1 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle