From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.986225895267] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
ATG18 |
|
|
|
ATG21 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
fungal-type vacuole membrane | 1.3647E-4 | 2 | 74 | 2 | 6292 |
vacuolar membrane | 3.1973E-4 | 2 | 113 | 2 | 6292 |
vacuolar part | 3.6682E-4 | 2 | 121 | 2 | 6292 |
fungal-type vacuole | 6.2668E-4 | 2 | 158 | 2 | 6292 |
lytic vacuole | 6.2668E-4 | 2 | 158 | 2 | 6292 |
storage vacuole | 6.2668E-4 | 2 | 158 | 2 | 6292 |
vacuole | 1.0983E-3 | 2 | 209 | 2 | 6292 |
cytosol | 2.0305E-3 | 2 | 284 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
CVT pathway | 1.5158E-7 | 2 | 3 | 2 | 6292 |
vacuolar protein processing | 5.0527E-7 | 2 | 5 | 2 | 6292 |
protein processing | 2.5061E-5 | 2 | 32 | 2 | 6292 |
protein maturation | 3.9411E-5 | 2 | 40 | 2 | 6292 |
autophagy | 4.3504E-5 | 2 | 42 | 2 | 6292 |
protein targeting to vacuole | 1.1854E-4 | 2 | 69 | 2 | 6292 |
vacuolar transport | 3.312E-4 | 2 | 115 | 2 | 6292 |
protein targeting | 1.3892E-3 | 2 | 235 | 2 | 6292 |
intracellular protein transport | 1.6363E-3 | 2 | 255 | 2 | 6292 |
protein transport | 1.8213E-3 | 2 | 269 | 2 | 6292 |
establishment of protein localization | 1.8485E-3 | 2 | 271 | 2 | 6292 |
cellular protein localization | 1.8898E-3 | 2 | 274 | 2 | 6292 |
cellular macromolecule localization | 2.0305E-3 | 2 | 284 | 2 | 6292 |
protein localization | 2.3118E-3 | 2 | 303 | 2 | 6292 |
macromolecule localization | 3.9717E-3 | 2 | 397 | 2 | 6292 |
cellular catabolic process | 4.3405E-3 | 2 | 415 | 2 | 6292 |
catabolic process | 6.2027E-3 | 2 | 496 | 2 | 6292 |
intracellular transport | 7.7118E-3 | 2 | 553 | 2 | 6292 |
establishment of localization in cell | 9.0494E-3 | 2 | 599 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
phosphoinositide binding | 3.3651E-5 | 2 | 37 | 2 | 6292 |
phospholipid binding | 4.5626E-5 | 2 | 43 | 2 | 6292 |
lipid binding | 6.1895E-5 | 2 | 50 | 2 | 6292 |