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The directed movement of substances into, out of or within a vacuole. The process of directing proteins towards the vacuole, usually using signals contained within the protein. The process of targeting specific proteins to particular membrane-bounded subcellular organelles. Usually requires an organelle specific protein sequence motif. A vesicle organization process that takes place as part of the CVT pathway, and results in the formation of a double membrane-bounded cytosolic structure that sequesters precursor aminopeptidase I (prAPI). A constitutive biosynthetic process that occurs under nutrient-rich conditions, in which two resident vacuolar hydrolases, aminopeptidase I and alpha-mannosidase, are sequestered into vesicles; these vesicles are transported to, and then fuse with, the vacuole. This pathway is mostly observed in yeast.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: CVT pathway
Acc: GO:0032258
Aspect: Biological Process
Desc: A constitutive biosynthetic process that occurs under nutrient-rich conditions, in which two resident vacuolar hydrolases, aminopeptidase I and alpha-mannosidase, are sequestered into vesicles; these vesicles are transported to, and then fuse with, the vacuole. This pathway is mostly observed in yeast.
Synonyms:
  • cytoplasm-to-vacuole targeting
  • cytoplasm to vacuole targeting
Proteins in PDR annotated with:
   This term: 25 [Search]
   Term or descendants: 26 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0032258 - CVT pathway (interactive image map)
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