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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.00657114043]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RAP1
  • nucleus
  • nuclear telomeric heterochromatin
  • nuclear telomere cap complex
    		•
  • protection from non-homologous end joining at telomere
  • transcription from RNA polymerase II promoter
  • telomere maintenance via telomerase
  • chromatin silencing
  • chromatin silencing at telomere
    		•
  • DNA binding
  • transcription factor activity
    		•
    STN1
  • nuclear telomere cap complex
    		•
  • telomere capping
    		•
  • protein binding
  • telomeric DNA binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    telomere cap complex 2.779E-6 2 11 2 6292
    nuclear telomere cap complex 2.779E-6 2 11 2 6292
    nuclear chromosome, telomeric region 1.2783E-5 2 23 2 6292
    chromosome, telomeric region 1.7735E-5 2 27 2 6292
    protein-DNA complex 8.0641E-5 2 57 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292
    nuclear telomeric heterochromatin 2.224E-3 2 7 1 6292
    telomeric heterochromatin 2.224E-3 2 7 1 6292
    nuclear heterochromatin 2.224E-3 2 7 1 6292
    heterochromatin 2.224E-3 2 7 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    telomere capping 5.0527E-7 2 5 2 6292
    telomere maintenance in response to DNA damage 3.1786E-4 2 1 1 6292
    protection from non-homologous end joining at telomere 3.1786E-4 2 1 1 6292
    anatomical structure homeostasis 2.0592E-3 2 286 2 6292
    telomere organization 2.0592E-3 2 286 2 6292
    telomere maintenance 2.0592E-3 2 286 2 6292
    telomere maintenance via telomere lengthening 4.1283E-3 2 13 1 6292
    telomere maintenance via telomerase 4.1283E-3 2 13 1 6292
    RNA-dependent DNA replication 4.1283E-3 2 13 1 6292
    homeostatic process 4.1951E-3 2 408 2 6292
    regulation of biological quality 7.6561E-3 2 551 2 6292
    chromosome organization 7.7677E-3 2 555 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA binding 1.6492E-3 2 256 2 6292
    telomeric DNA binding 3.811E-3 2 12 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle