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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.20314415201]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
CDC50
  • trans-Golgi network
  • late endosome
  • integral to membrane of membrane fraction
    		•
  • phospholipid translocation
  • G1 phase of mitotic cell cycle
  • endocytosis
  • actin cortical patch localization
    		•
  • phospholipid-translocating ATPase activity
    		•
    DRS2
  • trans-Golgi network
    		•
  • phospholipid translocation
  • post-Golgi vesicle-mediated transport
  • intracellular protein transport
  • endocytosis
    		•
  • ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism
  • phospholipid-translocating ATPase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    trans-Golgi network 3.9411E-6 2 13 2 6292
    Golgi apparatus part 3.5475E-4 2 119 2 6292
    Golgi apparatus 7.3441E-4 2 171 2 6292
    integral to membrane of membrane fraction 9.5344E-4 2 3 1 6292
    late endosome 6.9813E-3 2 22 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    phospholipid translocation 1.0611E-6 2 7 2 6292
    lipid translocation 1.0611E-6 2 7 2 6292
    phospholipid transport 3.3348E-6 2 12 2 6292
    lipid transport 3.3651E-5 2 37 2 6292
    lipid localization 3.744E-5 2 39 2 6292
    endocytosis 1.9342E-4 2 88 2 6292
    membrane invagination 2.2085E-4 2 94 2 6292
    actin cortical patch localization 3.1786E-4 2 1 1 6292
    membrane organization 9.8542E-4 2 198 2 6292
    cellular membrane organization 9.8542E-4 2 198 2 6292
    vesicle-mediated transport 2.9119E-3 2 340 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    G1 phase of mitotic cell cycle 8.5646E-3 2 27 1 6292
    G1 phase 8.5646E-3 2 27 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    phospholipid-translocating ATPase activity 1.819E-6 2 9 2 6292
    phospholipid transporter activity 4.5979E-6 2 14 2 6292
    lipid transporter activity 8.6401E-6 2 19 2 6292
    ATPase activity, coupled to movement of substances 8.6451E-5 2 59 2 6292
    ATPase activity, coupled 5.5711E-4 2 149 2 6292
    ATPase activity 1.1194E-3 2 211 2 6292
    nucleoside-triphosphatase activity 2.7262E-3 2 329 2 6292
    substrate-specific transporter activity 2.8436E-3 2 336 2 6292
    hydrolase activity, acting on acid anhydrides 3.1391E-3 2 353 2 6292
    hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 3.1391E-3 2 353 2 6292
    pyrophosphatase activity 3.1391E-3 2 353 2 6292
    transporter activity 4.1132E-3 2 404 2 6292
    ATPase activity, coupled to transmembrane movement of ions, phosphorylative mechanism 4.4455E-3 2 14 1 6292
    ATPase activity, coupled to transmembrane movement of ions 9.1975E-3 2 29 1 6292
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