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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.41660147932]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
BIK1
  • spindle microtubule
  • cell cortex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • kinetochore
    		•
  • mitotic spindle elongation
  • mitotic anaphase B
  • mitotic spindle organization in nucleus
  • karyogamy involved in conjugation with cellular fusion
    		•
  • microtubule binding
    		•
    STU2
  • spindle microtubule
  • cell cortex
  • spindle pole body
  • condensed nuclear chromosome kinetochore
  • kinetochore
    		•
  • microtubule nucleation
  • mitotic spindle organization in nucleus
    		•
  • structural constituent of cytoskeleton
  • microtubule binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    spindle microtubule 6.8716E-6 2 17 2 6292
    microtubule 2.3495E-5 2 31 2 6292
    condensed nuclear chromosome kinetochore 5.9419E-5 2 49 2 6292
    condensed chromosome kinetochore 5.9419E-5 2 49 2 6292
    condensed chromosome, centromeric region 7.5032E-5 2 55 2 6292
    condensed nuclear chromosome, centromeric region 7.5032E-5 2 55 2 6292
    kinetochore 8.9432E-5 2 60 2 6292
    microtubule organizing center 9.8679E-5 2 63 2 6292
    spindle pole body 9.8679E-5 2 63 2 6292
    chromosome, centromeric region 1.1171E-4 2 67 2 6292
    spindle pole 1.151E-4 2 68 2 6292
    condensed nuclear chromosome 1.8468E-4 2 86 2 6292
    spindle 1.9786E-4 2 89 2 6292
    condensed chromosome 2.2085E-4 2 94 2 6292
    microtubule cytoskeleton 2.8118E-4 2 106 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    nuclear chromosome part 9.0721E-4 2 190 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292
    nuclear chromosome 1.3075E-3 2 228 2 6292
    chromosomal part 1.413E-3 2 237 2 6292
    chromosome 1.8898E-3 2 274 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    mitotic spindle organization in nucleus 1.6421E-5 2 26 2 6292
    mitotic spindle organization 5.6994E-5 2 48 2 6292
    spindle organization 5.9419E-5 2 49 2 6292
    microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
    microtubule-based process 3.0847E-4 2 111 2 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    mitotic anaphase B 1.9064E-3 2 6 1 6292
    M phase 2.1762E-3 2 294 2 6292
    anaphase 2.224E-3 2 7 1 6292
    mitotic anaphase 2.224E-3 2 7 1 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    karyogamy involved in conjugation with cellular fusion 5.7138E-3 2 18 1 6292
    karyogamy 5.7138E-3 2 18 1 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    mitotic spindle elongation 6.6645E-3 2 21 1 6292
    spindle elongation 6.6645E-3 2 21 1 6292
    cell cycle 6.95E-3 2 525 2 6292
    microtubule nucleation 7.2981E-3 2 23 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    microtubule binding 2.2737E-6 2 10 2 6292
    tubulin binding 9.6001E-6 2 20 2 6292
    cytoskeletal protein binding 8.6451E-5 2 59 2 6292
    protein binding 9.4468E-3 2 612 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle