From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classfier did not use Gene Ontology annotations. [FDR: 0.021] [SVM Score: 0.913412582627] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
POP1 |
|
|
|
POP8 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
nucleolar ribonuclease P complex | 1.819E-6 | 2 | 9 | 2 | 6292 |
multimeric ribonuclease P complex | 1.819E-6 | 2 | 9 | 2 | 6292 |
ribonuclease MRP complex | 2.2737E-6 | 2 | 10 | 2 | 6292 |
ribonuclease P complex | 2.2737E-6 | 2 | 10 | 2 | 6292 |
nucleolar part | 5.0022E-5 | 2 | 45 | 2 | 6292 |
small nucleolar ribonucleoprotein complex | 1.2915E-4 | 2 | 72 | 2 | 6292 |
nucleolus | 1.1194E-3 | 2 | 211 | 2 | 6292 |
nuclear lumen | 5.1728E-3 | 2 | 453 | 2 | 6292 |
ribonucleoprotein complex | 6.6615E-3 | 2 | 514 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mRNA cleavage | 1.5158E-5 | 2 | 25 | 2 | 6292 |
nucleic acid phosphodiester bond hydrolysis | 5.2295E-5 | 2 | 46 | 2 | 6292 |
tRNA processing | 1.7194E-4 | 2 | 83 | 2 | 6292 |
tRNA metabolic process | 3.6076E-4 | 2 | 120 | 2 | 6292 |
rRNA processing | 4.1068E-4 | 2 | 128 | 2 | 6292 |
rRNA metabolic process | 4.7071E-4 | 2 | 137 | 2 | 6292 |
mRNA processing | 6.1087E-4 | 2 | 156 | 2 | 6292 |
mRNA metabolic process | 1.1408E-3 | 2 | 213 | 2 | 6292 |
ncRNA processing | 1.1624E-3 | 2 | 215 | 2 | 6292 |
ncRNA metabolic process | 1.6621E-3 | 2 | 257 | 2 | 6292 |
ribosome biogenesis | 3.0157E-3 | 2 | 346 | 2 | 6292 |
ribonucleoprotein complex biogenesis | 3.5243E-3 | 2 | 374 | 2 | 6292 |
RNA processing | 3.6384E-3 | 2 | 380 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
ribonuclease P activity | 2.2737E-6 | 2 | 10 | 2 | 6292 |
ribonuclease MRP activity | 2.2737E-6 | 2 | 10 | 2 | 6292 |
tRNA-specific ribonuclease activity | 5.3053E-6 | 2 | 15 | 2 | 6292 |
endoribonuclease activity, producing 5'-phosphomonoesters | 7.7306E-6 | 2 | 18 | 2 | 6292 |
endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 1.2783E-5 | 2 | 23 | 2 | 6292 |
endoribonuclease activity | 1.7735E-5 | 2 | 27 | 2 | 6292 |
endonuclease activity | 9.2464E-5 | 2 | 61 | 2 | 6292 |
ribonuclease activity | 5.5711E-4 | 2 | 149 | 2 | 6292 |
nuclease activity | 9.9543E-4 | 2 | 199 | 2 | 6292 |
hydrolase activity, acting on ester bonds | 2.929E-3 | 2 | 341 | 2 | 6292 |