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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
NSP1
  • nuclear pore
    		•
  • protein export from nucleus
  • ribosomal protein import into nucleus
  • mRNA export from nucleus
  • ribosomal large subunit export from nucleus
  • rRNA export from nucleus
  • RNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • protein import into nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
    		•
  • structural molecule activity
    		•
    NUP133
  • nuclear pore
    		•
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • chromosome localization
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • DNA metabolic process
  • protein export from nucleus
  • ribosomal protein import into nucleus
    		•
  • structural molecule activity
    		•
    NUP159
  • nuclear pore
    		•
  • mRNA export from nucleus
  • rRNA export from nucleus
  • ribosomal subunit export from nucleus
  • nuclear pore organization
    		•
  • structural molecule activity
    		•
    NUP82
  • nuclear pore
    		•
  • mRNA export from nucleus
  • rRNA export from nucleus
  • nuclear pore organization
  • snRNP protein import into nucleus
  • mRNA-binding (hnRNP) protein import into nucleus
  • snRNA export from nucleus
  • tRNA export from nucleus
  • NLS-bearing substrate import into nucleus
  • protein export from nucleus
  • ribosomal protein import into nucleus
    		•
  • structural molecule activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    pore complex 4.1495E-9 4 52 4 6292
    nuclear pore 4.1495E-9 4 52 4 6292
    nuclear envelope 9.7163E-7 4 199 4 6292
    integral to membrane 2.6373E-6 4 255 4 6292
    intrinsic to membrane 2.9409E-6 4 262 4 6292
    endomembrane system 1.5784E-5 4 398 4 6292
    envelope 4.1044E-5 4 505 4 6292
    organelle envelope 4.1044E-5 4 505 4 6292
    membrane part 1.2155E-4 4 662 4 6292
    nuclear part 9.4015E-4 4 1103 4 6292
    protein complex 1.0617E-3 4 1137 4 6292
    membrane 1.3089E-3 4 1198 4 6292
    macromolecular complex 4.5471E-3 4 1635 4 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    rRNA export from nucleus 2.69E-10 4 27 4 6292
    rRNA transport 2.69E-10 4 27 4 6292
    nuclear pore organization 3.1383E-10 4 28 4 6292
    nucleus organization 5.6296E-9 4 56 4 6292
    mRNA export from nucleus 1.2482E-8 4 68 4 6292
    mRNA transport 1.2482E-8 4 68 4 6292
    RNA export from nucleus 2.4242E-8 4 80 4 6292
    RNA transport 2.5501E-8 4 81 4 6292
    nucleic acid transport 2.5501E-8 4 81 4 6292
    establishment of RNA localization 2.5501E-8 4 81 4 6292
    RNA localization 4.2827E-8 4 92 4 6292
    nucleobase, nucleoside, nucleotide and nucleic acid transport 5.0917E-8 4 96 4 6292
    nuclear export 6.7767E-8 4 103 4 6292
    ribosomal protein import into nucleus 1.7031E-7 4 23 3 6292
    snRNP protein import into nucleus 1.7031E-7 4 23 3 6292
    snRNA export from nucleus 1.7031E-7 4 23 3 6292
    NLS-bearing substrate import into nucleus 1.7031E-7 4 23 3 6292
    snRNA transport 1.7031E-7 4 23 3 6292
    nuclear transport 1.741E-7 4 130 4 6292
    nucleocytoplasmic transport 1.741E-7 4 130 4 6292
    mRNA-binding (hnRNP) protein import into nucleus 2.2113E-7 4 25 3 6292
    tRNA export from nucleus 3.1485E-7 4 28 3 6292
    tRNA transport 3.1485E-7 4 28 3 6292
    protein export from nucleus 4.7646E-7 4 32 3 6292
    nuclear import 1.6583E-6 4 48 3 6292
    protein localization in nucleus 1.6583E-6 4 48 3 6292
    protein import into nucleus 1.6583E-6 4 48 3 6292
    cellular macromolecular complex subunit organization 2.8077E-6 4 259 4 6292
    ribosome biogenesis 8.9951E-6 4 346 4 6292
    organelle localization 9.4278E-6 4 85 3 6292
    macromolecular complex subunit organization 1.02E-5 4 357 4 6292
    ribonucleoprotein complex biogenesis 1.2296E-5 4 374 4 6292
    macromolecule localization 1.5626E-5 4 397 4 6292
    protein import 1.9433E-5 4 108 3 6292
    protein localization in organelle 5.1173E-5 4 149 3 6292
    intracellular transport 5.908E-5 4 553 4 6292
    establishment of localization in cell 8.1397E-5 4 599 4 6292
    establishment of ribosome localization 9.8027E-5 4 26 2 6292
    ribosome localization 9.8027E-5 4 26 2 6292
    ribosomal subunit export from nucleus 9.8027E-5 4 26 2 6292
    cellular localization 1.0815E-4 4 643 4 6292
    cellular component biogenesis 1.4687E-4 4 694 4 6292
    protein targeting 2.0015E-4 4 235 3 6292
    intracellular protein transport 2.5535E-4 4 255 3 6292
    protein transport 2.9943E-4 4 269 3 6292
    establishment of protein localization 3.0611E-4 4 271 3 6292
    cellular protein localization 3.1631E-4 4 274 3 6292
    cellular macromolecule localization 3.5193E-4 4 284 3 6292
    protein localization 4.2667E-4 4 303 3 6292
    establishment of organelle localization 4.4515E-4 4 55 2 6292
    transport 6.2722E-4 4 997 4 6292
    establishment of localization 6.5541E-4 4 1008 4 6292
    localization 8.0172E-4 4 1060 4 6292
    organelle organization 1.0248E-3 4 1127 4 6292
    chromosome localization 2.5411E-3 4 4 1 6292
    cellular component organization 3.9851E-3 4 1582 4 6292
    ribosomal large subunit export from nucleus 5.7106E-3 4 9 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    structural molecule activity 8.286E-6 4 339 4 6292
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