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View Protein Complex Details

Complex Overview

From Publication: Mewes, H. W. et al. MIPS: Analysis and annotation of proteins from whole genomes. Nucleic Acids Res. 32, D41-D44
Notes: MIPS hand-curated complex set. MIPS complex ID: 270.20.30
Complex Size: 9 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ASK1
  • condensed nuclear chromosome, centromeric region
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DAD1
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DAD2
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DAD3
  • DASH complex
  • spindle
  • kinetochore
  • mitotic spindle organization in nucleus
  • mitosis
  • regulation of microtubule polymerization or depolymerization
  • protein binding
  • DAD4
  • DASH complex
  • spindle
  • kinetochore
  • mitotic spindle organization in nucleus
  • mitosis
  • regulation of microtubule polymerization or depolymerization
  • protein binding
  • DAM1
  • spindle midzone
  • kinetochore microtubule
  • DASH complex
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • DUO1
  • spindle microtubule
  • DASH complex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • SPC19
  • spindle microtubule
  • DASH complex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • microtubule nucleation
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • SPC34
  • spindle microtubule
  • DASH complex
  • spindle pole body
  • spindle
  • condensed nuclear chromosome kinetochore
  • microtubule nucleation
  • mitotic spindle organization in nucleus
  • regulation of microtubule polymerization or depolymerization
  • structural constituent of cytoskeleton
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    DASH complex 5.1949E-27 9 12 9 6292
    condensed nuclear chromosome kinetochore 4.8512E-20 9 49 9 6292
    condensed chromosome kinetochore 4.8512E-20 9 49 9 6292
    condensed chromosome, centromeric region 1.5014E-19 9 55 9 6292
    condensed nuclear chromosome, centromeric region 1.5014E-19 9 55 9 6292
    kinetochore 3.4907E-19 9 60 9 6292
    chromosome, centromeric region 1.0096E-18 9 67 9 6292
    condensed nuclear chromosome 1.0859E-17 9 86 9 6292
    spindle 1.5009E-17 9 89 9 6292
    condensed chromosome 2.5117E-17 9 94 9 6292
    microtubule cytoskeleton 7.7542E-17 9 106 9 6292
    nuclear chromosome part 1.7323E-14 9 190 9 6292
    cytoskeletal part 2.9057E-14 9 201 9 6292
    cytoskeleton 5.625E-14 9 216 9 6292
    nuclear chromosome 9.2334E-14 9 228 9 6292
    chromosomal part 1.3163E-13 9 237 9 6292
    chromosome 4.96E-13 9 274 9 6292
    spindle microtubule 4.5585E-9 9 17 4 6292
    non-membrane-bounded organelle 4.2994E-8 9 959 9 6292
    intracellular non-membrane-bounded organelle 4.2994E-8 9 959 9 6292
    microtubule 5.9731E-8 9 31 4 6292
    nuclear part 1.5218E-7 9 1103 9 6292
    protein complex 2.0019E-7 9 1137 9 6292
    macromolecular complex 5.3146E-6 9 1635 9 6292
    nucleus 3.9292E-5 9 2041 9 6292
    microtubule organizing center 7.6999E-5 9 63 3 6292
    spindle pole body 7.6999E-5 9 63 3 6292
    spindle pole 9.6826E-5 9 68 3 6292
    organelle part 1.0749E-4 9 2282 9 6292
    intracellular organelle part 1.0749E-4 9 2282 9 6292
    membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    intracellular membrane-bounded organelle 9.9391E-3 9 3771 9 6292
    kinetochore microtubule 9.9746E-3 9 7 1 6292
    spindle midzone 9.9746E-3 9 7 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    regulation of microtubule cytoskeleton organization 5.7403E-25 9 17 9 6292
    regulation of microtubule polymerization or depolymerization 5.7403E-25 9 17 9 6292
    regulation of microtubule-based process 5.7403E-25 9 17 9 6292
    microtubule polymerization or depolymerization 1.1481E-24 9 18 9 6292
    regulation of cytoskeleton organization 3.966E-24 9 20 9 6292
    mitotic spindle organization in nucleus 7.378E-23 9 26 9 6292
    mitotic spindle organization 3.9601E-20 9 48 9 6292
    spindle organization 4.8512E-20 9 49 9 6292
    regulation of organelle organization 8.6874E-20 9 52 9 6292
    regulation of cellular component organization 2.9657E-18 9 75 9 6292
    microtubule cytoskeleton organization 3.3746E-17 9 97 9 6292
    microtubule-based process 1.1932E-16 9 111 9 6292
    cytoskeleton organization 1.0408E-13 9 231 9 6292
    mitotic cell cycle 2.5718E-13 9 255 9 6292
    M phase 9.4366E-13 9 294 9 6292
    cell cycle phase 8.8752E-12 9 376 9 6292
    cell cycle process 9.8414E-11 9 490 9 6292
    cell cycle 1.8403E-10 9 525 9 6292
    regulation of cellular process 7.978E-9 9 796 9 6292
    regulation of biological process 1.0907E-8 9 824 9 6292
    organelle organization 1.8484E-7 9 1127 9 6292
    biological regulation 3.591E-7 9 1213 9 6292
    cellular component organization 3.9477E-6 9 1582 9 6292
    microtubule nucleation 4.5308E-4 9 23 2 6292
    mitosis 9.0312E-3 9 104 2 6292
    nuclear division 9.3697E-3 9 106 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of cytoskeleton 7.0959E-14 9 53 7 6292
    structural molecule activity 4.0688E-8 9 339 7 6292

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    Created and Maintained by: Michael Riffle