






| From Publication: | Riffle <i>et al</i>. (2010) (Unpublished Data) | 
| Notes: | Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7 | 
| Complex Size: | 3 proteins | 
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term | 
				P-value | 
				A | 
				B | 
				I | 
				T | 				
			
| mitochondrial pyruvate dehydrogenase complex | 4.8197E-10 | 3 | 6 | 3 | 6292 | 
| pyruvate dehydrogenase complex | 4.8197E-10 | 3 | 6 | 3 | 6292 | 
| mitochondrial matrix | 2.1525E-5 | 3 | 176 | 3 | 6292 | 
| mitochondrial lumen | 2.1525E-5 | 3 | 176 | 3 | 6292 | 
| mitochondrial part | 4.2773E-4 | 3 | 475 | 3 | 6292 | 
| organelle lumen | 1.1495E-3 | 3 | 660 | 3 | 6292 | 
| intracellular organelle lumen | 1.1495E-3 | 3 | 660 | 3 | 6292 | 
| membrane-enclosed lumen | 1.3717E-3 | 3 | 700 | 3 | 6292 | 
| mitochondrion | 5.7035E-3 | 3 | 1125 | 3 | 6292 | 
| protein complex | 5.8881E-3 | 3 | 1137 | 3 | 6292 | 
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term | 
				P-value | 
				A | 
				B | 
				I | 
				T | 				
			
| pyruvate metabolic process | 3.1916E-7 | 3 | 44 | 3 | 6292 | 
| monocarboxylic acid metabolic process | 9.4487E-6 | 3 | 134 | 3 | 6292 | 
| organic acid metabolic process | 1.4698E-4 | 3 | 333 | 3 | 6292 | 
| oxoacid metabolic process | 1.4698E-4 | 3 | 333 | 3 | 6292 | 
| carboxylic acid metabolic process | 1.4698E-4 | 3 | 333 | 3 | 6292 | 
| cellular ketone metabolic process | 1.6493E-4 | 3 | 346 | 3 | 6292 | 
| acetyl-CoA biosynthetic process from pyruvate | 9.5344E-4 | 3 | 2 | 1 | 6292 | 
| small molecule metabolic process | 1.7562E-3 | 3 | 760 | 3 | 6292 | 
| acetyl-CoA biosynthetic process | 1.9063E-3 | 3 | 4 | 1 | 6292 | 
| acetyl-CoA metabolic process | 9.5071E-3 | 3 | 20 | 1 | 6292 | 
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
| GO Term | 
				P-value | 
				A | 
				B | 
				I | 
				T | 				
			
| dihydrolipoyllysine-residue acetyltransferase activity | 4.768E-4 | 3 | 1 | 1 | 6292 | 
| dihydrolipoamide S-acyltransferase activity | 4.768E-4 | 3 | 1 | 1 | 6292 | 
| S-acetyltransferase activity | 9.5344E-4 | 3 | 2 | 1 | 6292 | 
| pyruvate dehydrogenase (acetyl-transferring) activity | 1.9063E-3 | 3 | 4 | 1 | 6292 | 
| pyruvate dehydrogenase activity | 1.9063E-3 | 3 | 4 | 1 | 6292 | 
| oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor | 2.3825E-3 | 3 | 5 | 1 | 6292 | 
| S-acyltransferase activity | 6.1865E-3 | 3 | 13 | 1 | 6292 |