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Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MMS4
  • nucleus
  • Holliday junction resolvase complex
    		•
  • DNA repair
  • reciprocal meiotic recombination
  • DNA topological change
  • response to DNA damage stimulus
    		•
  • transcription coactivator activity
  • endonuclease activity
  • crossover junction endodeoxyribonuclease activity
    		•
    MUS81
  • nucleus
  • Holliday junction resolvase complex
    		•
  • DNA repair
  • reciprocal meiotic recombination
  • DNA topological change
  • response to DNA damage stimulus
    		•
  • endonuclease activity
  • crossover junction endodeoxyribonuclease activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    Holliday junction resolvase complex 1.5158E-7 2 3 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    DNA topological change 1.4147E-6 2 8 2 6292
    reciprocal meiotic recombination 4.1432E-5 2 41 2 6292
    DNA conformation change 8.3521E-5 2 58 2 6292
    meiosis I 1.5567E-4 2 79 2 6292
    DNA recombination 3.2544E-4 2 114 2 6292
    M phase of meiotic cell cycle 6.427E-4 2 160 2 6292
    meiosis 6.427E-4 2 160 2 6292
    meiotic cell cycle 6.7534E-4 2 164 2 6292
    DNA repair 9.2646E-4 2 192 2 6292
    response to DNA damage stimulus 1.4011E-3 2 236 2 6292
    cellular response to stress 2.1173E-3 2 290 2 6292
    M phase 2.1762E-3 2 294 2 6292
    cell cycle phase 3.5621E-3 2 376 2 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    cell cycle 6.95E-3 2 525 2 6292
    DNA metabolic process 8.631E-3 2 585 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    crossover junction endodeoxyribonuclease activity 1.5158E-7 2 3 2 6292
    endodeoxyribonuclease activity, producing 3'-phosphomonoesters 3.0316E-7 2 4 2 6292
    endonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 3'-phosphomonoesters 1.819E-6 2 9 2 6292
    endodeoxyribonuclease activity 1.1672E-5 2 22 2 6292
    deoxyribonuclease activity 2.0514E-5 2 29 2 6292
    endonuclease activity 9.2464E-5 2 61 2 6292
    nuclease activity 9.9543E-4 2 199 2 6292
    hydrolase activity, acting on ester bonds 2.929E-3 2 341 2 6292
    transcription coactivator activity 6.6645E-3 2 21 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle