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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 11 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
RET1
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPA190
  • DNA-directed RNA polymerase I complex
    		•
  • transcription from RNA polymerase I promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB10
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB5
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPB8
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC19
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC40
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC53
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPC82
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
  • ribosome biogenesis
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO26
  • DNA-directed RNA polymerase I complex
  • DNA-directed RNA polymerase III complex
  • DNA-directed RNA polymerase II, core complex
    		•
  • transcription from RNA polymerase III promoter
  • transcription from RNA polymerase I promoter
  • transcription from RNA polymerase II promoter
    		•
  • DNA-directed RNA polymerase activity
    		•
    RPO31
  • DNA-directed RNA polymerase III complex
    		•
  • transcription from RNA polymerase III promoter
    		•
  • DNA-directed RNA polymerase activity
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase complex 5.5721E-27 11 31 11 6292
    nuclear DNA-directed RNA polymerase complex 5.5721E-27 11 31 11 6292
    DNA-directed RNA polymerase complex 5.5721E-27 11 31 11 6292
    DNA-directed RNA polymerase III complex 8.0318E-27 11 17 10 6292
    DNA-directed RNA polymerase I complex 1.4613E-17 11 14 7 6292
    nucleoplasm part 7.1191E-14 11 245 10 6292
    nucleoplasm 1.5186E-13 11 264 10 6292
    nucleolar part 1.899E-13 11 45 7 6292
    nuclear lumen 2.4047E-13 11 453 11 6292
    organelle lumen 1.5694E-11 11 660 11 6292
    intracellular organelle lumen 1.5694E-11 11 660 11 6292
    membrane-enclosed lumen 3.0124E-11 11 700 11 6292
    DNA-directed RNA polymerase II, core complex 2.486E-9 11 12 4 6292
    nuclear part 4.6103E-9 11 1103 11 6292
    protein complex 6.4478E-9 11 1137 11 6292
    nucleolus 1.2727E-8 11 211 7 6292
    macromolecular complex 3.5578E-7 11 1635 11 6292
    DNA-directed RNA polymerase II, holoenzyme 1.7735E-6 11 56 4 6292
    nucleus 4.1084E-6 11 2041 11 6292
    organelle part 1.4064E-5 11 2282 11 6292
    intracellular organelle part 1.4064E-5 11 2282 11 6292
    non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    intracellular non-membrane-bounded organelle 3.5121E-4 11 959 7 6292
    membrane-bounded organelle 3.5629E-3 11 3771 11 6292
    intracellular membrane-bounded organelle 3.5629E-3 11 3771 11 6292
    intracellular organelle 8.2563E-3 11 4070 11 6292
    organelle 8.2787E-3 11 4071 11 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    transcription from RNA polymerase III promoter 1.9464E-22 11 38 10 6292
    transcription from RNA polymerase I promoter 8.5909E-15 11 30 7 6292
    transcription, DNA-dependent 7.701E-13 11 503 11 6292
    RNA biosynthetic process 8.5956E-13 11 508 11 6292
    transcription 2.1622E-12 11 552 11 6292
    RNA metabolic process 9.2688E-10 11 954 11 6292
    cellular macromolecule biosynthetic process 1.0373E-8 11 1187 11 6292
    macromolecule biosynthetic process 1.0568E-8 11 1189 11 6292
    gene expression 2.4488E-8 11 1283 11 6292
    nucleic acid metabolic process 7.2197E-8 11 1415 11 6292
    nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 2.2108E-7 11 1566 11 6292
    cellular biosynthetic process 2.2264E-7 11 1567 11 6292
    biosynthetic process 2.841E-7 11 1602 11 6292
    cellular nitrogen compound metabolic process 8.537E-7 11 1770 11 6292
    nitrogen compound metabolic process 9.7232E-7 11 1791 11 6292
    cellular macromolecule metabolic process 1.4269E-5 11 2285 11 6292
    macromolecule metabolic process 1.9349E-5 11 2349 11 6292
    primary metabolic process 1.9438E-4 11 2896 11 6292
    cellular metabolic process 3.2347E-4 11 3033 11 6292
    metabolic process 5.03E-4 11 3157 11 6292
    transcription from RNA polymerase II promoter 1.9322E-3 11 335 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    RNA polymerase activity 1.8828E-26 11 34 11 6292
    DNA-directed RNA polymerase activity 1.8828E-26 11 34 11 6292
    nucleotidyltransferase activity 3.5505E-18 11 168 11 6292
    transferase activity, transferring phosphorus-containing groups 1.0364E-13 11 420 11 6292
    transferase activity 1.2678E-10 11 797 11 6292
    catalytic activity 7.2915E-6 11 2150 11 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle