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View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
RPL10
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL11B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL15A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL17A
  • cytoplasm
  • translation
  • structural constituent of ribosome
  • RPL18A, RPL18B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • translation
  • structural constituent of ribosome
  • RPL1A, RPL1B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • RNA processing
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPL20A
  • translation
  • structural constituent of ribosome
  • RPL2A, RPL2B
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • regulation of translation
  • response to drug
  • translation
  • RNA binding
  • structural constituent of ribosome
  • rRNA binding
  • RPL3
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • structural constituent of ribosome
  • RPL42B, RPL42A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • response to antibiotic
  • response to cycloheximide
  • translation
  • structural constituent of ribosome
  • RPL4A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPL6A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic large ribosomal subunit
  • ribosome
  • intracellular
  • ribosomal large subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS14A
  • small nucleolar ribonucleoprotein complex
  • maturation of SSU-rRNA
  • telomere maintenance
  • ribosomal small subunit assembly
  • translation
  • RNA binding
  • structural constituent of ribosome
  • RPS1A
  • ribonucleoprotein complex
  • cytoplasm
  • cytosolic small ribosomal subunit
  • ribosome
  • 90S preribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS5
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • small ribosomal subunit
  • 90S preribosome
  • ribosome
  • intracellular
  • translation
  • structural constituent of ribosome
  • RPS8B, RPS8A
  • ribonucleoprotein complex
  • cytosolic small ribosomal subunit
  • cytoplasm
  • 90S preribosome
  • ribosome
  • intracellular
  • regulation of translation
  • maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
  • translation
  • structural constituent of ribosome
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytosolic ribosome 1.1436E-21 16 101 13 6292
    cytosolic part 1.5246E-20 16 122 13 6292
    ribosomal subunit 3.6186E-18 16 183 13 6292
    cytosolic large ribosomal subunit 2.1723E-17 16 60 10 6292
    cytosol 1.2249E-15 16 284 13 6292
    ribosome 1.6124E-15 16 290 13 6292
    large ribosomal subunit 1.2932E-14 16 110 10 6292
    ribonucleoprotein complex 5.1434E-14 16 514 14 6292
    non-membrane-bounded organelle 7.9667E-9 16 959 13 6292
    intracellular non-membrane-bounded organelle 7.9667E-9 16 959 13 6292
    macromolecular complex 4.2472E-7 16 1635 14 6292
    90S preribosome 8.9795E-6 16 17 3 6292
    preribosome 7.6962E-5 16 34 3 6292
    cytosolic small ribosomal subunit 1.0783E-4 16 38 3 6292
    organelle part 3.0309E-4 16 2282 13 6292
    intracellular organelle part 3.0309E-4 16 2282 13 6292
    small ribosomal subunit 7.529E-4 16 73 3 6292
    cytoplasmic part 7.9119E-4 16 2482 13 6292
    cytoplasm 8.9496E-3 16 3552 14 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation 1.9504E-20 16 376 16 6292
    cellular protein metabolic process 4.7313E-13 16 1074 16 6292
    protein metabolic process 1.1685E-12 16 1136 16 6292
    cellular macromolecule biosynthetic process 2.3702E-12 16 1187 16 6292
    macromolecule biosynthetic process 2.4353E-12 16 1189 16 6292
    gene expression 8.2892E-12 16 1283 16 6292
    cellular biosynthetic process 2.0673E-10 16 1567 16 6292
    biosynthetic process 2.9487E-10 16 1602 16 6292
    cellular macromolecule metabolic process 8.851E-8 16 2285 16 6292
    macromolecule metabolic process 1.379E-7 16 2349 16 6292
    ribosomal subunit assembly 1.7214E-7 16 55 5 6292
    ribosome assembly 3.7233E-7 16 64 5 6292
    organelle assembly 5.4481E-7 16 69 5 6292
    ribonucleoprotein complex assembly 2.3047E-6 16 92 5 6292
    ribosomal large subunit assembly 2.6696E-6 16 41 4 6292
    primary metabolic process 3.9666E-6 16 2896 16 6292
    cellular metabolic process 8.3256E-6 16 3033 16 6292
    regulation of translation 1.0161E-5 16 57 4 6292
    posttranscriptional regulation of gene expression 1.3341E-5 16 61 4 6292
    metabolic process 1.5832E-5 16 3157 16 6292
    ribosomal large subunit biogenesis 1.7203E-5 16 65 4 6292
    regulation of cellular protein metabolic process 2.0597E-5 16 68 4 6292
    regulation of protein metabolic process 2.8835E-5 16 74 4 6292
    cellular macromolecular complex assembly 6.46E-5 16 182 5 6292
    ribosome biogenesis 1.3245E-4 16 346 6 6292
    ribonucleoprotein complex biogenesis 2.037E-4 16 374 6 6292
    cellular macromolecular complex subunit organization 3.4181E-4 16 259 5 6292
    macromolecular complex assembly 4.9873E-4 16 281 5 6292
    macromolecular complex subunit organization 1.484E-3 16 357 5 6292
    cellular component assembly 2.0794E-3 16 385 5 6292
    response to cycloheximide 2.5429E-3 16 1 1 6292
    response to cycloalkane 2.5429E-3 16 1 1 6292
    response to organic cyclic substance 2.5429E-3 16 1 1 6292
    cellular process 3.565E-3 16 4426 16 6292
    cellular component biogenesis 5.3341E-3 16 694 6 6292
    response to antibiotic 7.6106E-3 16 3 1 6292
    maturation of SSU-rRNA 9.5338E-3 16 59 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    structural constituent of ribosome 1.574E-24 16 212 16 6292
    structural molecule activity 3.587E-21 16 339 16 6292
    RNA binding 1.6796E-3 16 367 5 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle