YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

View Protein Complex Details

Complex Overview

From Publication: Riffle <i>et al</i>. (2010) (Unpublished Data)
Notes: Complex predicted from the combined set of Gavin (2002), Gavin (2006), Ho (2002) and Krogan (2006); at p-value cutoff of 1E-7
Complex Size: 13 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
BRX1
  • nucleolus
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • 5S rRNA binding
  • rRNA primary transcript binding
  • CIC1
  • proteasome complex
  • nucleolus
  • protein catabolic process
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • protein binding, bridging
  • ERB1
  • nucleus
  • nucleolus
  • rRNA processing
  • molecular_function
  • HAS1
  • nuclear envelope
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • RNA-dependent ATPase activity
  • ATP-dependent RNA helicase activity
  • MAK21
  • Noc1p-Noc2p complex
  • ribosome biogenesis
  • ribosomal large subunit assembly
  • molecular_function
  • MAK5
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • ribosomal large subunit assembly
  • ATP-dependent RNA helicase activity
  • NOC2
  • nucleus
  • Noc2p-Noc3p complex
  • mitochondrion
  • Noc1p-Noc2p complex
  • ribosomal subunit export from nucleus
  • ribosome biogenesis
  • ribosome assembly
  • molecular_function
  • NOP12
  • nucleolus
  • rRNA metabolic process
  • RNA binding
  • NOP2
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA methyltransferase activity
  • S-adenosylmethionine-dependent methyltransferase activity
  • NOP4
  • nucleolus
  • ribosome biogenesis
  • rRNA processing
  • RNA binding
  • PUF6
  • nucleus
  • nucleolus
  • regulation of transcription, mating-type specific
  • ribosome biogenesis
  • mRNA binding
  • specific transcriptional repressor activity
  • RLP7
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • processing of 27S pre-rRNA
  • rRNA binding
  • YTM1
  • nucleus
  • nucleolus
  • ribosomal large subunit biogenesis
  • ribosome biogenesis
  • molecular_function
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    nucleolus 4.7097E-20 13 211 13 6292
    nuclear lumen 1.1883E-15 13 453 13 6292
    organelle lumen 1.6732E-13 13 660 13 6292
    intracellular organelle lumen 1.6732E-13 13 660 13 6292
    membrane-enclosed lumen 3.6201E-13 13 700 13 6292
    non-membrane-bounded organelle 2.2351E-11 13 959 13 6292
    intracellular non-membrane-bounded organelle 2.2351E-11 13 959 13 6292
    nuclear part 1.3925E-10 13 1103 13 6292
    nucleus 4.29E-7 13 2041 13 6292
    organelle part 1.8381E-6 13 2282 13 6292
    intracellular organelle part 1.8381E-6 13 2282 13 6292
    Noc1p-Noc2p complex 3.9411E-6 13 2 2 6292
    Noc complex 3.9273E-5 13 5 2 6292
    preribosome, large subunit precursor 1.4073E-4 13 9 2 6292
    90S preribosome 5.2669E-4 13 17 2 6292
    membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    intracellular membrane-bounded organelle 1.2767E-3 13 3771 13 6292
    preribosome 2.13E-3 13 34 2 6292
    intracellular organelle 3.4477E-3 13 4070 13 6292
    organelle 3.4587E-3 13 4071 13 6292
    nucleolar part 3.7109E-3 13 45 2 6292
    Noc2p-Noc3p complex 4.1283E-3 13 2 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    ribosome biogenesis 7.8761E-15 13 346 12 6292
    ribonucleoprotein complex biogenesis 2.0245E-14 13 374 12 6292
    cellular component biogenesis 3.4829E-11 13 694 12 6292
    ribosomal large subunit biogenesis 1.558E-9 13 65 6 6292
    rRNA metabolic process 1.4461E-7 13 137 6 6292
    rRNA processing 3.6391E-6 13 128 5 6292
    ncRNA metabolic process 5.9049E-6 13 257 6 6292
    ribosome assembly 6.4995E-6 13 64 4 6292
    organelle assembly 8.7925E-6 13 69 4 6292
    ribonucleoprotein complex assembly 2.7675E-5 13 92 4 6292
    ncRNA processing 4.5744E-5 13 215 5 6292
    ribosomal large subunit assembly 7.0211E-5 13 41 3 6292
    ribosomal subunit assembly 1.6993E-4 13 55 3 6292
    cellular macromolecular complex assembly 3.9465E-4 13 182 4 6292
    RNA processing 6.7223E-4 13 380 5 6292
    RNA metabolic process 1.3355E-3 13 954 7 6292
    cellular macromolecular complex subunit organization 1.4943E-3 13 259 4 6292
    macromolecular complex assembly 2.0214E-3 13 281 4 6292
    macromolecular complex subunit organization 4.8383E-3 13 357 4 6292
    cellular component assembly 6.3393E-3 13 385 4 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    RNA binding 4.5706E-5 13 367 6 6292
    rRNA binding 4.6527E-4 13 16 2 6292
    nucleic acid binding 1.2273E-3 13 666 6 6292
    ATP-dependent RNA helicase activity 1.4452E-3 13 28 2 6292
    RNA-dependent ATPase activity 1.5505E-3 13 29 2 6292
    RNA helicase activity 3.2387E-3 13 42 2 6292
    5S rRNA binding 4.1283E-3 13 2 1 6292
    ATP-dependent helicase activity 4.2134E-3 13 48 2 6292
    purine NTP-dependent helicase activity 4.2134E-3 13 48 2 6292
    binding 8.1545E-3 13 1294 7 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle