From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.533217104219] |
Complex Size: | 2 proteins |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
microtubule organizing center | 9.8679E-5 | 2 | 63 | 2 | 6292 |
spindle pole body | 9.8679E-5 | 2 | 63 | 2 | 6292 |
spindle pole | 1.151E-4 | 2 | 68 | 2 | 6292 |
spindle | 1.9786E-4 | 2 | 89 | 2 | 6292 |
microtubule cytoskeleton | 2.8118E-4 | 2 | 106 | 2 | 6292 |
cytoskeletal part | 1.0156E-3 | 2 | 201 | 2 | 6292 |
cytoskeleton | 1.1732E-3 | 2 | 216 | 2 | 6292 |
RENT complex | 1.2712E-3 | 2 | 4 | 1 | 6292 |
protein phosphatase type 2A complex | 1.9064E-3 | 2 | 6 | 1 | 6292 |
chromatin silencing complex | 2.859E-3 | 2 | 9 | 1 | 6292 |
protein serine/threonine phosphatase complex | 5.3968E-3 | 2 | 17 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
protein amino acid dephosphorylation | 1.9099E-5 | 2 | 28 | 2 | 6292 |
dephosphorylation | 3.9411E-5 | 2 | 40 | 2 | 6292 |
meiotic sister chromatid cohesion, centromeric | 3.1786E-4 | 2 | 1 | 1 | 6292 |
meiotic sister chromatid cohesion | 6.3568E-4 | 2 | 2 | 1 | 6292 |
phosphorus metabolic process | 1.3191E-3 | 2 | 229 | 2 | 6292 |
phosphate metabolic process | 1.3191E-3 | 2 | 229 | 2 | 6292 |
M phase | 2.1762E-3 | 2 | 294 | 2 | 6292 |
post-translational protein modification | 3.2108E-3 | 2 | 357 | 2 | 6292 |
cell cycle phase | 3.5621E-3 | 2 | 376 | 2 | 6292 |
meiotic chromosome segregation | 5.0798E-3 | 2 | 16 | 1 | 6292 |
cell cycle process | 6.0534E-3 | 2 | 490 | 2 | 6292 |
protein modification process | 6.278E-3 | 2 | 499 | 2 | 6292 |
cell cycle | 6.95E-3 | 2 | 525 | 2 | 6292 |
regulation of exit from mitosis | 7.9314E-3 | 2 | 25 | 1 | 6292 |
exit from mitosis | 7.9314E-3 | 2 | 25 | 1 | 6292 |
macromolecule modification | 8.1649E-3 | 2 | 569 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
phosphoprotein phosphatase activity | 4.5626E-5 | 2 | 43 | 2 | 6292 |
phosphatase activity | 1.8902E-4 | 2 | 87 | 2 | 6292 |
phosphoric ester hydrolase activity | 2.6026E-4 | 2 | 102 | 2 | 6292 |
protein phosphatase type 2A regulator activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
hydrolase activity, acting on ester bonds | 2.929E-3 | 2 | 341 | 2 | 6292 |
phosphatase regulator activity | 7.2981E-3 | 2 | 23 | 1 | 6292 |
protein phosphatase regulator activity | 7.2981E-3 | 2 | 23 | 1 | 6292 |
protein serine/threonine phosphatase activity | 8.248E-3 | 2 | 26 | 1 | 6292 |