From Publication: | Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054 |
Notes: | Classifier used Gene Ontology annotations. [FDR: 0.054] [SVM Score: 0.551548754995] |
Complex Size: | 2 proteins |
Protein |
GO Cellular Component | GO Biological Process | GO Molecular Function |
COX17 |
|
|
|
ISA2 |
|
|
|
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
mitochondrial intermembrane space | 3.1832E-5 | 2 | 36 | 2 | 6292 |
organelle envelope lumen | 3.9411E-5 | 2 | 40 | 2 | 6292 |
mitochondrial envelope | 2.4514E-3 | 2 | 312 | 2 | 6292 |
mitochondrial part | 5.6881E-3 | 2 | 475 | 2 | 6292 |
organelle envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
envelope | 6.43E-3 | 2 | 505 | 2 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
transition metal ion transport | 4.5626E-5 | 2 | 43 | 2 | 6292 |
metal ion transport | 8.3521E-5 | 2 | 58 | 2 | 6292 |
cation transport | 2.256E-4 | 2 | 95 | 2 | 6292 |
ion transport | 3.6076E-4 | 2 | 120 | 2 | 6292 |
intracellular copper ion transport | 1.5888E-3 | 2 | 5 | 1 | 6292 |
biotin metabolic process | 1.9064E-3 | 2 | 6 | 1 | 6292 |
amide biosynthetic process | 1.9064E-3 | 2 | 6 | 1 | 6292 |
biotin biosynthetic process | 1.9064E-3 | 2 | 6 | 1 | 6292 |
respiratory chain complex IV assembly | 2.5415E-3 | 2 | 8 | 1 | 6292 |
copper ion transport | 3.811E-3 | 2 | 12 | 1 | 6292 |
cellular amide metabolic process | 4.1283E-3 | 2 | 13 | 1 | 6292 |
iron ion transport | 5.7138E-3 | 2 | 18 | 1 | 6292 |
Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).
Only showing terms with a p-value less than or equal to 0.01.
GO Term |
P-value |
A |
B |
I |
T |
copper chaperone activity | 9.5344E-4 | 2 | 3 | 1 | 6292 |
metallochaperone activity | 1.2712E-3 | 2 | 4 | 1 | 6292 |
thioredoxin peroxidase activity | 2.859E-3 | 2 | 9 | 1 | 6292 |
copper ion binding | 2.859E-3 | 2 | 9 | 1 | 6292 |
peroxiredoxin activity | 2.859E-3 | 2 | 9 | 1 | 6292 |
peroxidase activity | 6.3477E-3 | 2 | 20 | 1 | 6292 |
oxidoreductase activity, acting on peroxide as acceptor | 6.3477E-3 | 2 | 20 | 1 | 6292 |
oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen | 7.2981E-3 | 2 | 23 | 1 | 6292 |
transition metal ion binding | 7.6148E-3 | 2 | 24 | 1 | 6292 |
antioxidant activity | 7.9314E-3 | 2 | 25 | 1 | 6292 |