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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.069] [SVM Score: 0.650832156998]
Complex Size: 2 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
MLP1
  • nuclear envelope
  • ribonucleoprotein complex
  • nucleoplasm
    		•
  • mRNA export from nucleus
  • protein import into nucleus
  • regulation of transcription
    		•
  • ribonucleoprotein binding
    		•
    SRP102
  • integral to endoplasmic reticulum membrane
  • signal recognition particle receptor complex
    		•
  • SRP-dependent cotranslational protein targeting to membrane
  • protein targeting to ER
    		•
  • GTP binding
  • GTPase activity
  • signal recognition particle binding
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    receptor complex 6.3568E-4 2 2 1 6292
    signal recognition particle receptor complex 6.3568E-4 2 2 1 6292
    rough endoplasmic reticulum 3.811E-3 2 12 1 6292
    rough endoplasmic reticulum membrane 3.811E-3 2 12 1 6292
    endomembrane system 3.9918E-3 2 398 2 6292
    integral to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292
    intrinsic to endoplasmic reticulum membrane 9.8303E-3 2 31 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    protein localization in organelle 5.5711E-4 2 149 2 6292
    protein targeting 1.3892E-3 2 235 2 6292
    intracellular protein transport 1.6363E-3 2 255 2 6292
    protein transport 1.8213E-3 2 269 2 6292
    establishment of protein localization 1.8485E-3 2 271 2 6292
    cellular protein localization 1.8898E-3 2 274 2 6292
    cellular macromolecule localization 2.0305E-3 2 284 2 6292
    protein localization 2.3118E-3 2 303 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    SRP-dependent cotranslational protein targeting to membrane 6.6645E-3 2 21 1 6292
    cotranslational protein targeting to membrane 7.6148E-3 2 24 1 6292
    intracellular transport 7.7118E-3 2 553 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    ribonucleoprotein binding 1.0611E-6 2 7 2 6292
    signal recognition particle binding 6.3568E-4 2 2 1 6292
    guanyl ribonucleotide binding 5.0798E-3 2 16 1 6292
    GTP binding 5.0798E-3 2 16 1 6292
    guanyl nucleotide binding 5.7138E-3 2 18 1 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle