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Protein Overview: SPAC22A12.16

General Information:
Name(s) found: SPAC22A12.16 [Sanger Pombe]
Description(s) found:
Found 19 descriptions.
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  • ATP-citrate synthase subunit 2 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 492 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDALink to PubMed article]
    cytoplasm [ISSLink to PubMed article]
    cytosol [IDALink to PubMed article]
    Biological Process: acetyl-CoA biosynthetic process [ISSLink to PubMed article]
    citrate metabolic process [ICLink to PubMed article]
    tricarboxylic acid cycle [ICLink to PubMed article]
    fatty acid biosynthetic process [ISSLink to PubMed article]
    Molecular Function: ATP binding [IEA]
    ATP citrate synthase activity [ISSLink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAKSIREYD GKAVLAYWLN RSPSISKEEY KTVSATPAVQ LAQIQFPLPT LVIPAESTTY  60
   61 REVVEDVFAK VEQEHPWVKE TKLVAKPDQL IKRRGKSGLL KLNATWDEAK EWIRERAGKN 120
  121 QKVQHAVGYL TTFLVEPFVP HPPNTEYYIN INSVREGDWI LFCNEGGVDV GDVDAKARKL 180
  181 LVPVRLSEFP SRATIASTLL SDIPVEQHES LVDFIIRLYS VYVDCQFTYL EINPLVVIPT 240
  241 AKGADVFYLD LAAKLDQTAE FECGAKWAVA RAPESLGIKT SGEESGAINA DHGPPMVFPA 300
  301 PFGRELSKEE AYVQGLDAKT GASLKLTILN AEGRVWNLVA GGGASVVYAD AVAVNGAADE 360
  361 LANYGEYSGA PTDGQTYEYA KTVLDLMTRG EPRADGKVLF IGGGIANFTS PAVTFRAIAR 420
  421 ALGDYKDKLH AHKVSIWVRR AGPNYQEGLR VIREAGKKFD LPLKVYGPEC HISGIVPMGL 480
  481 GKAPVEAEWQ MA

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

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    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..492] PSI-BLAST 98.69897 Succinyl-CoA synthetase, beta-chain, C-terminal domain; Succinyl-CoA synthetase, beta-chain, N-terminal domain

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • ATP citrate synthase activity
    		•  3.90324332109654 bayes_pls_golite062009
  • ligase activity, forming carbon-carbon bonds
    		•  3.81289459554571 bayes_pls_golite062009
  • CoA carboxylase activity
    		•  3.76609472018505 bayes_pls_golite062009
  • acetyl-CoA carboxylase activity
    		•  3.48441591588603 bayes_pls_golite062009
  • ligase activity
    		•  3.25077459445999 bayes_pls_golite062009
  • succinate-CoA ligase activity
    		•  3.09962677647723 bayes_pls_golite062009
  • catalytic activity
    		•  2.5009559386228 bayes_pls_golite062009
  • biotin carboxylase activity
    		•  2.20454959516404 bayes_pls_golite062009
  • ligase activity, forming carbon-sulfur bonds
    		•  2.11906303325597 bayes_pls_golite062009
  • succinate-CoA ligase (ADP-forming) activity
    		•  1.94897701568391 bayes_pls_golite062009
  • CoA-ligase activity
    		•  1.70650205723619 bayes_pls_golite062009
  • acid-thiol ligase activity
    		•  1.65304911485061 bayes_pls_golite062009
  • transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer
    		•  1.34604636411023 bayes_pls_golite062009
  • acid-amino acid ligase activity
    		•  0.942503524309464 bayes_pls_golite062009
  • ligase activity, forming carbon-nitrogen bonds
    		•  0.239594107637156 bayes_pls_golite062009
  • glutathione synthase activity
    		•  0.158287661667506 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.94

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle