YRC Public Data Repository - Protein Structure Prediction

Protein:	SPAC22A12.16
Organism:	Schizosaccharomyces pombe
Length:	492 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for SPAC22A12.16.

Description	E-value	Query Range	Subject Range
gi\|229329559, gi... - gi\|229499501\|ref\|ZP_04393185.1\| succinyl-CoA synthetase, beta subunit [Geobacillus sp. Y412MC52], gi... gi\|220708091, gi... - gi\|221088098\|ref\|ZP_03557632.1\| succinyl-CoA synthetase, beta subunit [Geobacillus sp. Y412MC61], gi... SUCC_GEOKA - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Geobacillus kaustophilus (strain HTA426) GN=sucC P... SUCC_GEOKA - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Geobacillus kaustophilus GN=sucC PE=3 SV=1	387.0	[0..41]	[477..1]
SUCC_BACHD - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus halodurans GN=sucC PE=3 SV=1 SUCC_BACHD - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus halodurans (strain ATCC BAA-125 / DSM 181...	382.0	[0..41]	[477..1]
gi\|89098658, gi\|... - gi\|89098658\|ref\|ZP_01171540.1\| succinyl-CoA synthetase subunit beta [Bacillus sp. NRRL B-14911], gi\|...	380.0	[0..41]	[477..1]
SUCC_BACLD - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus licheniformis (strain ATCC 14580 / DSM 13...	380.0	[0..41]	[477..1]
gi\|70992211, gi\|... - gi\|70992211\|ref\|XP_750954.1\| ATP citrate lyase subunit (Acl), putatibe [Aspergillus fumigatus Af293]...	378.0	[0..1]	[484..1]
SUCC_RHORT - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Rhodospirillum rubrum (strain ATCC 11170 / ATH 1.1... gi\|48764980 - ref\|ZP_00269531.1\| COG0045: Succinyl-CoA synthetase, beta subunit [Rhodospirillum rubrum]	377.0	[0..41]	[479..1]
SUCC_BACSU - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus subtilis GN=sucC PE=1 SV=2 SUCC_BACSU - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus subtilis (strain 168) GN=sucC PE=1 SV=2 gi\|221313809 - gi\|221313809\|ref\|ZP_03595614.1\| succinyl-CoA synthetase subunit beta [Bacillus subtilis subsp. subti... gi\|221318733 - gi\|221318733\|ref\|ZP_03600027.1\| succinyl-CoA synthetase subunit beta [Bacillus subtilis subsp. subti... gi\|221323004 - gi\|221323004\|ref\|ZP_03604298.1\| succinyl-CoA synthetase subunit beta [Bacillus subtilis subsp. subti...	377.0	[0..41]	[476..1]
SUCC_BACAC - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus anthracis (strain CDC 684 / NRRL 3495) GN... gi\|170125736, gi... - gi\|170709362\|ref\|ZP_02899776.1\| succinate-CoA ligase (ADP-forming), beta subunit [Bacillus anthracis... gi\|172079897, gi... - gi\|177655998\|ref\|ZP_02937125.1\| succinate-CoA ligase (ADP-forming), beta subunit [Bacillus anthracis... SUCC_BACAN - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus anthracis GN=sucC PE=3 SV=1 gi\|47504412, gi\|... - gi\|47529264\|ref\|YP_020613.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. 'Ames Anc... gi\|30263839, gi\|... - gi\|30263839\|ref\|NP_846216.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. Ames], gi... gi\|65321163, gi\|... - gi\|65321163\|ref\|ZP_00394122.1\| COG0045: Succinyl-CoA synthetase, beta subunit [Bacillus anthracis st... gi\|164710949, gi... - gi\|165873311\|ref\|ZP_02217916.1\| succinate-CoA ligase (ADP-forming), beta subunit [Bacillus anthracis... gi\|167510013, gi... - gi\|167642033\|ref\|ZP_02400263.1\| succinate-CoA ligase (ADP-forming), beta subunit [Bacillus anthracis... gi\|49186686, gi\|... - gi\|49186686\|ref\|YP_029938.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. Sterne], ... gi\|170666386, gi... - gi\|170689662\|ref\|ZP_02880842.1\| succinate-CoA ligase (ADP-forming), beta subunit [Bacillus anthracis... gi\|254751205 - gi\|254751205\|ref\|ZP_05203244.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. Vollum... gi\|254739601 - gi\|254739601\|ref\|ZP_05197295.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. Kruger... gi\|254735874 - gi\|254735874\|ref\|ZP_05193580.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. Wester... gi\|254721978 - gi\|254721978\|ref\|ZP_05183767.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. A1055] gi\|254683457 - gi\|254683457\|ref\|ZP_05147317.1\| succinyl-CoA synthetase subunit beta [Bacillus anthracis str. CNEVA-... SUCC_BACAA - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus anthracis (strain A0248) GN=sucC PE=3 SV=...	376.0	[0..41]	[477..1]
gi\|23098998, gi\|... - gi\|23098998\|ref\|NP_692464.1\| succinyl-CoA synthetase subunit beta [Oceanobacillus iheyensis HTE831],...	376.0	[0..41]	[477..1]
gi\|228986979, gi... - gi\|228986979\|ref\|ZP_04147105.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus thuringiens... gi\|228812075, gi... - gi\|228947555\|ref\|ZP_04109845.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus thuringiens... gi\|229123350, gi... - gi\|229123350\|ref\|ZP_04252554.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus cereus 95/8... gi\|229092878, gi... - gi\|229092878\|ref\|ZP_04224012.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus cereus Rock... gi\|228597252, gi... - gi\|229186076\|ref\|ZP_04313245.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus cereus BGSC... gi\|229140478, gi... - gi\|229140478\|ref\|ZP_04269033.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus cereus BDRD... gi\|229197946, gi... - gi\|229197946\|ref\|ZP_04324661.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus cereus m129... gi\|47553002, gi\|... - gi\|47570337\|ref\|ZP_00240982.1\| succinyl-CoA synthetase beta chain [Bacillus cereus G9241], gi\|475530... SUCC_BACHK - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus thuringiensis subsp. konkukian GN=sucC PE... SUCC_BACCZ - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus cereus (strain ZK / E33L) GN=sucC PE=3 SV... SUCC_BACC7 - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus cereus (strain AH187) GN=sucC PE=3 SV=1 SUCC_BACAH - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus thuringiensis (strain Al Hakam) GN=sucC P... SUCC_BACCQ - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus cereus (strain Q1) GN=sucC PE=3 SV=1 SUCC_BACC1 - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus cereus (strain ATCC 10987 / NRS 248) GN=s... SUCC_BACHK - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus thuringiensis subsp. konkukian (strain 97... SUCC_BACC3 - Succinyl-CoA ligase [ADP-forming] subunit beta OS=Bacillus cereus (strain 03BB102) GN=sucC PE=3 SV=1 gi\|228935150, gi... - gi\|228935150\|ref\|ZP_04097977.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus thuringiens... gi\|228843052, gi... - gi\|228916473\|ref\|ZP_04080039.1\| Succinyl-CoA ligase [ADP-forming] subunit beta [Bacillus thuringiens...	376.0	[0..41]	[477..1]

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Predicted Domain #1

Region A:
Residues: [1-492]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSAKSIREYD GKAVLAYWLN RSPSISKEEY KTVSATPAVQ LAQIQFPLPT LVIPAESTTY  60
   61 REVVEDVFAK VEQEHPWVKE TKLVAKPDQL IKRRGKSGLL KLNATWDEAK EWIRERAGKN 120
  121 QKVQHAVGYL TTFLVEPFVP HPPNTEYYIN INSVREGDWI LFCNEGGVDV GDVDAKARKL 180
  181 LVPVRLSEFP SRATIASTLL SDIPVEQHES LVDFIIRLYS VYVDCQFTYL EINPLVVIPT 240
  241 AKGADVFYLD LAAKLDQTAE FECGAKWAVA RAPESLGIKT SGEESGAINA DHGPPMVFPA 300
  301 PFGRELSKEE AYVQGLDAKT GASLKLTILN AEGRVWNLVA GGGASVVYAD AVAVNGAADE 360
  361 LANYGEYSGA PTDGQTYEYA KTVLDLMTRG EPRADGKVLF IGGGIANFTS PAVTFRAIAR 420
  421 ALGDYKDKLH AHKVSIWVRR AGPNYQEGLR VIREAGKKFD LPLKVYGPEC HISGIVPMGL 480
  481 GKAPVEAEWQ MA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	98.69897
Match:	1jkjB
Description:	Succinyl-CoA synthetase, beta-chain, C-terminal domain; Succinyl-CoA synthetase, beta-chain, N-terminal domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
ATP citrate synthase activity	3.90324332109654	bayes_pls_golite062009
ligase activity, forming carbon-carbon bonds	3.81289459554571	bayes_pls_golite062009
CoA carboxylase activity	3.76609472018505	bayes_pls_golite062009
acetyl-CoA carboxylase activity	3.48441591588603	bayes_pls_golite062009
ligase activity	3.25077459445999	bayes_pls_golite062009
succinate-CoA ligase activity	3.09962677647723	bayes_pls_golite062009
catalytic activity	2.5009559386228	bayes_pls_golite062009
biotin carboxylase activity	2.20454959516404	bayes_pls_golite062009
ligase activity, forming carbon-sulfur bonds	2.11906303325597	bayes_pls_golite062009
succinate-CoA ligase (ADP-forming) activity	1.94897701568391	bayes_pls_golite062009
CoA-ligase activity	1.70650205723619	bayes_pls_golite062009
acid-thiol ligase activity	1.65304911485061	bayes_pls_golite062009
transferase activity, transferring acyl groups, acyl groups converted into alkyl on transfer	1.34604636411023	bayes_pls_golite062009
acid-amino acid ligase activity	0.942503524309464	bayes_pls_golite062009
ligase activity, forming carbon-nitrogen bonds	0.239594107637156	bayes_pls_golite062009
glutathione synthase activity	0.158287661667506	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: