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Protein Overview: rnc1

General Information:
Name(s) found: rnc1 / SPCC757.09c [Sanger Pombe]
Description(s) found:
Found 18 descriptions.
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  • RNA-binding protein that suppresses calcineurin deletion Rnc1 [Sanger Pombe]
    • Organism: Schizosaccharomyces pombe
    Length: 398 amino acids

    Gene Ontology:
    Cellular Component: cytosol [IDALink to PubMed article]
    Biological Process: negative regulation of MAPKKK cascade [IGILink to PubMed article]
    mRNA stabilization [IMPLink to PubMed article]
    negative regulation of protein kinase activity [IGILink to PubMed article]
    Molecular Function: protein binding [IPILink to PubMed article]
    mRNA binding [IPILink to PubMed article]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAYNHFSIPK NIEEKENSFF DVTFQDEPDE TTSTATGIAK VSIPTPKPST PLSTLTNGST  60
   61 IQQSMTNQPE PTSQVPPISA KPPMDDATYA TQQLTLRALL STREAGIIIG KAGKNVAELR 120
  121 STTNVKAGVT KAVPNVHDRV LTISGPLENV VRAYRFIIDI FAKNSTNPDG TPSDANTPRK 180
  181 LRLLIAHSLM GSIIGRNGLR IKLIQDKCSC RMIASKDMLP QSTERTVEIH GTVDNLHAAI 240
  241 WEIGKCLIDD WERGAGTVFY NPVSRLTQPL PSLASTASPQ QVSPPAAPST TSGEAIPENF 300
  301 VSYGAQVFPA TQMPFLQQPK VTQNISIPAD MVGCIIGRGG SKISEIRRTS GSKISIAKEP 360
  361 HDETGERMFT ITGTHEENEK ALFLLYQQLE MEKDRRSH

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..254] PSI-BLAST 29.522879 Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 3; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 1 and 4; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domain 6; Polynucleotide phosphorylase/guanosine pentaphosphate synthase (PNPase/GPSI), domains 2 and 5
    2 View Details [255..398] PSI-BLAST 15.0 Crsytal Structure of domain 3 of human alpha polyC binding protein

    Functions predicted (by domain):

    # Gene Ontology predictions
    1
    Term Confidence Notes
  • telomeric DNA binding
    		•  7.07761964836826 bayes_pls_golite062009
  • single-stranded telomeric DNA binding
    		•  6.40125558525939 bayes_pls_golite062009
  • telomerase inhibitor activity
    		•  5.75006730667111 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.09002897694881 bayes_pls_golite062009
  • structural constituent of ribosome
    		•  3.63349555627235 bayes_pls_golite062009
  • structural molecule activity
    		•  3.43604616110432 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  3.06066809614422 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  3.0183551365402 bayes_pls_golite062009
  • nucleic acid binding
    		•  2.55336640491561 bayes_pls_golite062009
  • RNA binding
    		•  2.47373172667773 bayes_pls_golite062009
  • binding
    		•  1.9759530321894 bayes_pls_golite062009
  • DNA binding
    		•  1.83809666640016 bayes_pls_golite062009
  • translation regulator activity
    		•  1.46320772716954 bayes_pls_golite062009
  • translation factor activity, nucleic acid binding
    		•  1.40718318783582 bayes_pls_golite062009
  • transcription factor activity
    		•  1.21526211005888 bayes_pls_golite062009
    		• 1.2099360907571 bayes_pls_golite062009
  • ribonuclease activity
    		•  1.19236946227657 bayes_pls_golite062009
  • DNA helicase activity
    		•  1.12203697857261 bayes_pls_golite062009
  • 3'-5'-exoribonuclease activity
    		•  1.11755548907336 bayes_pls_golite062009
  • transcription termination factor activity
    		•  1.01993495617192 bayes_pls_golite062009
  • translation initiation factor activity
    		•  0.96756670903925 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.85691075793641 bayes_pls_golite062009
  • DEAD/H-box RNA helicase binding
    		•  0.772325293846201 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.638831894247026 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  0.635129001787169 bayes_pls_golite062009
  • protein binding
    		•  0.523813050066193 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  0.491028860958185 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
    		•  0.474251377131502 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
    		•  0.47336621289748 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
    		•  0.47336621289748 bayes_pls_golite062009
  • mRNA binding
    		•  0.403794675006504 bayes_pls_golite062009
  • DNA-(apurinic or apyrimidinic site) lyase activity
    		•  0.288026663667102 bayes_pls_golite062009
  • exonuclease activity
    		•  0.28313884527829 bayes_pls_golite062009
  • transferase activity
    		•  0.249054945579328 bayes_pls_golite062009
  • exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters
    		•  0.19873212905058 bayes_pls_golite062009
  • damaged DNA binding
    		•  0.16864489654021 bayes_pls_golite062009
  • exoribonuclease activity, producing 5'-phosphomonoesters
    		•  0.125256208482441 bayes_pls_golite062009
  • exoribonuclease activity
    		•  0.109774918833391 bayes_pls_golite062009
  • RNA polymerase activity
    		•  0.10868826895563 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  0.10868826895563 bayes_pls_golite062009
  • catalytic activity
    		•  0.10089766806364 bayes_pls_golite062009
  • transcription factor binding
    		•  0.0560158842173433 bayes_pls_golite062009
  • ATP-dependent DNA helicase activity
    		•  0.0179535526984695 bayes_pls_golite062009
  • helicase activity
    		•  0.0121541775159524 bayes_pls_golite062009
    2
    Term Confidence Notes
  • RNA binding
    		•  5.18414740305744 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.78650555542715 bayes_pls_golite062009
  • mRNA binding
    		•  3.82977088614136 bayes_pls_golite062009
  • binding
    		•  3.45962790790935 bayes_pls_golite062009
  • transcription regulator activity
    		•  2.28364833275102 bayes_pls_golite062009
  • DNA binding
    		•  2.03207983673692 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  1.56764875690146 bayes_pls_golite062009
  • single-stranded DNA binding
    		•  1.49537687514752 bayes_pls_golite062009
  • transcription factor activity
    		•  1.30278154718684 bayes_pls_golite062009
    		• 1.27314120901993 bayes_pls_golite062009
  • protein binding
    		•  1.16541072642796 bayes_pls_golite062009
  • mRNA 3'-UTR binding
    		•  0.722090816226222 bayes_pls_golite062009
  • transcription repressor activity
    		•  0.392035003865213 bayes_pls_golite062009
  • transcription activator activity
    		•  0.324382863054631 bayes_pls_golite062009
  • transcription factor binding
    		•  0.254024117548226 bayes_pls_golite062009
  • catalytic activity
    		•  0.113112541746059 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  0.0321875054165348 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.97

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle