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Protein Overview: cdk9

Protein Complex Data

No complex found for this protein.

Mass Spectrometry Data

No mass spectrometry results found for this protein.

Yeast Two-Hybrid Data

The following interactions contain this protein:

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[View our yeast two-hybrid interpretation guidelines.]

No yeast two-hybrid interactions found for this protein.

Microscopy / Localization Data

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No microscopy data found in the PDR for this protein.

Protein Structure Data


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[View Top Sequence Alignments] [Show Ginzu Version Information]

Domains predicted:

#   Region(s) Method Confidence Match Description
1 View Details [1..379] PSI-BLAST 81.39794 Structure of CDK2/Cyclin A with PNU-292137
2 View Details [380..591] deduced N/A No confident structure predictions are available.

Functions predicted (by domain):

# Gene Ontology predictions
1
Term Confidence Notes
  • acetylcholine receptor activator activity
  • 5.9159846946654 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
  • 5.68265749805481 bayes_pls_golite062009
  • phosphotransferase activity, alcohol group as acceptor
  • 5.49988294224815 bayes_pls_golite062009
  • protein kinase activity
  • 5.4586557943719 bayes_pls_golite062009
  • kinase activity
  • 5.3287080791198 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
  • 4.96052051118534 bayes_pls_golite062009
  • transcription elongation regulator activity
  • 4.93646793786886 bayes_pls_golite062009
  • cyclin-dependent protein kinase activity
  • 4.62392503670521 bayes_pls_golite062009
  • protein serine/threonine kinase activity
  • 4.46381887831481 bayes_pls_golite062009
  • transferase activity
  • 3.97138602499442 bayes_pls_golite062009
  • structural molecule activity
  • 3.82327979736517 bayes_pls_golite062009
  • transmembrane receptor protein tyrosine kinase activity
  • 3.41480681854114 bayes_pls_golite062009
  • transmembrane receptor protein kinase activity
  • 3.40140621607334 bayes_pls_golite062009
  • MAP kinase 2 activity
  • 3.27009208121248 bayes_pls_golite062009
  • protein tyrosine kinase activity
  • 2.8153155526437 bayes_pls_golite062009
  • phosphoinositide 3-kinase binding
  • 2.79505438761262 bayes_pls_golite062009
  • binding
  • 2.74863538127007 bayes_pls_golite062009
  • transmembrane receptor activity
  • 2.59526003830791 bayes_pls_golite062009
  • ion transmembrane transporter activity
  • 2.52531786618214 bayes_pls_golite062009
  • cation transmembrane transporter activity
  • 2.46424348876434 bayes_pls_golite062009
  • signal transducer activity
  • 2.40586892801446 bayes_pls_golite062009
  • molecular transducer activity
  • 2.40586892801446 bayes_pls_golite062009
  • receptor activity
  • 2.39311927684508 bayes_pls_golite062009
  • substrate-specific transmembrane transporter activity
  • 2.37122853419919 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase activity
  • 2.30873410607588 bayes_pls_golite062009
  • transforming growth factor beta receptor activity
  • 2.30873410607588 bayes_pls_golite062009
  • histone kinase activity (H3-S10 specific)
  • 2.30449166929476 bayes_pls_golite062009
  • protein binding
  • 2.276111749106 bayes_pls_golite062009
  • tubulin binding
  • 2.18641675163967 bayes_pls_golite062009
  • cytoskeletal protein binding
  • 2.12615078788254 bayes_pls_golite062009
  • receptor signaling protein activity
  • 2.10379226653669 bayes_pls_golite062009
  • ATP binding
  • 1.97600611746091 bayes_pls_golite062009
  • ubiquitin-protein ligase activity
  • 1.94085498993561 bayes_pls_golite062009
  • adenyl ribonucleotide binding
  • 1.93596671856664 bayes_pls_golite062009
  • adenyl nucleotide binding
  • 1.90928021591891 bayes_pls_golite062009
  • metal ion transmembrane transporter activity
  • 1.9016235206634 bayes_pls_golite062009
  • microtubule binding
  • 1.88110801192607 bayes_pls_golite062009
  • actin binding
  • 1.87817875565699 bayes_pls_golite062009
  • receptor signaling protein serine/threonine kinase activity
  • 1.81249386965144 bayes_pls_golite062009
  • telethonin binding
  • 1.75733591474207 bayes_pls_golite062009
  • transforming growth factor beta receptor activity, type I
  • 1.74645334586495 bayes_pls_golite062009
  • small conjugating protein ligase activity
  • 1.74206248731815 bayes_pls_golite062009
  • activin binding
  • 1.69795678545106 bayes_pls_golite062009
  • fibroblast growth factor 1 binding
  • 1.66976264488423 bayes_pls_golite062009
  • purine ribonucleotide binding
  • 1.65732943334212 bayes_pls_golite062009
  • ribonucleotide binding
  • 1.65726906484847 bayes_pls_golite062009
  • activin receptor activity
  • 1.64506335968643 bayes_pls_golite062009
  • purine nucleotide binding
  • 1.63763394711025 bayes_pls_golite062009
  • nucleotide binding
  • 1.63195828048121 bayes_pls_golite062009
  • insulin receptor substrate binding
  • 1.62657794525303 bayes_pls_golite062009
  • JUN kinase kinase kinase activity
  • 1.60259443694567 bayes_pls_golite062009
  • transcription regulator activity
  • 1.56748951434625 bayes_pls_golite062009
  • growth factor binding
  • 1.53863828216563 bayes_pls_golite062009
  • nucleic acid binding
  • 1.46547714006072 bayes_pls_golite062009
  • MAP kinase kinase activity
  • 1.42275431028856 bayes_pls_golite062009
  • DNA binding
  • 1.35333135345112 bayes_pls_golite062009
  • ErbB-3 class receptor binding
  • 1.34841233233438 bayes_pls_golite062009
  • ErbB-2 class receptor binding
  • 1.33825339298024 bayes_pls_golite062009
  • kinase binding
  • 1.26086833316556 bayes_pls_golite062009
  • acid-amino acid ligase activity
  • 1.2266791546014 bayes_pls_golite062009
  • catalytic activity
  • 1.21655087018101 bayes_pls_golite062009
  • transcription repressor activity
  • 1.14496167267281 bayes_pls_golite062009
  • transporter activity
  • 1.11833481501707 bayes_pls_golite062009
  • non-membrane spanning protein tyrosine kinase activity
  • 1.11664317075762 bayes_pls_golite062009
  • transcription factor activity
  • 1.10928254946881 bayes_pls_golite062009
  • protein kinase binding
  • 1.06030596516506 bayes_pls_golite062009
  • cation channel activity
  • 1.04999722123563 bayes_pls_golite062009
  • type II transforming growth factor beta receptor binding
  • 1.03605423743048 bayes_pls_golite062009
  • SMAD binding
  • 1.02108562119195 bayes_pls_golite062009
  • transcription activator activity
  • 0.997272622653026 bayes_pls_golite062009
  • PTB domain binding
  • 0.9900774724568 bayes_pls_golite062009
  • transmembrane transporter activity
  • 0.97575992765505 bayes_pls_golite062009
  • alpha-actinin binding
  • 0.877087652539674 bayes_pls_golite062009
  • insulin-like growth factor receptor binding
  • 0.872782211382796 bayes_pls_golite062009
  • fibroblast growth factor binding
  • 0.870666814073948 bayes_pls_golite062009
  • activin receptor activity, type I
  • 0.82317428935631 bayes_pls_golite062009
  • MAP kinase activity
  • 0.81943579965027 bayes_pls_golite062009
  • actin filament binding
  • 0.794152600084 bayes_pls_golite062009
  • fibroblast growth factor receptor activity
  • 0.75189004129952 bayes_pls_golite062009
  • receptor serine/threonine kinase binding
  • 0.728917900114111 bayes_pls_golite062009
  • substrate-specific transporter activity
  • 0.705905455086486 bayes_pls_golite062009
  • transforming growth factor beta receptor binding
  • 0.705634826374884 bayes_pls_golite062009
  • transmembrane receptor protein serine/threonine kinase binding
  • 0.705634826374884 bayes_pls_golite062009
  • hormone receptor binding
  • 0.705067960165986 bayes_pls_golite062009
  • beta-catenin binding
  • 0.693246095477001 bayes_pls_golite062009
  • structural constituent of cytoskeleton
  • 0.612883428421652 bayes_pls_golite062009
  • cyclin-dependent protein kinase activating kinase activity
  • 0.529121666062889 bayes_pls_golite062009
  • steroid hormone receptor binding
  • 0.505233004492768 bayes_pls_golite062009
  • protein serine/threonine/tyrosine kinase activity
  • 0.48345772948903 bayes_pls_golite062009
  • enzyme binding
  • 0.46284745266176 bayes_pls_golite062009
  • transforming growth factor beta binding
  • 0.435457844706269 bayes_pls_golite062009
  • protein kinase C activity
  • 0.41587987561486 bayes_pls_golite062009
  • cyclin-dependent protein kinase regulator activity
  • 0.406297251827056 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
  • 0.401250804041384 bayes_pls_golite062009
  • structural constituent of muscle
  • 0.399773397398032 bayes_pls_golite062009
  • magnesium ion binding
  • 0.393328812780268 bayes_pls_golite062009
  • MAP kinase kinase kinase activity
  • 0.37115026509016 bayes_pls_golite062009
  • structure-specific DNA binding
  • 0.318153468064373 bayes_pls_golite062009
  • channel activity
  • 0.287189255116606 bayes_pls_golite062009
  • passive transmembrane transporter activity
  • 0.287189255116606 bayes_pls_golite062009
  • insulin receptor binding
  • 0.266450215230107 bayes_pls_golite062009
  • substrate-specific channel activity
  • 0.261869836686301 bayes_pls_golite062009
  • RNA binding
  • 0.245748631571068 bayes_pls_golite062009
  • ion channel activity
  • 0.241519346930618 bayes_pls_golite062009
  • nuclear hormone receptor binding
  • 0.240883589532225 bayes_pls_golite062009
  • protein complex binding
  • 0.239339759110451 bayes_pls_golite062009
  • insulin receptor activity
  • 0.237134032032089 bayes_pls_golite062009
  • SH2 domain binding
  • 0.226760162354251 bayes_pls_golite062009
  • ligase activity, forming carbon-oxygen bonds
  • 0.149958560815481 bayes_pls_golite062009
  • ligase activity, forming aminoacyl-tRNA and related compounds
  • 0.149958560815481 bayes_pls_golite062009
  • aminoacyl-tRNA ligase activity
  • 0.14842991990838 bayes_pls_golite062009
  • peptide binding
  • 0.118578378753757 bayes_pls_golite062009
  • brain-derived neurotrophic factor binding
  • 0.0794053647730006 bayes_pls_golite062009
  • nitric-oxide synthase regulator activity
  • 0.00407218246327123 bayes_pls_golite062009
  • nucleoside-triphosphatase activity
  • 0.0040394359628233 bayes_pls_golite062009
    2 No functions predicted.




    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.99

    Source: Reynolds et al. (2008)


    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle