YRC Public Data Repository - Protein Structure Prediction

Protein:	CYDC_ECOLI
Organism:	Escherichia coli
Length:	573 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for CYDC_ECOLI.

Description	E-value	Query Range	Subject Range
gi\|110800402, gi... - gi\|110800402\|ref\|YP_694961.1\| ABC transporter, permease/ATP-binding protein [Clostridium perfringens...	526.0	[0..3]	[570..32]
gi\|110682877, gi... - gi\|110802376\|ref\|YP_697823.1\| uncharacterized ABC transporter, ATPase component [Clostridium perfrin...	525.0	[0..3]	[570..32]
gi\|18309509, gi\|... - gi\|18309509\|ref\|NP_561443.1\| ABC transporter [Clostridium perfringens str. 13], gi\|18144186\|dbj\|BAB8...	524.0	[0..3]	[570..32]
Y288_THEMA - Uncharacterized ABC transporter ATP-binding protein TM_0288 OS=Thermotoga maritima GN=TM_0288 PE=3 S... Y288_THEMA - Uncharacterized ABC transporter ATP-binding protein TM_0288 OS=Thermotoga maritima (strain ATCC 4358...	524.0	[0..3]	[569..24]
gi\|20807317, gi\|... - gi\|20807317\|ref\|NP_622488.1\| ABC-type multidrug/protein/lipid transport system, ATPase component [Th... gi\|20807317 - gi\|20807317\|ref\|NP_622488.1\| ABC-type multidrug/protein/lipid transport system, ATPase component [Th...	520.0	[0..2]	[570..16]
MSBA_SYNAS - Lipid A export ATP-binding/permease protein MsbA OS=Syntrophus aciditrophicus (strain SB) GN=msbA PE...	516.0	[0..1]	[571..18]
gi\|1673392, gi\|7... - pir\|\|G69815 ABC transporter (ATP-binding protein) homolog ygaD - Bacillus subtilis, gi\|1673392\|emb\|C... gi\|16077935, gi\|... - gi\|2633192\|emb\|CAB12697.1\| putative ABC transporter (ATP-binding protein) [Bacillus subtilis subsp. ...	516.0	[0..3]	[569..12]
gi\|30248923, gi\|... - gi\|30248923\|ref\|NP_840993.1\| ABC transporter permease/ATP-binding protein [Nitrosomonas europaea ATC...	515.0	[0..2]	[571..164]
gi\|88914203, gi\|... - gi\|88933337\|ref\|ZP_01139016.1\| ABC transporter, transmembrane region:ABC transporter related [Dehalo...	515.0	[0..3]	[570..48]
gi\|160427679, gi... - gi\|160879013\|ref\|YP_001557981.1\| ABC transporter related [Clostridium phytofermentans ISDg], gi\|1604...	515.0	[0..3]	[570..40]

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Predicted Domain #1

Region A:
Residues: [1-573]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRALLPYLAL YKRHKWMLSL GIVLAIVTLL ASIGLLTLSG WFLSASAVAG VAGLYSFNYM  60
   61 LPAAGVRGAA ITRTAGRYFE RLVSHDATFR VLQHLRIYTF SKLLPLSPAG LARYRQGELL 120
  121 NRVVADVDTL DHLYLRVISP LVGAFVVIMV VTIGLSFLDF TLAFTLGGIM LLTLFLMPPL 180
  181 FYRAGKSTGQ NLTHLRGQYR QQLTAWLQGQ AELTIFGASD RYRTQLENTE IQWLEAQRRQ 240
  241 SELTALSQAI MLLIGALAVI LMLWMASGGV GGNAQPGALI ALFVFCALAA FEALAPVTGA 300
  301 FQHLGQVIAS AVRISDLTDQ KPEVTFPDTQ TRVADRVSLT LRDVQFTYPE QSQQALKGIS 360
  361 LQVNAGEHIA ILGRTGCGKS TLLQQLTRAW DPQQGEILLN DSPIASLNEA ALRQTISVVP 420
  421 QRVHLFSATL RDNLLLASPG SSDEALSEIL RRVGLEKLLE DAGLNSWLGE GGRQLSGGEL 480
  481 RRLAIARALL HDAPLVLLDE PTEGLDATTE SQILELLAEM MREKTVLMVT HRLRGLSRFQ 540
  541 QIIVMDNGQI IEQGTHAELL ARQGRYYQFK QGL

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	140.0
Match:	2hydA
Description:	No description for 2hydA was found.

Predicted functions:

Term	Confidence	Notes
lipid transporter activity	7.47642599298853	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	5.57844095962502	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	5.57813579764186	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	5.57813579764186	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	5.5689620139321	bayes_pls_golite062009
primary active transmembrane transporter activity	5.55992639965745	bayes_pls_golite062009
active transmembrane transporter activity	5.50005167063544	bayes_pls_golite062009
ATPase activity, coupled	4.98276715440477	bayes_pls_golite062009
heme transporter activity	4.82479229680991	bayes_pls_golite062009
peptide transporter activity	4.7442815698413	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	4.71935767060308	bayes_pls_golite062009
ATPase activity	4.69795387297193	bayes_pls_golite062009
peptide-transporting ATPase activity	4.63590351019108	bayes_pls_golite062009
nucleoside-triphosphatase activity	4.45923622153365	bayes_pls_golite062009
pyrophosphatase activity	4.39781350157199	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	4.38133275795019	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	4.38085303582726	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	4.35344629015015	bayes_pls_golite062009
oligopeptide-transporting ATPase activity	4.09365342567844	bayes_pls_golite062009
transporter activity	3.71239480053329	bayes_pls_golite062009
cofactor transporter activity	3.63426880082372	bayes_pls_golite062009
hydrogen ion transporting ATP synthase activity, rotational mechanism	3.57926427233638	bayes_pls_golite062009
ion transmembrane transporter activity	3.35436118751376	bayes_pls_golite062009
phosphate transmembrane-transporting ATPase activity	3.20894563245332	bayes_pls_golite062009
hydrolase activity	3.14498892233323	bayes_pls_golite062009
phosphate transmembrane transporter activity	3.14373643903738	bayes_pls_golite062009
transmembrane transporter activity	3.13960906549884	bayes_pls_golite062009
anion transmembrane transporter activity	3.13913638619234	bayes_pls_golite062009
substrate-specific transporter activity	3.1318898376276	bayes_pls_golite062009
cation transmembrane transporter activity	3.08390071341252	bayes_pls_golite062009
iron ion transmembrane transporter activity	3.05511942104215	bayes_pls_golite062009
ATP binding	3.01346604299372	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	3.00745742755195	bayes_pls_golite062009
drug transmembrane transporter activity	2.97119034312001	bayes_pls_golite062009
adenyl ribonucleotide binding	2.96271391116269	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	2.9271291809464	bayes_pls_golite062009
adenyl nucleotide binding	2.91131545957759	bayes_pls_golite062009
branched-chain aliphatic amino acid transmembrane transporter activity	2.88795687640992	bayes_pls_golite062009
metal ion transmembrane transporter activity	2.88476360771975	bayes_pls_golite062009
purine ribonucleotide binding	2.70262534541085	bayes_pls_golite062009
ribonucleotide binding	2.70178191749524	bayes_pls_golite062009
amine-transporting ATPase activity	2.69529191205818	bayes_pls_golite062009
organic acid transmembrane transporter activity	2.67957846350199	bayes_pls_golite062009
carboxylic acid transmembrane transporter activity	2.67815672695824	bayes_pls_golite062009
purine nucleotide binding	2.6583477492092	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	2.63419811368692	bayes_pls_golite062009
nucleotide binding	2.62374702628143	bayes_pls_golite062009
sterol transporter activity	2.48473697371886	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	2.40292717311506	bayes_pls_golite062009
amine transmembrane transporter activity	2.29486577878686	bayes_pls_golite062009
	2.20174656498665	bayes_pls_golite062009
oligopeptide transporter activity	2.05580564974083	bayes_pls_golite062009
molybdate transmembrane-transporting ATPase activity	2.04724145339382	bayes_pls_golite062009
molybdate ion transmembrane transporter activity	2.04724145339382	bayes_pls_golite062009
transition metal ion transmembrane transporter activity	1.82177108193332	bayes_pls_golite062009
protein transporter activity	1.71214667007262	bayes_pls_golite062009
potassium channel activity	1.68725597823541	bayes_pls_golite062009
amino acid transmembrane transporter activity	1.59627719545436	bayes_pls_golite062009
binding	1.39093533263371	bayes_pls_golite062009
manganese ion transmembrane transporter activity	1.34412762758893	bayes_pls_golite062009
cation channel activity	1.33585529285301	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of ions	1.23799860254751	bayes_pls_golite062009
sulfate transmembrane-transporting ATPase activity	1.1220946941463	bayes_pls_golite062009
GTPase activity	1.05341575831759	bayes_pls_golite062009
manganese-transporting ATPase activity	1.05250190312265	bayes_pls_golite062009
dipeptide transporter activity	1.01130176523309	bayes_pls_golite062009
voltage-gated cation channel activity	1.00384984515681	bayes_pls_golite062009
sulfur amino acid transmembrane transporter activity	0.993585129677597	bayes_pls_golite062009
voltage-gated ion channel activity	0.889208591820696	bayes_pls_golite062009
voltage-gated channel activity	0.871525745291603	bayes_pls_golite062009
ion channel activity	0.848261056209476	bayes_pls_golite062009
passive transmembrane transporter activity	0.806331380134838	bayes_pls_golite062009
channel activity	0.806331380134838	bayes_pls_golite062009
substrate-specific channel activity	0.799997700906738	bayes_pls_golite062009
copper ion transmembrane transporter activity	0.798934081014025	bayes_pls_golite062009
di-, tri-valent inorganic cation transmembrane transporter activity	0.767424210804186	bayes_pls_golite062009
gated channel activity	0.650050847753837	bayes_pls_golite062009
cholesterol transporter activity	0.644421039250979	bayes_pls_golite062009
guanyl nucleotide binding	0.640772201693186	bayes_pls_golite062009
guanyl ribonucleotide binding	0.63468044350616	bayes_pls_golite062009
GTP binding	0.621689261700018	bayes_pls_golite062009
L-aspartate transmembrane transporter activity	0.483217496906356	bayes_pls_golite062009
neutral amino acid transmembrane transporter activity	0.227570438294493	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	0.219473333671469	bayes_pls_golite062009
signal recognition particle binding	0.20866768220789	bayes_pls_golite062009
amino acid-transporting ATPase activity	0.147644650870465	bayes_pls_golite062009
cation-transporting ATPase activity	0.0536898657672154	bayes_pls_golite062009
motor activity	0.0492636236578701	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: