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Primary active transport of a solute across a membrane, driven by the hydrolysis of the diphosphate bond of inorganic pyrophosphate, ATP, or another nucleoside triphosphate. The transport protein may or may not be transiently phosphorylated, but the substrate is not phosphorylated. Primary active transport is catalysis of the transport of a solute across a membrane, up the solute's concentration gradient, by binding the solute and undergoing a series of conformational changes. Transport works equally well in either direction and is driven by a primary energy source. Enables the directed movement of a specific substance or group of related substances (such as macromolecules, small molecules, ions) into, out of, within or between cells. Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the active transport of a substance across a membrane. Catalysis of the hydrolysis of an acid anhydride to directly drive the transport of a substance across a membrane. Catalysis of the reaction: peptide antigen(in) + ATP = peptide antigen(out) + ADP + phosphate. Enables the directed movement of peptides, compounds of two or more amino acids where the alpha carboxyl group of one is bound to the alpha amino group of another, into, out of, within or between cells. Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria. Catalysis of the reaction: ATP + H2O + oligopeptide(out) = ADP + phosphate + oligopeptide(in). Catalysis of the reaction: ATP + H2O = ADP + phosphate to directly drive the transport of a substance.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: peptide-transporting ATPase activity
Acc: GO:0015440
Aspect: Molecular Function
Desc: Catalysis of the reaction: ATP + H2O + peptide(in) = ADP + phosphate + peptide(out). Peptides exported include alpha-hemolysin, cyclolysin, colicin V and siderophores from Gram-negative bacteria, and bacteriocin, subtilin, competence factor and pediocin from Gram-positive bacteria.
Synonyms:
  • peptide ABC transporter
  • ATP phosphohydrolase (peptide-exporting)
Proteins in PDR annotated with:
   This term: 17 [Search]
   Term or descendants: 65 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0015440 - peptide-transporting ATPase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle