| Protein: | hop-PA |
| Organism: | Drosophila melanogaster |
| Length: | 1177 amino acids |
| Reference: | Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for hop-PA.
| Description | E-value | Query Range |
Subject Range |
|
|
872.0 | [0..1] | [1177..1] |
|
Region A: Residues: [1-284] |
1 11 21 31 41 51
| | | | | |
1 MALANGGEDR MDDSSSGRTS LADSASLTNS SLRSGTSSQS IHTNDGTIRV FNFTTGEFER 60
61 FHPNMLCEEI CNTMCRQLGI APIAQLLYGI REHSTSRRPS PLVRLDLTWC LPGERLNCQL 120
121 VYCFRMRFRV PELDSQLELI DGRSHKFLYR QMRYDMRTEQ IPEIRYPEHK DKSTGLAVMD 180
181 MLIDDQEQSE DQQAMRSIEK LYKLYLPPSL WRAHSFFVGS KIREVFRSLK ANSLSVERLK 240
241 WHYVHQVSHL APTYMTEQFT CTVQYLPNEE VARGSGPIGT SLAH
|
| Detection Method: |  |
| Confidence: | 4.44 |
| Match: | 2al6A |
| Description: | FERM domain of Focal Adhesion Kinase |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| protein binding | 2.78014377544701 | bayes_pls_golite062009 |
| binding | 2.70872150536621 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.35453941832029 | bayes_pls_golite062009 |
| transcription regulator activity | 2.23822335492051 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 2.06339025620966 | bayes_pls_golite062009 |
| DNA binding | 1.8833926783115 | bayes_pls_golite062009 |
| nucleic acid binding | 1.71711303358304 | bayes_pls_golite062009 |
| phosphotransferase activity, alcohol group as acceptor | 1.65143775864899 | bayes_pls_golite062009 |
| kinase activity | 1.63779463482357 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 1.53011388333584 | bayes_pls_golite062009 |
| protein kinase activity | 1.42846875539579 | bayes_pls_golite062009 |
| transferase activity | 1.27638139677762 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 1.18258299713791 | bayes_pls_golite062009 |
| actin binding | 1.12812097171372 | bayes_pls_golite062009 |
| signal transducer activity | 1.07208466109379 | bayes_pls_golite062009 |
| molecular transducer activity | 1.07208466109379 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 0.67884592236589 | bayes_pls_golite062009 |
| tubulin binding | 0.296026215424798 | bayes_pls_golite062009 |
| GTPase regulator activity | 0.172760623576326 | bayes_pls_golite062009 |
| nucleoside-triphosphatase regulator activity | 0.156922202244152 | bayes_pls_golite062009 |
| enzyme binding | 0.147520546067615 | bayes_pls_golite062009 |
| small conjugating protein ligase activity | 0.0883890683408073 | bayes_pls_golite062009 |
| structure-specific DNA binding | 0.0623044995795676 | bayes_pls_golite062009 |
| enzyme regulator activity | 0.0437862640556833 | bayes_pls_golite062009 |
| receptor binding | 0.00986014111393829 | bayes_pls_golite062009 |
|
Region A: Residues: [285-866] |
1 11 21 31 41 51
| | | | | |
1 STSTLASSGS TNTLSTLTTN TNSVALGGSG KKAKRRSTSG GIDVYVRVFP HDSLEPGLKV 60
61 ARVTSEATLK WILVGAVEGI FMISKINDTS VRLEIVGLPK GYEMQFQTEK EMKSFISYLG 120
121 IYIRLSSKWM QDLCHSYRTP SLEELSSLHC HGPIGGAYSL MKLHENGDKC GSYIVRECDR 180
181 EYNIYYIDIN TKIMAKKTDQ ERCKTETFRI VRKDSQWKLS YNNGEHVLNS LHEVAHIIQA 240
241 DSPDRYRIPA SKYDKPPLLL LLLPKNLKAK KTDLQLSEAE LQRRNPQIFN PRTDLQWYPD 300
301 SISLSDDGMM FTMRGDWIQQ SPVKDVSVTM KMLKSDGNFM EFFRLAQTWS LIQSPQFLKL 360
361 YGLTLADPYT MVMEYSRYGP LNKFLHSMPN VTLHCLLDLM HGLVRGMHYL EDNKIIHNYI 420
421 RCSNLYVTKY DPNSYVLDAK ISDPGYPRPY RESDSPWIPV KYYRNLQAAK TDQFAQLWAF 480
481 ATTIYEIFSR CKEDLSTLRQ EQLLRQKNLD GNILKMLDQD ICPAPIFETI MDGWSDDETK 540
541 RFSHHDIFSR LNTIKAEILP NYMPPPEIAT NGTGDETVID RS
|
| Detection Method: | |
| Confidence: | 117.0 |
| Match: | 2h8hA |
| Description: | No description for 2h8hA was found. |
| Term | Confidence | Notes |
| phosphotransferase activity, alcohol group as acceptor | 5.49988294224815 | bayes_pls_golite062009 |
| protein kinase activity | 5.4586557943719 | bayes_pls_golite062009 |
| kinase activity | 5.3287080791198 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 4.96052051118534 | bayes_pls_golite062009 |
| protein serine/threonine kinase activity | 4.46381887831481 | bayes_pls_golite062009 |
| transferase activity | 3.97138602499442 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase binding | 3.43994026029707 | bayes_pls_golite062009 |
| transmembrane receptor protein tyrosine kinase activity | 3.41480681854114 | bayes_pls_golite062009 |
| transmembrane receptor protein kinase activity | 3.40140621607334 | bayes_pls_golite062009 |
| insulin receptor activity | 3.20786175773448 | bayes_pls_golite062009 |
| PTB domain binding | 2.97926451113784 | bayes_pls_golite062009 |
| epidermal growth factor receptor binding | 2.9751846707539 | bayes_pls_golite062009 |
| protein tyrosine kinase activity | 2.8153155526437 | bayes_pls_golite062009 |
| binding | 2.74863538127007 | bayes_pls_golite062009 |
| SH2 domain binding | 2.69208419195971 | bayes_pls_golite062009 |
| transmembrane receptor activity | 2.59526003830791 | bayes_pls_golite062009 |
| molecular transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| signal transducer activity | 2.40586892801446 | bayes_pls_golite062009 |
| receptor activity | 2.39311927684508 | bayes_pls_golite062009 |
| protein binding | 2.276111749106 | bayes_pls_golite062009 |
| insulin-like growth factor receptor binding | 2.18795259566024 | bayes_pls_golite062009 |
| phosphatase activity | 2.10545147905564 | bayes_pls_golite062009 |
| receptor signaling protein activity | 2.10379226653669 | bayes_pls_golite062009 |
| phosphoric ester hydrolase activity | 2.06076411916645 | bayes_pls_golite062009 |
| ATP binding | 1.97600611746091 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.93596671856664 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.90928021591891 | bayes_pls_golite062009 |
| receptor signaling protein serine/threonine kinase activity | 1.81249386965144 | bayes_pls_golite062009 |
| molecular adaptor activity | 1.81145713371725 | bayes_pls_golite062009 |
| non-membrane spanning protein tyrosine kinase activity | 1.66669268613198 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.65732943334212 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.65726906484847 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.63763394711025 | bayes_pls_golite062009 |
| vinculin binding | 1.63216315345235 | bayes_pls_golite062009 |
| nucleotide binding | 1.63195828048121 | bayes_pls_golite062009 |
| insulin receptor substrate binding | 1.62657794525303 | bayes_pls_golite062009 |
| SH3/SH2 adaptor activity | 1.59474164216385 | bayes_pls_golite062009 |
| hydrolase activity, acting on ester bonds | 1.57005671465985 | bayes_pls_golite062009 |
| transcription regulator activity | 1.56748951434625 | bayes_pls_golite062009 |
| growth hormone receptor binding | 1.56531632362906 | bayes_pls_golite062009 |
| growth factor binding | 1.53863828216563 | bayes_pls_golite062009 |
| MAP kinase kinase activity | 1.42275431028856 | bayes_pls_golite062009 |
| DNA binding | 1.35333135345112 | bayes_pls_golite062009 |
| kinase binding | 1.26086833316556 | bayes_pls_golite062009 |
| insulin binding | 1.23861703046323 | bayes_pls_golite062009 |
| catalytic activity | 1.21655087018101 | bayes_pls_golite062009 |
| nucleic acid binding | 1.16049201286103 | bayes_pls_golite062009 |
| transporter activity | 1.11833481501707 | bayes_pls_golite062009 |
| transcription factor activity | 1.10928254946881 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity | 1.10045286406485 | bayes_pls_golite062009 |
| transmembrane receptor protein serine/threonine kinase activity | 1.10045286406485 | bayes_pls_golite062009 |
| phosphoprotein phosphatase activity | 1.07927533779326 | bayes_pls_golite062009 |
| protein kinase binding | 1.06030596516506 | bayes_pls_golite062009 |
| transmembrane transporter activity | 0.97575992765505 | bayes_pls_golite062009 |
| cyclin-dependent protein kinase activity | 0.959360414036299 | bayes_pls_golite062009 |
| platelet-derived growth factor receptor binding | 0.878815317889563 | bayes_pls_golite062009 |
| insulin-like growth factor II binding | 0.856861384729301 | bayes_pls_golite062009 |
| protein binding, bridging | 0.83823250804321 | bayes_pls_golite062009 |
| MAP kinase activity | 0.81943579965027 | bayes_pls_golite062009 |
| fibroblast growth factor receptor activity | 0.75189004129952 | bayes_pls_golite062009 |
| substrate-specific transporter activity | 0.705905455086486 | bayes_pls_golite062009 |
| hormone receptor binding | 0.705067960165986 | bayes_pls_golite062009 |
| transcription activator activity | 0.645254722299306 | bayes_pls_golite062009 |
| Janus kinase activity | 0.580310109637219 | bayes_pls_golite062009 |
| JUN kinase kinase kinase kinase activity | 0.546647574638943 | bayes_pls_golite062009 |
| activin binding | 0.510364757301021 | bayes_pls_golite062009 |
| steroid hormone receptor binding | 0.505233004492768 | bayes_pls_golite062009 |
| protein serine/threonine/tyrosine kinase activity | 0.48345772948903 | bayes_pls_golite062009 |
| enzyme binding | 0.46284745266176 | bayes_pls_golite062009 |
| substrate-specific transmembrane transporter activity | 0.450699332958421 | bayes_pls_golite062009 |
| protein kinase C activity | 0.41587987561486 | bayes_pls_golite062009 |
| magnesium ion binding | 0.393328812780268 | bayes_pls_golite062009 |
| protein tyrosine phosphatase activity | 0.384048681536292 | bayes_pls_golite062009 |
| 3-phosphoinositide-dependent protein kinase binding | 0.372842462336059 | bayes_pls_golite062009 |
| MAP kinase kinase kinase activity | 0.37115026509016 | bayes_pls_golite062009 |
| phosphotyrosine binding | 0.311079584914389 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.284465446035567 | bayes_pls_golite062009 |
| phosphoinositide 3-kinase regulator activity | 0.272902474317891 | bayes_pls_golite062009 |
| insulin receptor binding | 0.266450215230107 | bayes_pls_golite062009 |
| nuclear hormone receptor binding | 0.240883589532225 | bayes_pls_golite062009 |
| protein complex binding | 0.239339759110451 | bayes_pls_golite062009 |
| cell adhesion molecule binding | 0.150740450460731 | bayes_pls_golite062009 |
| ion transmembrane transporter activity | 0.148194101970458 | bayes_pls_golite062009 |
| actin binding | 0.144822861207099 | bayes_pls_golite062009 |
| peptide binding | 0.118578378753757 | bayes_pls_golite062009 |
| transforming growth factor beta receptor activity, type I | 0.0506751594607393 | bayes_pls_golite062009 |
| cation binding | 0.046173055856133 | bayes_pls_golite062009 |
| metal ion binding | 0.046173055856133 | bayes_pls_golite062009 |
| ion binding | 0.0389662058697694 | bayes_pls_golite062009 |
| nitric-oxide synthase regulator activity | 0.00407218246327123 | bayes_pls_golite062009 |
|
Region A: Residues: [867-1177] |
1 11 21 31 41 51
| | | | | |
1 DIPFLPFPRS NMLMVIPLTS ECRVIYNMEN MIGRGHYGTV YKGHLEFNDK DQPREQVAIK 60
61 MLNTMQVSTD FHREIGIMRT LSHPNIVKFK YWAEKSHCII MEYLQSGSFD IYLRFTAPNL 120
121 NNPRLVSFAL DIANGMKYLS DMGLIHRDLA ARNILVDHNG DGDCVKISDF GLAQFANSDG 180
181 YYYAKSKRDI PIRWYSPEAI STCRFSSYSD VWSYGVTLFE MFSRGEEPNL VPIQTSQEDF 240
241 LNRLQSGERL NRPASCPDFI YDLMQLCWHA TPRSRPSFAT IVDIITREVA TKVTHPTDGH 300
301 QSPPNQPTDA E
|
| Detection Method: | |
| Confidence: | 74.69897 |
| Match: | 2qoqA |
| Description: | No description for 2qoqA was found. |
