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View Structure Prediction Details

Protein: FBpp0302531
Organism: Drosophila melanogaster
Length: 547 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for FBpp0302531.

Description E-value Query
Range
Subject
Range
FBpp0302532 - type=protein; loc=3R:complement(14079276..14080038,14080097..14080958,14081039..14081102); ID=FBpp03...
422.0 [0..1] [547..1]

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Predicted Domain #1
Region A:
Residues: [1-75]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFMNPVDMV DEDAADLQFP KVEPLGPQVK RFIHAHQNEH TRNSMVLYNP HTLHRYLEEM  60
   61 EEKTRDQNSS VPSAT

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 7.69897
Match: 1eg3A
Description: Dystrophin
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
transferase activity, transferring phosphorus-containing groups 3.8744900429978 bayes_pls_golite062009
acyltransferase activity 3.35050943544976 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.31569325490599 bayes_pls_golite062009
transferase activity 3.23942674812578 bayes_pls_golite062009
binding 3.17556402087346 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.14878774301126 bayes_pls_golite062009
transcription regulator activity 2.23156041569913 bayes_pls_golite062009
nucleic acid binding 1.83723964306928 bayes_pls_golite062009
DNA binding 1.73924929536227 bayes_pls_golite062009
cytoskeletal protein binding 1.5869787076114 bayes_pls_golite062009
cation binding 1.19957754885754 bayes_pls_golite062009
metal ion binding 1.19957754885754 bayes_pls_golite062009
ion binding 1.19209803121473 bayes_pls_golite062009
protein binding 1.16246005294206 bayes_pls_golite062009
structural molecule activity 0.800850121197479 bayes_pls_golite062009
actin binding 0.637627956875516 bayes_pls_golite062009
motor activity 0.35554808768187 bayes_pls_golite062009
structural constituent of muscle 0.17143283003031 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [76-126]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 KDANRCATCR CSLTEPYIKC SECLDTLLCL QCFSRGKEAF SHRNNHAYII V

[Run NCBI BLAST on this sequence.]

Detection Method: FFAS03
Confidence: 2.28
Match: 2fc7A
Description: No description for 2fc7A was found.

Predicted functions:

Term Confidence Notes
general RNA polymerase II transcription factor activity 5.89167912663142 bayes_pls_golite062009
binding 2.70912934275371 bayes_pls_golite062009
transcription regulator activity 2.69310847474187 bayes_pls_golite062009
nucleic acid binding 2.31493818053907 bayes_pls_golite062009
small conjugating protein ligase activity 2.19099740571398 bayes_pls_golite062009
ubiquitin-protein ligase activity 2.07850206021921 bayes_pls_golite062009
DNA binding 2.0126776192216 bayes_pls_golite062009
protein binding 1.48593945455888 bayes_pls_golite062009
transcription factor activity 1.23220438818624 bayes_pls_golite062009
acid-amino acid ligase activity 1.21656984446301 bayes_pls_golite062009
transcription factor binding 0.987482369490121 bayes_pls_golite062009
RNA polymerase II transcription factor activity 0.876703944945945 bayes_pls_golite062009
ligase activity 0.497586458390942 bayes_pls_golite062009
transcription repressor activity 0.283643164965801 bayes_pls_golite062009
transcription coactivator activity 0.190105232754922 bayes_pls_golite062009
catalytic activity 0.168711389690753 bayes_pls_golite062009
transcription cofactor activity 0.137379573046724 bayes_pls_golite062009
transcription activator activity 0.111490592727037 bayes_pls_golite062009

Predicted Domain #3
Region A:
Residues: [127-211]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 RDNIQVFADE PHWTARDERI LLKTLRTHGY GNWEAVSQAL DQRHEPAEVR RHYHDCYFGG  60
   61 IFERLLNLKH ARDSYVPERM PYVFK

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #4
Region A:
Residues: [212-432]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MRSLDPPRHD DIASMQFRLS AGYRCARGDF DTPYDTSAES LLSIMVDHRG RDDDNEASES  60
   61 EFEREVTEEL QLGLVRAYNN RLRERQRRYK IMRQHGLIMP NRTVSWISKY VHAFGSDASC 120
  121 MRFLGFMQIC PDPIKFDMLL ESLRYYRELH SQLHKLYDLR EHGVRTLSGA KLYARLSKER 180
  181 QQAQRDYSRL KQTDAFDWQQ LVQHYESNRS GDPGPLAINS K

[Run NCBI BLAST on this sequence.]

Detection Method: MSA

Shown below is our most confident prediction for this domain.
Click here to view all matches.

Found no confident structure predictions for this domain.

Predicted Domain #5
Region A:
Residues: [433-547]
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 LYVMNTRRKA SPIEIGGGKH FTHCLTPTEY NFSLIPDLPG YSKLDDGERK LCSVARLVPQ  60
   61 SYLDYKNQLV TEQAKLGYLR LADARRLIKI DVNKTRQIYD FLLEHGHISR PPSYG

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 27.39794
Match: 2aqeA
Description: Structural and functional analysis of ada2 alpha swirm domain
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
lysine N-acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
histone acetyltransferase activity 5.80609397811031 bayes_pls_golite062009
general RNA polymerase II transcription factor activity 5.49431089902672 bayes_pls_golite062009
transcription regulator activity 5.13863038737912 bayes_pls_golite062009
DNA binding 4.66369707598026 bayes_pls_golite062009
N-acyltransferase activity 4.57418118498868 bayes_pls_golite062009
nucleic acid binding 4.51452285155271 bayes_pls_golite062009
N-acetyltransferase activity 4.37954729923498 bayes_pls_golite062009
transferase activity, transferring phosphorus-containing groups 4.09369451338399 bayes_pls_golite062009
transcription factor activity 4.06706589695599 bayes_pls_golite062009
RNA polymerase activity 3.9883025551666 bayes_pls_golite062009
DNA-directed RNA polymerase activity 3.9883025551666 bayes_pls_golite062009
acetyltransferase activity 3.80908511328212 bayes_pls_golite062009
acyltransferase activity 3.35206890637362 bayes_pls_golite062009
transferase activity, transferring acyl groups other than amino-acyl groups 3.30532537006075 bayes_pls_golite062009
RNA polymerase II transcription factor activity 3.16896789933192 bayes_pls_golite062009
transferase activity 3.10582783156108 bayes_pls_golite062009
transferase activity, transferring acyl groups 3.08442186629685 bayes_pls_golite062009
binding 3.02779747447702 bayes_pls_golite062009
nucleotidyltransferase activity 2.86344939956632 bayes_pls_golite062009
sequence-specific DNA binding 2.41271657675151 bayes_pls_golite062009
transcription repressor activity 1.91962622287073 bayes_pls_golite062009
transcription activator activity 1.77700860354597 bayes_pls_golite062009
specific RNA polymerase II transcription factor activity 1.73068440195944 bayes_pls_golite062009
chromatin binding 1.68956710349366 bayes_pls_golite062009
transcription factor binding 1.40653841901929 bayes_pls_golite062009
protein deacetylase activity 1.23680480131205 bayes_pls_golite062009
histone deacetylase activity 1.18932416576802 bayes_pls_golite062009
transcription cofactor activity 0.84983974758882 bayes_pls_golite062009
protein binding 0.830419844171551 bayes_pls_golite062009
DNA-dependent ATPase activity 0.666799964992178 bayes_pls_golite062009
histone binding 0.557787598121402 bayes_pls_golite062009
deacetylase activity 0.530687254192222 bayes_pls_golite062009
telomeric DNA binding 0.284650049512347 bayes_pls_golite062009
transcription coactivator activity 0.2679415219517 bayes_pls_golite062009
transcription corepressor activity 0.25931464844298 bayes_pls_golite062009
cytoskeletal protein binding 0.236060274498333 bayes_pls_golite062009
DNA helicase activity 0.187022204923867 bayes_pls_golite062009
structure-specific DNA binding 0.105174598157041 bayes_pls_golite062009

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle