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Protein Overview: FBpp0302532

General Information:
Name(s) found: FBpp0302532 [FlyBase]
Description(s) found:
Found 21 descriptions.
SHOW ALL
  • type=protein; loc=3R:complement(14079276..14080038,14080097..14080958,14081039..14081102); ID=FBpp0302532; name=Ada2a-PB; parent=FBgn0263738,FBtr0310381; dbxref=FlyBase:FBpp0302532,FlyBase_Annotation_IDs:CG43663-PB,REFSEQ:NP_001014636,GB_protein:AAS65168; MD5=a2280e3bcebd012bba231f1c0a556392; length=562; release=r5.56; species=Dmel; [FlyBase]
    • Organism: Drosophila melanogaster
    Length: 562 amino acids

    Gene Ontology:
    Cellular Component: nucleus [IDA]
    polytene chromosome [IDA]
    DNA-directed RNA polymerase II, holoenzyme [ISS]
    Ada2/Gcn5/Ada3 transcription activator complex [NAS]
    H4/H2A histone acetyltransferase complex [IDA]
    DNA-directed RNA polymerase II, core complex [IDA][ISS]
    histone acetyltransferase complex [IDA]
    Biological Process: mRNA transcription from RNA polymerase II promoter [IDA]
    cell proliferation [IDA]
    histone H3 acetylation [IDA]
    transcription [IEA]
    regulation of histone acetylation [IDA]
    transcription from RNA polymerase II promoter [IDA][ISS]
    Molecular Function: nucleotide binding [IEA]
    histone acetyltransferase activity [NAS]
    DNA binding [IEA]
    zinc ion binding [IEA]
    DNA-directed RNA polymerase activity [IDA][ISS]
    protein binding [IPI]
    transcription regulator activity [ISS]


    Sequence:
    Sequence:
    [PDR BLAST]
    [ProtParam] 
          1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MSFMNPVDMV DEDAADLQFP KVALLHIFTT LNCLFAVEPL GPQVKRFIHA HQNEHTRNSM  60
   61 VLYNPHTLHR YLEEMEEKTR DQNSSVPSAT KDANRCATCR CSLTEPYIKC SECLDTLLCL 120
  121 QCFSRGKEAF SHRNNHAYII VRDNIQVFAD EPHWTARDER ILLKTLRTHG YGNWEAVSQA 180
  181 LDQRHEPAEV RRHYHDCYFG GIFERLLNLK HARDSYVPER MPYVFKMRSL DPPRHDDIAS 240
  241 MQFRLSAGYR CARGDFDTPY DTSAESLLSI MVDHRGRDDD NEASESEFER EVTEELQLGL 300
  301 VRAYNNRLRE RQRRYKIMRQ HGLIMPNRTV SWISKYVHAF GSDASCMRFL GFMQICPDPI 360
  361 KFDMLLESLR YYRELHSQLH KLYDLREHGV RTLSGAKLYA RLSKERQQAQ RDYSRLKQTD 420
  421 AFDWQQLVQH YESNRSGDPG PLAINSKLYV MNTRRKASPI EIGGGKHFTH CLTPTEYNFS 480
  481 LIPDLPGYSK LDDGERKLCS VARLVPQSYL DYKNQLVTEQ AKLGYLRLAD ARRLIKIDVN 540
  541 KTRQIYDFLL EHGHISRPPS YG

    Protein Complex Data

    No complex found for this protein.

    Mass Spectrometry Data

    No mass spectrometry results found for this protein.

    Yeast Two-Hybrid Data

    The following interactions contain this protein:

    NOT SHOWING SINGLE HITS. [ Show Single Hits ]

    [View our yeast two-hybrid interpretation guidelines.]

    No yeast two-hybrid interactions found for this protein.

    Microscopy / Localization Data

    New Feature: Upload Your Own Microscopy Data

    No microscopy data found in the PDR for this protein.

    Protein Structure Data


    [What does the above image mean?]
    [View Top Sequence Alignments] [Show Ginzu Version Information]

    Domains predicted:

    #   Region(s) Method Confidence Match Description
    1 View Details [1..89] PSI-BLAST 9.30103 Dystrophin
    2 View Details [90..148] PSI-BLAST 7.30103 No description for 2e5rA was found.
    3 View Details [149..324] FFAS03 2.84 CHICKEN B-MYB DNA BINDING DOMAIN, REPEAT 2 AND REPEAT3, NMR, 32 STRUCTURES
    4 View Details [325..442] MSA 1.166992 View MSA. No confident structure predictions are available.
    5 View Details [443..562] PSI-BLAST 26.0 Solution structure of SWIRM domain of mouse transcriptional adaptor 2-like

    Functions predicted (by domain):

    # Gene Ontology predictions
    1 No functions predicted.
    2 No functions predicted.
    3
    Term Confidence Notes
  • lysine N-acetyltransferase activity
    		•  5.78270240334849 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.78270240334849 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  5.44968936347013 bayes_pls_golite062009
  • transcription regulator activity
    		•  4.86538715425734 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.53404381270892 bayes_pls_golite062009
  • DNA binding
    		•  4.40186699787632 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.38345537045529 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.28652307290136 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.10362956884303 bayes_pls_golite062009
  • RNA polymerase activity
    		•  3.99233443365099 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  3.99233443365099 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.81897719505269 bayes_pls_golite062009
  • transcription factor activity
    		•  3.78935192723648 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.35931919126926 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.31384699789032 bayes_pls_golite062009
  • transferase activity
    		•  3.16343875008119 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.09869056563841 bayes_pls_golite062009
  • binding
    		•  2.92574888336072 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  2.91588376840709 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  2.87182202022318 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.15328641013602 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.69615348178304 bayes_pls_golite062009
  • transcription activator activity
    		•  1.5973137667873 bayes_pls_golite062009
  • chromatin binding
    		•  1.46954724788757 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.44773725829085 bayes_pls_golite062009
  • transcription factor binding
    		•  1.24678737091956 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.23476914879396 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.18710646783152 bayes_pls_golite062009
  • protein binding
    		•  0.795494287543952 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.691780246385357 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.658518317984762 bayes_pls_golite062009
  • deacetylase activity
    		•  0.534082291544628 bayes_pls_golite062009
  • histone binding
    		•  0.489784140732052 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.244471307852075 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.233668696331578 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.201150053959035 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.192832786095412 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.0880065228906077 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.0723215858239072 bayes_pls_golite062009
    4 No functions predicted.
    5
    Term Confidence Notes
  • lysine N-acetyltransferase activity
    		•  5.80609397811031 bayes_pls_golite062009
  • histone acetyltransferase activity
    		•  5.80609397811031 bayes_pls_golite062009
  • general RNA polymerase II transcription factor activity
    		•  5.49431089902672 bayes_pls_golite062009
  • transcription regulator activity
    		•  5.13863038737912 bayes_pls_golite062009
  • DNA binding
    		•  4.66369707598026 bayes_pls_golite062009
  • N-acyltransferase activity
    		•  4.57418118498868 bayes_pls_golite062009
  • nucleic acid binding
    		•  4.51452285155271 bayes_pls_golite062009
  • N-acetyltransferase activity
    		•  4.37954729923498 bayes_pls_golite062009
  • transferase activity, transferring phosphorus-containing groups
    		•  4.09369451338399 bayes_pls_golite062009
  • transcription factor activity
    		•  4.06706589695599 bayes_pls_golite062009
  • RNA polymerase activity
    		•  3.9883025551666 bayes_pls_golite062009
  • DNA-directed RNA polymerase activity
    		•  3.9883025551666 bayes_pls_golite062009
  • acetyltransferase activity
    		•  3.80908511328212 bayes_pls_golite062009
  • acyltransferase activity
    		•  3.35206890637362 bayes_pls_golite062009
  • transferase activity, transferring acyl groups other than amino-acyl groups
    		•  3.30532537006075 bayes_pls_golite062009
  • RNA polymerase II transcription factor activity
    		•  3.16896789933192 bayes_pls_golite062009
  • transferase activity
    		•  3.10582783156108 bayes_pls_golite062009
  • transferase activity, transferring acyl groups
    		•  3.08442186629685 bayes_pls_golite062009
  • binding
    		•  3.02779747447702 bayes_pls_golite062009
  • nucleotidyltransferase activity
    		•  2.86344939956632 bayes_pls_golite062009
  • sequence-specific DNA binding
    		•  2.41271657675151 bayes_pls_golite062009
  • transcription repressor activity
    		•  1.91962622287073 bayes_pls_golite062009
  • transcription activator activity
    		•  1.77700860354597 bayes_pls_golite062009
  • specific RNA polymerase II transcription factor activity
    		•  1.73068440195944 bayes_pls_golite062009
  • chromatin binding
    		•  1.68956710349366 bayes_pls_golite062009
  • transcription factor binding
    		•  1.40653841901929 bayes_pls_golite062009
  • protein deacetylase activity
    		•  1.23680480131205 bayes_pls_golite062009
  • histone deacetylase activity
    		•  1.18932416576802 bayes_pls_golite062009
  • transcription cofactor activity
    		•  0.84983974758882 bayes_pls_golite062009
  • protein binding
    		•  0.830419844171551 bayes_pls_golite062009
  • DNA-dependent ATPase activity
    		•  0.666799964992178 bayes_pls_golite062009
  • histone binding
    		•  0.557787598121402 bayes_pls_golite062009
  • deacetylase activity
    		•  0.530687254192222 bayes_pls_golite062009
  • telomeric DNA binding
    		•  0.284650049512347 bayes_pls_golite062009
  • transcription coactivator activity
    		•  0.2679415219517 bayes_pls_golite062009
  • transcription corepressor activity
    		•  0.25931464844298 bayes_pls_golite062009
  • cytoskeletal protein binding
    		•  0.236060274498333 bayes_pls_golite062009
  • DNA helicase activity
    		•  0.187022204923867 bayes_pls_golite062009
  • structure-specific DNA binding
    		•  0.105174598157041 bayes_pls_golite062009


    Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16


    Philius Transmembrane Prediction:

    Protein predicted to be: GLOBULAR (No transmembrane regions or signal peptide)
    Confidence of classification: 0.95

    Source: Reynolds et al. (2008)

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle