| Protein: | MCM7 |
| Organism: | Saccharomyces cerevisiae |
| Length: | 845 amino acids |
| Reference: | Malmström L, et al. (2007) Superfamily assignments for the yeast proteome through integration of structure prediction with the gene ontology. PLoS Biol 5(4): e76. doi:10.1371/journal.pbio.0050076 |
Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for MCM7.
| Description | E-value | Query Range |
Subject Range |
|
|
0.0 | [1..845] | [1..845] |
|
|
0.0 | [33..804] | [3..719] |
|
|
0.0 | [33..804] | [3..719] |
|
|
0.0 | [34..804] | [3..720] |
|
|
0.0 | [34..804] | [3..720] |
|
|
0.0 | [4..805] | [2..753] |
|
|
0.0 | [36..804] | [1..716] |
|
Region A: Residues: [1-206] |
1 11 21 31 41 51
| | | | | |
1 MSAALPSIQL PVDYNNLFNE ITDFLVTFKQ DTLSSDATRN ENEDENLDAE NIEQHLLEKG 60
61 PKYMAMLQKV ANRELNSVII DLDDILQYQN EKFLQGTQAD DLVSAIQQNA NHFTELFCRA 120
121 IDNNMPLPTK EIDYKDDVLD VILNQRRLRN ERMLSDRTNE IRSENLMDTT MDPPSSMNDA 180
181 LREVVEDETE LFPPNLTRRY FLYFKP
|
| Detection Method: |  |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
|
Region A: Residues: [207-417] |
1 11 21 31 41 51
| | | | | |
1 LSQNCARRYR KKAISSKPLS VRQIKGDFLG QLITVRGIIT RVSDVKPAVE VIAYTCDQCG 60
61 YEVFQEVNSR TFTPLSECTS EECSQNQTKG QLFMSTRASK FSAFQECKIQ ELSQQVPVGH 120
121 IPRSLNIHVN GTLVRSLSPG DIVDVTGIFL PAPYTGFKAL KAGLLTETYL EAQFVRQHKK 180
181 KFASFSLTSD VEERVMELIT SGDVYNRLAK S
|
| Detection Method: | |
| Confidence: | 8.79588 |
| Match: | PF00493 |
| Description: | MCM2/3/5 family |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
Found no structure predictions for this domain.
| Term | Confidence | Notes |
| nucleic acid binding | 4.29626483284963 | bayes_pls_golite062009 |
| DNA binding | 3.71771169141041 | bayes_pls_golite062009 |
| structure-specific DNA binding | 3.48139490984491 | bayes_pls_golite062009 |
| single-stranded DNA binding | 3.43027351695641 | bayes_pls_golite062009 |
| binding | 2.83465364476231 | bayes_pls_golite062009 |
| telomerase inhibitor activity | 2.77979101622935 | bayes_pls_golite062009 |
| structural constituent of ribosome | 2.13063800565247 | bayes_pls_golite062009 |
| transcription regulator activity | 2.10110937001387 | bayes_pls_golite062009 |
| structural molecule activity | 1.9177190829469 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.84819558112187 | bayes_pls_golite062009 |
| telomeric DNA binding | 1.7847835613194 | bayes_pls_golite062009 |
| 3'-5'-exoribonuclease activity | 1.54401231841266 | bayes_pls_golite062009 |
| single-stranded telomeric DNA binding | 1.48033977789232 | bayes_pls_golite062009 |
| aminoacyl-tRNA ligase activity | 1.35850109411274 | bayes_pls_golite062009 |
| ligase activity, forming carbon-oxygen bonds | 1.35845277283398 | bayes_pls_golite062009 |
| ligase activity, forming aminoacyl-tRNA and related compounds | 1.35845277283398 | bayes_pls_golite062009 |
| transcription repressor activity | 1.30343463892105 | bayes_pls_golite062009 |
| DNA-directed RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| RNA polymerase activity | 1.19766815287926 | bayes_pls_golite062009 |
| ribonuclease activity | 1.19236946227657 | bayes_pls_golite062009 |
| transcription factor activity | 1.14242112812892 | bayes_pls_golite062009 |
| DNA helicase activity | 1.12203697857261 | bayes_pls_golite062009 |
| sequence-specific DNA binding | 0.85691075793641 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 0.638831894247026 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.583085644017496 | bayes_pls_golite062009 |
| nuclease activity | 0.57381531077345 | bayes_pls_golite062009 |
| ligase activity | 0.346041081217685 | bayes_pls_golite062009 |
| nucleotidyltransferase activity | 0.325774164899685 | bayes_pls_golite062009 |
| double-stranded DNA binding | 0.314881439089948 | bayes_pls_golite062009 |
| translation regulator activity | 0.31332179848255 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.311535572386606 | bayes_pls_golite062009 |
| exonuclease activity | 0.28313884527829 | bayes_pls_golite062009 |
| translation factor activity, nucleic acid binding | 0.263197317040851 | bayes_pls_golite062009 |
| translation initiation factor activity | 0.2080607201312 | bayes_pls_golite062009 |
| chromatin binding | 0.19409870825073 | bayes_pls_golite062009 |
| RNA binding | 0.18502033889261 | bayes_pls_golite062009 |
| protein binding | 0.152645195799531 | bayes_pls_golite062009 |
| aspartate-tRNA ligase activity | 0.151650064901878 | bayes_pls_golite062009 |
| exoribonuclease activity, producing 5'-phosphomonoesters | 0.125256208482441 | bayes_pls_golite062009 |
| exoribonuclease activity | 0.109774918833391 | bayes_pls_golite062009 |
| exonuclease activity, active with either ribo- or deoxyribonucleic acids and producing 5'-phosphomonoesters | 0.0954216620147701 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 0.0179535526984695 | bayes_pls_golite062009 |
| helicase activity | 0.0121541775159524 | bayes_pls_golite062009 |
|
Region A: Residues: [418-646] |
1 11 21 31 41 51
| | | | | |
1 IAPEIYGNLD VKKALLLLLV GGVDKRVGDG MKIRGDINVC LMGDPGVAKS QLLKAICKIS 60
61 PRGVYTTGKG SSGVGLTAAV MKDPVTDEMI LEGGALVLAD NGICCIDEFD KMDESDRTAI 120
121 HEVMEQQTIS ISKAVINTNP GARTSILAAA NPLYGRINPR LSPLDNINLP AALLSRFDIL 180
181 FLMLDIPSRD DDEKLAEHVT YVHMHNKQPD LDFTPVEPSK MREYIAYAK
|
| Detection Method: | |
| Confidence: | 46.522879 |
| Match: | 1g8pA_ |
| Description: | ATPase subunit of magnesium chelatase, BchI |
Matching Structure (courtesy of the PDB): |
|
| Term | Confidence | Notes |
| DNA clamp loader activity | 4.91429252297969 | bayes_pls_golite062009 |
| protein-DNA loading ATPase activity | 4.80695929076807 | bayes_pls_golite062009 |
| DNA-dependent ATPase activity | 2.72462789867829 | bayes_pls_golite062009 |
| general RNA polymerase II transcription factor activity | 2.66107861968804 | bayes_pls_golite062009 |
| binding | 2.64537357529343 | bayes_pls_golite062009 |
| nucleic acid binding | 2.51683451033161 | bayes_pls_golite062009 |
| DNA helicase activity | 2.2817164193758 | bayes_pls_golite062009 |
| pyrophosphatase activity | 2.13284212711072 | bayes_pls_golite062009 |
| DNA binding | 2.12258000781149 | bayes_pls_golite062009 |
| transcription regulator activity | 2.09345198747025 | bayes_pls_golite062009 |
| ATP-dependent DNA helicase activity | 1.88455339138556 | bayes_pls_golite062009 |
| helicase activity | 1.70242731830224 | bayes_pls_golite062009 |
| RNA helicase activity | 1.63960194106079 | bayes_pls_golite062009 |
| DNA replication origin binding | 1.62491387774159 | bayes_pls_golite062009 |
| ATP-dependent RNA helicase activity | 1.61735400124552 | bayes_pls_golite062009 |
| RNA-dependent ATPase activity | 1.60404584546501 | bayes_pls_golite062009 |
| ribonucleotide binding | 1.53142082854758 | bayes_pls_golite062009 |
| purine nucleotide binding | 1.52938239070386 | bayes_pls_golite062009 |
| purine ribonucleotide binding | 1.52887308780164 | bayes_pls_golite062009 |
| nucleotide binding | 1.52746968836881 | bayes_pls_golite062009 |
| microtubule motor activity | 1.35938517416356 | bayes_pls_golite062009 |
| ATP binding | 1.23942044024113 | bayes_pls_golite062009 |
| adenyl ribonucleotide binding | 1.21044170258803 | bayes_pls_golite062009 |
| structure-specific DNA binding | 1.20315703345493 | bayes_pls_golite062009 |
| adenyl nucleotide binding | 1.19481945569892 | bayes_pls_golite062009 |
| ATP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| purine NTP-dependent helicase activity | 1.19311444180077 | bayes_pls_golite062009 |
| double-stranded DNA binding | 1.05408274676326 | bayes_pls_golite062009 |
| catalytic activity | 1.00104173493322 | bayes_pls_golite062009 |
| DNA-directed DNA polymerase activity | 0.971476020912368 | bayes_pls_golite062009 |
| DNA polymerase activity | 0.928091843881235 | bayes_pls_golite062009 |
| transcription factor activity | 0.887108427603557 | bayes_pls_golite062009 |
| transcription repressor activity | 0.862685397469217 | bayes_pls_golite062009 |
| hydrogen ion transporting ATP synthase activity, rotational mechanism | 0.8469248456592 | bayes_pls_golite062009 |
| kinase activity | 0.641541011250583 | bayes_pls_golite062009 |
| motor activity | 0.61636596887462 | bayes_pls_golite062009 |
| transferase activity, transferring phosphorus-containing groups | 0.584453361662212 | bayes_pls_golite062009 |
| single-stranded DNA binding | 0.406600732518248 | bayes_pls_golite062009 |
| protein kinase activity | 0.351308564667977 | bayes_pls_golite062009 |
| RNA polymerase II transcription factor activity | 0.243902356228423 | bayes_pls_golite062009 |
| protein binding | 0.170837278876362 | bayes_pls_golite062009 |
| hydrogen ion transmembrane transporter activity | 0.156278588350022 | bayes_pls_golite062009 |
| nucleoside-triphosphatase activity | 0.147579541298736 | bayes_pls_golite062009 |
| mismatched DNA binding | 0.13366911641814 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides | 0.113504049290503 | bayes_pls_golite062009 |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | 0.111293884322157 | bayes_pls_golite062009 |
| structural constituent of ribosome | 0.089234257580272 | bayes_pls_golite062009 |
| 3'-5' DNA helicase activity | 0.0769112340058804 | bayes_pls_golite062009 |
| histone methyltransferase activity (H3-K9 specific) | 0.0642842984371965 | bayes_pls_golite062009 |
| cytoskeletal protein binding | 0.0272673919333979 | bayes_pls_golite062009 |
| monovalent inorganic cation transmembrane transporter activity | 0.0223627159838333 | bayes_pls_golite062009 |
|
Region A: Residues: [647-760] |
1 11 21 31 41 51
| | | | | |
1 TKRPVMSEAV NDYVVQAYIR LRQDSKREMD SKFSFGQATP RTLLGIIRLS QALAKLRLAD 60
61 MVDIDDVEEA LRLVRVSKES LYQETNKSKE DESPTTKIFT IIKKMLQETG KNTL
|
| Detection Method: | |
| Confidence: | 46.522879 |
| Match: | 1g8pA_ |
| Description: | ATPase subunit of magnesium chelatase, BchI |
| Matching Structure (courtesy of the PDB): |
|
|
Region A: Residues: [761-845] |
1 11 21 31 41 51
| | | | | |
1 SYENIVKTVR LRGFTMLQLS NCIQEYSYLN VWHLINEGNT LKFVDDGTMD TDQEDSLVST 60
61 PKLAPQTTAS ANVSAQDSDI DLQDA
|
| Detection Method: | |
Shown below are all of our structure predictions for this domain.
Click here to view only most confident match.
| MCM Score |
GO Score |
GO Term |
SCOP Match |
SCOP Description | ||
| View | Download | 0.466 | 0.223 | pre-replicative complex assembly | d.93.1 | SH2 domain |
| View | Download | 0.334 | 0.192 | pre-replicative complex assembly | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.425 | 0.075 | pre-replicative complex assembly | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.396 | 0.065 | pre-replicative complex assembly | d.58.3 | Protease propeptides/inhibitors |
| View | Download | 0.380 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.317 | N/A | N/A | d.68.6 | DNA-binding protein Sso10b (AlbA) |
| View | Download | 0.307 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.304 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.287 | N/A | N/A | c.15.1 | BRCT domain |
| View | Download | 0.279 | N/A | N/A | g.3.7 | Scorpion toxin-like |
| View | Download | 0.266 | N/A | N/A | a.77.1 | DEATH domain |
| View | Download | 0.265 | N/A | N/A | c.30.1 | PreATP-grasp domain |
| View | Download | 0.256 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.255 | N/A | N/A | g.3.7 | Scorpion toxin-like |
| View | Download | 0.250 | N/A | N/A | d.58.7 | RNA-binding domain, RBD |
| View | Download | 0.246 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.246 | N/A | N/A | a.35.1 | lambda repressor-like DNA-binding domains |
| View | Download | 0.237 | N/A | N/A | d.53.1 | Ribosomal protein S3 C-terminal domain |
| View | Download | 0.234 | N/A | N/A | c.51.1 | Anticodon-binding domain of Class II aaRS |
| View | Download | 0.233 | N/A | N/A | d.58.10 | Acylphosphatase-like |
| View | Download | 0.231 | N/A | N/A | d.93.1 | SH2 domain |
| View | Download | 0.229 | N/A | N/A | c.84.1 | Phosphoglucomutase, first 3 domains |
| View | Download | 0.207 | N/A | N/A | d.58.17 | Metal-binding domain |
| View | Download | 0.205 | N/A | N/A | d.53.1 | Ribosomal protein S3 C-terminal domain |
| View | Download | 0.204 | N/A | N/A | a.6.1 | Putative DNA-binding domain |
| View | Download | 0.203 | N/A | N/A | d.93.1 | SH2 domain |
