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View Structure Prediction Details

Protein: GMK2_ARATH
Organism: Arabidopsis thaliana
Length: 389 amino acids
Reference: Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16



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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for GMK2_ARATH.

Description E-value Query
Range		 Subject
Range
gi|79315417 - gi|79315417|ref|NP_001030877.1| AGK2 (GUANYLATE KINASE); guanylate kinase [Arabidopsis thaliana]
 376.0 [0..1] [389..1]

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Predicted Domain #1
Region A:
Residues: [1-112] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MGEAPAFFVD HLENGYTNGF GVKSEPKNRD TSVLIGDRSF VIGGNHEGNP LFLGVQIHDK  60
   61 VTNKWSSPSV LGTGPKPCKG YSAIVLPKGR ILVIKKGSAS DDSIWFLEVD TP

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 8.0
Match: 1t0hA
Description: Crystal structure of the Rattus norvegicus voltage gated calcium channel beta subunit isoform 2a
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
cytoskeletal protein binding 3.51280661609925 bayes_pls_golite062009
binding 3.06905798270146 bayes_pls_golite062009
actin binding 2.4886142982742 bayes_pls_golite062009
protein binding 2.08632303609243 bayes_pls_golite062009
signal transducer activity 1.6178155951679 bayes_pls_golite062009
molecular transducer activity 1.6178155951679 bayes_pls_golite062009
actin filament binding 1.36283509598507 bayes_pls_golite062009
transporter activity 1.30447542854757 bayes_pls_golite062009
transmembrane transporter activity 1.08558010881058 bayes_pls_golite062009
substrate-specific transporter activity 0.820987609295422 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 0.570864043201529 bayes_pls_golite062009
ion transmembrane transporter activity 0.277388904131159 bayes_pls_golite062009
structural constituent of muscle 0.00103496038381001 bayes_pls_golite062009

Predicted Domain #2
Region A:
Residues: [113-389] 
      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 FIREQKKLLG REVVAWSKGV RGNAEKPIVI SGPSGVGKGT LISMLMKEFP SMFGFSVSHT  60
   61 TRAPRCMEKN GVHYHFTDKT VMEKEIKDGK FLEFASVHGN LYGTSIESVE VVTDSGKRCI 120
  121 LDIDVQGARS VKASSLDAIF IFVCPPSMKE LEDRLRARGT ETEEQIQKRL RNADAEIKAG 180
  181 KSSGIFEHKL YNDNLEECYK TLKNLLGIND LAPVNGVEVE GINLPKEHTV TKMDDKILIQ 240
  241 ETGEGTKNKM IVLDLSSING GAPGRTRGIV LDTVKSS

[Run NCBI BLAST on this sequence.]

Detection Method: PSI-BLAST
Confidence: 60.0
Match: 1lvgA
Description: Guanylate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term Confidence Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism 4.94368959158184 bayes_pls_golite062009
GTPase activity 4.06265232661098 bayes_pls_golite062009
hydrogen ion transmembrane transporter activity 4.00431985024242 bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity 3.88411242531695 bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity 3.66392587433723 bayes_pls_golite062009
transporter activity 3.10463051760206 bayes_pls_golite062009
transmembrane transporter activity 2.95886887664984 bayes_pls_golite062009
nucleoside-triphosphatase activity 2.95079405147356 bayes_pls_golite062009
pyrophosphatase activity 2.87427509025394 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides 2.85499564954033 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides 2.85178667290149 bayes_pls_golite062009
binding 2.64537357529343 bayes_pls_golite062009
primary active transmembrane transporter activity 2.61775212528604 bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity 2.61467977505707 bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances 2.57552435627908 bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances 2.57107347424517 bayes_pls_golite062009
ATPase activity, coupled to movement of substances 2.57054427875021 bayes_pls_golite062009
active transmembrane transporter activity 2.50494515048649 bayes_pls_golite062009
ATPase activity, coupled 2.43862163407966 bayes_pls_golite062009
motor activity 2.40267948113603 bayes_pls_golite062009
ATPase activity 2.39535714892224 bayes_pls_golite062009
nucleotide kinase activity 2.24094813695083 bayes_pls_golite062009
glutamate receptor binding 2.18149167417819 bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor 1.96697952975573 bayes_pls_golite062009
substrate-specific transporter activity 1.91091452720653 bayes_pls_golite062009
microtubule motor activity 1.77441050776692 bayes_pls_golite062009
hydrolase activity 1.57549510726226 bayes_pls_golite062009
substrate-specific transmembrane transporter activity 1.56325751172863 bayes_pls_golite062009
cytoskeletal protein binding 1.50574672650697 bayes_pls_golite062009
nucleic acid binding 1.08697924060619 bayes_pls_golite062009
catalytic activity 1.00104173493322 bayes_pls_golite062009
guanylate kinase activity 0.98934362137863 bayes_pls_golite062009
ion transmembrane transporter activity 0.977237423302079 bayes_pls_golite062009
signal transducer activity 0.952448314982579 bayes_pls_golite062009
molecular transducer activity 0.952448314982579 bayes_pls_golite062009
purine nucleotide binding 0.929901285538132 bayes_pls_golite062009
nucleotide binding 0.922442819194247 bayes_pls_golite062009
purine ribonucleotide binding 0.920987930180051 bayes_pls_golite062009
ribonucleotide binding 0.920926158369519 bayes_pls_golite062009
peptide-transporting ATPase activity 0.911425383309011 bayes_pls_golite062009
actin binding 0.875514430441177 bayes_pls_golite062009
peptide transporter activity 0.73541731084591 bayes_pls_golite062009
DNA binding 0.702147676354075 bayes_pls_golite062009
cation transmembrane transporter activity 0.557919489256916 bayes_pls_golite062009
anion transmembrane-transporting ATPase activity 0.48775834126327 bayes_pls_golite062009
adenylate kinase activity 0.447752711852745 bayes_pls_golite062009
microfilament motor activity 0.415173945174069 bayes_pls_golite062009
ATP binding 0.41092997612902 bayes_pls_golite062009
adenyl ribonucleotide binding 0.385813421701492 bayes_pls_golite062009
adenyl nucleotide binding 0.377870145186619 bayes_pls_golite062009
transcription regulator activity 0.312171320541728 bayes_pls_golite062009
receptor activity 0.277332279568238 bayes_pls_golite062009
tubulin binding 0.264882086048416 bayes_pls_golite062009
inorganic anion transmembrane transporter activity 0.25714006331445 bayes_pls_golite062009
transmembrane receptor activity 0.243026482777117 bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism 0.20818362273204 bayes_pls_golite062009
protein binding 0.170837278876362 bayes_pls_golite062009
microtubule binding 0.156470772916507 bayes_pls_golite062009
inorganic cation transmembrane transporter activity 0.123304946374679 bayes_pls_golite062009
metal ion transmembrane transporter activity 0.0775601177068852 bayes_pls_golite062009
helicase activity 0.0775311459068899 bayes_pls_golite062009
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