YRC Public Data Repository - Protein Structure Prediction

Protein:	gi\|51858957
Organism:	Xenopus laevis
Length:	198 amino acids
Reference:	Drew K, et al. (2011) The proteome folding project: Proteome-scale prediction of structure and function. Genome Res. 2011 Sep 16

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Top Sequence Alignment Hits

Listed below are up to the top 10 sequence alignment matches, by species, for the PSI-BLAST search against the protein sequence for gi|51858957.

Description	E-value	Query Range	Subject Range
gi\|118786786, gi... - gi\|118786786\|ref\|XP_315658.2\| ENSANGP00000021663 [Anopheles gambiae str. PEST], gi\|116126488\|gb\|EAA1...	185.0	[0..2]	[194..411]
gi\|158971, gi\|422285 - pir\|\|S30327 multidrug resistance protein 1 - Entamoeba histolytica, gi\|158971\|gb\|AAA29112.1\| P-glyc...	184.0	[0..2]	[196..421]
gi\|56468541, gi\|... - gi\|67471688\|ref\|XP_651764.1\| P-glycoprotein-1 [Entamoeba histolytica HM-1:IMSS], gi\|56468541\|gb\|EAL4...	184.0	[0..2]	[196..421]
gi\|48825712 - ref\|ZP_00286952.1\| COG1132: ABC-type multidrug transport system, ATPase and permease components [Ent... gi\|68195849, gi\|... - gi\|69245319\|ref\|ZP_00603363.1\| ABC transporter, transmembrane region:ABC transporter [Enterococcus f...	181.0	[0..2]	[196..412]
gi\|66947665 - gi\|66947665\|emb\|CAI99869.1\| putative multidrug resistance protein 1 [Brachidontes pharaonis]	180.0	[0..2]	[191..498]
gi\|83365388, gi\|... - gi\|83372916\|ref\|ZP_00917695.1\| ATPas [Rhodobacter sphaeroides ATCC 17029], gi\|83365388\|gb\|EAP68875.1...	180.0	[0..2]	[196..687]
gi\|116269131, gi... - gi\|145588857\|ref\|YP_001155454.1\| ABC transporter related [Polynucleobacter necessarius subsp. asymbi...	178.0	[0..3]	[196..531]
gi\|71908875, gi\|... - gi\|71908875\|ref\|YP_286462.1\| ABC transporter, transmembrane region:ABC transporter related [Dechloro...	178.0	[0..2]	[196..531]

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Predicted Domain #1

Region A:
Residues: [1-198]

      1          11         21         31         41         51         
      |          |          |          |          |          |          
    1 MAGPRPVVLS GPSGAGKSTL LKKLFQEHSS IFGFSVSHTT RNPRPGEEDG KDYYFVTREM  60
   61 MQRDIAAGDF IEHAEFSGNL YGTSKEAVRA VQAMNRICVL DVDLQGVRSI KKTDLCPIYI 120
  121 FVQPPSLDVL EQRLRLRNTE TEESLAKRLA AARTDMESSK EPGLFDLVII NDDLDKAYAT 180
  181 LKQALSEEIK KAQGTGHA

[Run NCBI BLAST on this sequence.]

Detection Method:	PSI-BLAST
Confidence:	44.522879
Match:	1lvgA
Description:	Guanylate kinase
Matching Structure (courtesy of the PDB):

Predicted functions:

Term	Confidence	Notes
hydrogen ion transporting ATP synthase activity, rotational mechanism	4.94368959158184	bayes_pls_golite062009
GTPase activity	4.06265232661098	bayes_pls_golite062009
hydrogen ion transmembrane transporter activity	4.00431985024242	bayes_pls_golite062009
monovalent inorganic cation transmembrane transporter activity	3.88411242531695	bayes_pls_golite062009
nucleobase, nucleoside, nucleotide kinase activity	3.66392587433723	bayes_pls_golite062009
transporter activity	3.10463051760206	bayes_pls_golite062009
transmembrane transporter activity	2.95886887664984	bayes_pls_golite062009
nucleoside-triphosphatase activity	2.95079405147356	bayes_pls_golite062009
pyrophosphatase activity	2.87427509025394	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides	2.85499564954033	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	2.85178667290149	bayes_pls_golite062009
binding	2.64537357529343	bayes_pls_golite062009
primary active transmembrane transporter activity	2.61775212528604	bayes_pls_golite062009
P-P-bond-hydrolysis-driven transmembrane transporter activity	2.61467977505707	bayes_pls_golite062009
hydrolase activity, acting on acid anhydrides, catalyzing transmembrane movement of substances	2.57552435627908	bayes_pls_golite062009
ATPase activity, coupled to transmembrane movement of substances	2.57107347424517	bayes_pls_golite062009
ATPase activity, coupled to movement of substances	2.57054427875021	bayes_pls_golite062009
active transmembrane transporter activity	2.50494515048649	bayes_pls_golite062009
ATPase activity, coupled	2.43862163407966	bayes_pls_golite062009
motor activity	2.40267948113603	bayes_pls_golite062009
ATPase activity	2.39535714892224	bayes_pls_golite062009
nucleotide kinase activity	2.24094813695083	bayes_pls_golite062009
glutamate receptor binding	2.18149167417819	bayes_pls_golite062009
phosphotransferase activity, phosphate group as acceptor	1.96697952975573	bayes_pls_golite062009
substrate-specific transporter activity	1.91091452720653	bayes_pls_golite062009
microtubule motor activity	1.77441050776692	bayes_pls_golite062009
hydrolase activity	1.57549510726226	bayes_pls_golite062009
substrate-specific transmembrane transporter activity	1.56325751172863	bayes_pls_golite062009
cytoskeletal protein binding	1.50574672650697	bayes_pls_golite062009
nucleic acid binding	1.08697924060619	bayes_pls_golite062009
catalytic activity	1.00104173493322	bayes_pls_golite062009
guanylate kinase activity	0.98934362137863	bayes_pls_golite062009
ion transmembrane transporter activity	0.977237423302079	bayes_pls_golite062009
signal transducer activity	0.952448314982579	bayes_pls_golite062009
molecular transducer activity	0.952448314982579	bayes_pls_golite062009
purine nucleotide binding	0.929901285538132	bayes_pls_golite062009
nucleotide binding	0.922442819194247	bayes_pls_golite062009
purine ribonucleotide binding	0.920987930180051	bayes_pls_golite062009
ribonucleotide binding	0.920926158369519	bayes_pls_golite062009
peptide-transporting ATPase activity	0.911425383309011	bayes_pls_golite062009
actin binding	0.875514430441177	bayes_pls_golite062009
peptide transporter activity	0.73541731084591	bayes_pls_golite062009
DNA binding	0.702147676354075	bayes_pls_golite062009
cation transmembrane transporter activity	0.557919489256916	bayes_pls_golite062009
anion transmembrane-transporting ATPase activity	0.48775834126327	bayes_pls_golite062009
adenylate kinase activity	0.447752711852745	bayes_pls_golite062009
microfilament motor activity	0.415173945174069	bayes_pls_golite062009
ATP binding	0.41092997612902	bayes_pls_golite062009
adenyl ribonucleotide binding	0.385813421701492	bayes_pls_golite062009
adenyl nucleotide binding	0.377870145186619	bayes_pls_golite062009
transcription regulator activity	0.312171320541728	bayes_pls_golite062009
receptor activity	0.277332279568238	bayes_pls_golite062009
tubulin binding	0.264882086048416	bayes_pls_golite062009
inorganic anion transmembrane transporter activity	0.25714006331445	bayes_pls_golite062009
transmembrane receptor activity	0.243026482777117	bayes_pls_golite062009
proton-transporting ATPase activity, rotational mechanism	0.20818362273204	bayes_pls_golite062009
protein binding	0.170837278876362	bayes_pls_golite062009
microtubule binding	0.156470772916507	bayes_pls_golite062009
inorganic cation transmembrane transporter activity	0.123304946374679	bayes_pls_golite062009
metal ion transmembrane transporter activity	0.0775601177068852	bayes_pls_golite062009
helicase activity	0.0775311459068899	bayes_pls_golite062009

TMHMM	2.0c	PSIPRED	v2.61
SignalP	3.0	COILS	1999
DISOPRED	v0.1	NCBI nr	06/2007
PSI-BLAST	2.2.18	FFAS	ffas03
PDB	06/2007	Pfam	22
HMMER	2.3.2

View Structure Prediction Details

Top Sequence Alignment Hits

Predicted functions: