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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.79364993823]
Complex Size: 2 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ACT1
  • cellular bud neck contractile ring
  • NuA4 histone acetyltransferase complex
  • Swr1 complex
  • Ino80 complex
  • actin filament
  • actin cortical patch
  • histone acetyltransferase complex
  • DNA repair
  • contractile ring contraction involved in cell cycle cytokinesis
  • vesicle transport along actin filament
  • response to osmotic stress
  • cellular cell wall organization
  • cytokinesis
  • endocytosis
  • exocytosis
  • protein secretion
  • chronological cell aging
  • regulation of transcription from RNA polymerase II promoter
  • mitochondrion inheritance
  • ascospore formation
  • vacuole inheritance
  • establishment of mitotic spindle orientation
  • response to oxidative stress
  • budding cell isotropic bud growth
  • histone acetylation
  • actin filament reorganization involved in cell cycle
  • structural constituent of cytoskeleton
  • BNI1
  • polarisome
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • mating projection tip
  • actin filament
  • actin cap
  • intracellular mRNA localization
  • bipolar cellular bud site selection
  • regulation of initiation of mating projection growth
  • response to osmotic stress
  • pseudohyphal growth
  • actin filament organization
  • Rho protein signal transduction
  • budding cell bud growth
  • pheromone-dependent signal transduction involved in conjugation with cellular fusion
  • gene conversion at mating-type locus
  • establishment of mitotic spindle orientation
  • filamentous growth
  • actin nucleation
  • regulation of termination of mating projection growth
  • cytoskeletal regulatory protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    actin filament 1.819E-6 2 9 2 6292
    cortical actin cytoskeleton 6.6999E-5 2 52 2 6292
    cortical cytoskeleton 6.6999E-5 2 52 2 6292
    actin cytoskeleton 1.8038E-4 2 85 2 6292
    cell cortex part 2.304E-4 2 96 2 6292
    cell cortex 2.974E-4 2 109 2 6292
    cellular bud neck 4.1715E-4 2 129 2 6292
    cellular bud 6.9196E-4 2 166 2 6292
    site of polarized growth 7.0879E-4 2 168 2 6292
    cytoskeletal part 1.0156E-3 2 201 2 6292
    cytoskeleton 1.1732E-3 2 216 2 6292
    polarisome 1.9064E-3 2 6 1 6292
    DNA helicase complex 3.4937E-3 2 11 1 6292
    Ino80 complex 3.4937E-3 2 11 1 6292
    actin cap 3.811E-3 2 12 1 6292
    H4/H2A histone acetyltransferase complex 4.4455E-3 2 14 1 6292
    NuA4 histone acetyltransferase complex 4.4455E-3 2 14 1 6292
    Swr1 complex 4.7627E-3 2 15 1 6292
    cellular bud neck contractile ring 5.7138E-3 2 18 1 6292
    actomyosin contractile ring 5.7138E-3 2 18 1 6292
    contractile ring 5.7138E-3 2 18 1 6292
    cell division site part 8.5646E-3 2 27 1 6292
    cell division site 8.5646E-3 2 27 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    spindle localization 2.2737E-6 2 10 2 6292
    establishment of spindle localization 2.2737E-6 2 10 2 6292
    establishment of spindle orientation 2.2737E-6 2 10 2 6292
    establishment of mitotic spindle localization 2.2737E-6 2 10 2 6292
    establishment of mitotic spindle orientation 2.2737E-6 2 10 2 6292
    budding cell bud growth 2.8346E-5 2 34 2 6292
    establishment of organelle localization 7.5032E-5 2 55 2 6292
    actin filament organization 1.151E-4 2 68 2 6292
    response to osmotic stress 1.4784E-4 2 77 2 6292
    cell cycle cytokinesis 1.5966E-4 2 80 2 6292
    establishment of cell polarity 1.7614E-4 2 84 2 6292
    organelle localization 1.8038E-4 2 85 2 6292
    establishment or maintenance of cell polarity 1.8038E-4 2 85 2 6292
    cell budding 2.0236E-4 2 90 2 6292
    asexual reproduction 2.0236E-4 2 90 2 6292
    cytokinetic process 2.1151E-4 2 92 2 6292
    microtubule cytoskeleton organization 2.3525E-4 2 97 2 6292
    microtubule-based process 3.0847E-4 2 111 2 6292
    cytokinesis 3.1407E-4 2 112 2 6292
    actin cytoskeleton organization 3.1973E-4 2 113 2 6292
    actin filament-based process 3.4287E-4 2 117 2 6292
    response to abiotic stimulus 3.4287E-4 2 117 2 6292
    cell morphogenesis 3.9158E-4 2 125 2 6292
    reproductive process in single-celled organism 4.5024E-4 2 134 2 6292
    cellular component morphogenesis 4.7763E-4 2 138 2 6292
    cell division 5.275E-4 2 145 2 6292
    growth 5.275E-4 2 145 2 6292
    cell differentiation 5.4963E-4 2 148 2 6292
    reproductive developmental process 5.7222E-4 2 151 2 6292
    vesicle transport along actin filament 6.3568E-4 2 2 1 6292
    actin filament-based movement 6.3568E-4 2 2 1 6292
    actin nucleation 9.5344E-4 2 3 1 6292
    reproductive cellular process 1.1194E-3 2 211 2 6292
    reproductive process 1.1301E-3 2 212 2 6292
    reproduction of a single-celled organism 1.1841E-3 2 217 2 6292
    vesicle localization 1.2712E-3 2 4 1 6292
    regulation of initiation of mating projection growth 1.2712E-3 2 4 1 6292
    contractile ring contraction involved in cell cycle cytokinesis 1.2712E-3 2 4 1 6292
    cytoskeleton organization 1.3422E-3 2 231 2 6292
    sexual reproduction 1.3656E-3 2 233 2 6292
    actin filament reorganization involved in cell cycle 1.5888E-3 2 5 1 6292
    actin cytoskeleton reorganization 1.5888E-3 2 5 1 6292
    mitotic cell cycle 1.6363E-3 2 255 2 6292
    anatomical structure morphogenesis 1.6621E-3 2 257 2 6292
    anatomical structure development 1.7012E-3 2 260 2 6292
    regulation of termination of mating projection growth 1.9064E-3 2 6 1 6292
    cellular developmental process 1.9175E-3 2 276 2 6292
    regulation of cell projection organization 2.224E-3 2 7 1 6292
    regulation of cell projection assembly 2.224E-3 2 7 1 6292
    regulation of mating projection assembly 2.224E-3 2 7 1 6292
    budding cell isotropic bud growth 2.5415E-3 2 8 1 6292
    reproduction 2.7096E-3 2 328 2 6292
    developmental process 2.7595E-3 2 331 2 6292
    protein secretion 2.859E-3 2 9 1 6292
    regulation of cell morphogenesis 2.859E-3 2 9 1 6292
    mating projection assembly 3.1764E-3 2 10 1 6292
    regulation of response to stimulus 3.1764E-3 2 10 1 6292
    intracellular mRNA localization 3.1764E-3 2 10 1 6292
    cell projection assembly 3.4937E-3 2 11 1 6292
    cell projection organization 3.4937E-3 2 11 1 6292
    regulation of developmental process 3.4937E-3 2 11 1 6292
    gene conversion at mating-type locus 3.4937E-3 2 11 1 6292
    regulation of anatomical structure morphogenesis 3.4937E-3 2 11 1 6292
    cellular response to stimulus 3.6193E-3 2 379 2 6292
    response to chemical stimulus 3.6769E-3 2 382 2 6292
    macromolecule localization 3.9717E-3 2 397 2 6292
    chronological cell aging 4.4455E-3 2 14 1 6292
    vacuole inheritance 4.7627E-3 2 15 1 6292
    mating type switching 5.0798E-3 2 16 1 6292
    cytoskeleton-dependent intracellular transport 5.7138E-3 2 18 1 6292
    regulation of cellular component biogenesis 5.7138E-3 2 18 1 6292
    cell cycle process 6.0534E-3 2 490 2 6292
    response to stress 6.2277E-3 2 497 2 6292
    Rho protein signal transduction 6.3477E-3 2 20 1 6292
    mating type determination 6.3477E-3 2 20 1 6292
    sex determination 6.3477E-3 2 20 1 6292
    cell cycle 6.95E-3 2 525 2 6292
    cell morphogenesis involved in conjugation with cellular fusion 6.9813E-3 2 22 1 6292
    cell fate commitment 7.2981E-3 2 23 1 6292
    cell morphogenesis involved in conjugation 7.6148E-3 2 24 1 6292
    regulation of conjugation with cellular fusion by signal transduction 8.5646E-3 2 27 1 6292
    pheromone-dependent signal transduction involved in conjugation with cellular fusion 8.5646E-3 2 27 1 6292
    DNA metabolic process 8.631E-3 2 585 2 6292
    establishment of localization in cell 9.0494E-3 2 599 2 6292
    mitochondrion distribution 9.1975E-3 2 29 1 6292
    mitochondrion inheritance 9.1975E-3 2 29 1 6292
    mitochondrion localization 9.5139E-3 2 30 1 6292
    G-protein coupled receptor protein signaling pathway 9.8303E-3 2 31 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    cytoskeletal regulatory protein binding 1.9064E-3 2 6 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle