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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 0.894014044307]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chromosomal part 1.413E-3 2 237 2 6292
chromosome 1.8898E-3 2 274 2 6292
origin recognition complex 1.9064E-3 2 6 1 6292
nuclear origin of replication recognition complex 1.9064E-3 2 6 1 6292
pre-replicative complex 5.0798E-3 2 16 1 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication initiation 2.6678E-5 2 33 2 6292
DNA-dependent DNA replication 1.678E-4 2 82 2 6292
DNA replication 3.791E-4 2 123 2 6292
negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
negative regulation of metabolic process 1.1088E-3 2 210 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
negative regulation of DNA replication initiation 2.224E-3 2 7 1 6292
DNA replication checkpoint 2.224E-3 2 7 1 6292
regulation of DNA replication initiation 2.5415E-3 2 8 1 6292
negative regulation of DNA replication 2.859E-3 2 9 1 6292
pre-replicative complex assembly 4.1283E-3 2 13 1 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
leading strand elongation 4.7627E-3 2 15 1 6292
regulation of DNA replication 4.7627E-3 2 15 1 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
lagging strand elongation 5.7138E-3 2 18 1 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
DNA integrity checkpoint 6.3477E-3 2 20 1 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
negative regulation of DNA metabolic process 6.6645E-3 2 21 1 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292
recombinational repair 8.248E-3 2 26 1 6292
mismatch repair 8.5646E-3 2 27 1 6292
DNA metabolic process 8.631E-3 2 585 2 6292
DNA strand elongation 9.8303E-3 2 31 1 6292
DNA strand elongation involved in DNA replication 9.8303E-3 2 31 1 6292
regulation of DNA metabolic process 9.8303E-3 2 31 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

DNA replication origin binding 4.1283E-3 2 13 1 6292

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