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View Protein Complex Details

Complex Overview

From Publication: Qiu J, Noble WS (2008) Predicting Co-Complexed Protein Pairs from Heterogeneous Data. PLoS Comput Biol 4(4): e1000054. doi:10.1371/journal.pcbi.1000054
Notes: Classifier used Gene Ontology annotations. [FDR: 0.02] [SVM Score: 1.04493877044]
Complex Size: 2 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

ESCRT II complex 1.5158E-7 2 3 2 6292
endosomal part 1.2783E-5 2 23 2 6292
endosome membrane 1.2783E-5 2 23 2 6292
endosome 2.2085E-4 2 94 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

negative regulation of transcription by carbon catabolites 1.0611E-6 2 7 2 6292
negative regulation of transcription by glucose 1.0611E-6 2 7 2 6292
negative regulation of transcription from RNA polymerase II promoter by carbon catabolites 1.0611E-6 2 7 2 6292
negative regulation of transcription from RNA polymerase II promoter by glucose 1.0611E-6 2 7 2 6292
regulation of transcription from RNA polymerase II promoter by carbon catabolites 1.0611E-6 2 7 2 6292
regulation of transcription from RNA polymerase II promoter by glucose 1.0611E-6 2 7 2 6292
regulation of transcription by glucose 1.4147E-6 2 8 2 6292
cellular response to nutrient 3.9411E-6 2 13 2 6292
regulation of transcription by carbon catabolites 3.9411E-6 2 13 2 6292
response to nutrient 6.0632E-6 2 16 2 6292
ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway 7.7306E-6 2 18 2 6292
cellular response to external stimulus 3.0063E-5 2 35 2 6292
cellular response to extracellular stimulus 3.0063E-5 2 35 2 6292
cellular response to nutrient levels 3.0063E-5 2 35 2 6292
response to extracellular stimulus 3.552E-5 2 38 2 6292
response to nutrient levels 3.552E-5 2 38 2 6292
response to external stimulus 3.552E-5 2 38 2 6292
cell communication 5.9419E-5 2 49 2 6292
negative regulation of transcription from RNA polymerase II promoter 8.9432E-5 2 60 2 6292
protein targeting to vacuole 1.1854E-4 2 69 2 6292
cellular response to chemical stimulus 2.8654E-4 2 107 2 6292
vacuolar transport 3.312E-4 2 115 2 6292
modification-dependent protein catabolic process 6.1087E-4 2 156 2 6292
ubiquitin-dependent protein catabolic process 6.1087E-4 2 156 2 6292
negative regulation of transcription, DNA-dependent 6.1875E-4 2 157 2 6292
negative regulation of RNA metabolic process 6.2668E-4 2 158 2 6292
proteolysis involved in cellular protein catabolic process 6.3467E-4 2 159 2 6292
modification-dependent macromolecule catabolic process 6.7534E-4 2 164 2 6292
negative regulation of transcription 6.7534E-4 2 164 2 6292
negative regulation of gene expression 6.7534E-4 2 164 2 6292
cellular protein catabolic process 7.3441E-4 2 171 2 6292
negative regulation of macromolecule biosynthetic process 7.6927E-4 2 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 8.1399E-4 2 180 2 6292
negative regulation of nitrogen compound metabolic process 8.1399E-4 2 180 2 6292
proteolysis 8.8816E-4 2 188 2 6292
negative regulation of biosynthetic process 8.9766E-4 2 189 2 6292
negative regulation of cellular biosynthetic process 8.9766E-4 2 189 2 6292
protein catabolic process 8.9766E-4 2 189 2 6292
negative regulation of macromolecule metabolic process 9.2646E-4 2 192 2 6292
negative regulation of cellular metabolic process 1.0983E-3 2 209 2 6292
negative regulation of metabolic process 1.1088E-3 2 210 2 6292
regulation of transcription from RNA polymerase II promoter 1.3075E-3 2 228 2 6292
protein targeting 1.3892E-3 2 235 2 6292
negative regulation of cellular process 1.5726E-3 2 250 2 6292
negative regulation of biological process 1.6107E-3 2 253 2 6292
intracellular protein transport 1.6363E-3 2 255 2 6292
cellular macromolecule catabolic process 1.7674E-3 2 265 2 6292
protein transport 1.8213E-3 2 269 2 6292
establishment of protein localization 1.8485E-3 2 271 2 6292
cellular protein localization 1.8898E-3 2 274 2 6292
cellular macromolecule localization 2.0305E-3 2 284 2 6292
anatomical structure homeostasis 2.0592E-3 2 286 2 6292
telomere organization 2.0592E-3 2 286 2 6292
telomere maintenance 2.0592E-3 2 286 2 6292
macromolecule catabolic process 2.1762E-3 2 294 2 6292
protein localization 2.3118E-3 2 303 2 6292
transcription from RNA polymerase II promoter 2.8267E-3 2 335 2 6292
regulation of transcription, DNA-dependent 3.2288E-3 2 358 2 6292
regulation of RNA metabolic process 3.3198E-3 2 363 2 6292
cellular response to stimulus 3.6193E-3 2 379 2 6292
response to chemical stimulus 3.6769E-3 2 382 2 6292
regulation of transcription 3.7155E-3 2 384 2 6292
macromolecule localization 3.9717E-3 2 397 2 6292
protein localization in Golgi apparatus 4.1283E-3 2 13 1 6292
protein retention in Golgi apparatus 4.1283E-3 2 13 1 6292
homeostatic process 4.1951E-3 2 408 2 6292
regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.3405E-3 2 415 2 6292
cellular catabolic process 4.3405E-3 2 415 2 6292
regulation of nitrogen compound metabolic process 4.3615E-3 2 416 2 6292
regulation of gene expression 4.9915E-3 2 445 2 6292
regulation of macromolecule biosynthetic process 5.2416E-3 2 456 2 6292
regulation of cellular biosynthetic process 5.6164E-3 2 472 2 6292
regulation of biosynthetic process 5.6402E-3 2 473 2 6292
regulation of macromolecule metabolic process 6.004E-3 2 488 2 6292
catabolic process 6.2027E-3 2 496 2 6292
transcription, DNA-dependent 6.3792E-3 2 503 2 6292
RNA biosynthetic process 6.5067E-3 2 508 2 6292
regulation of primary metabolic process 6.6615E-3 2 514 2 6292
regulation of cellular metabolic process 7.2445E-3 2 536 2 6292
regulation of metabolic process 7.5452E-3 2 547 2 6292
regulation of biological quality 7.6561E-3 2 551 2 6292
transcription 7.6839E-3 2 552 2 6292
intracellular transport 7.7118E-3 2 553 2 6292
chromosome organization 7.7677E-3 2 555 2 6292
maintenance of protein location in cell 7.9314E-3 2 25 1 6292
maintenance of protein location 8.248E-3 2 26 1 6292
maintenance of location in cell 8.5646E-3 2 27 1 6292
DNA metabolic process 8.631E-3 2 585 2 6292
maintenance of location 8.8811E-3 2 28 1 6292
establishment of localization in cell 9.0494E-3 2 599 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

regulator of G-protein signaling activity 3.1786E-4 2 1 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle