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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Cdc20. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 8 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

chaperonin-containing T-complex 5.2894E-10 8 12 4 6292
cytosolic part 8.871E-6 8 122 4 6292
cytoskeleton 8.4844E-5 8 216 4 6292
cytosol 2.4634E-4 8 284 4 6292
protein complex 6.5954E-3 8 1137 5 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

protein folding 1.4736E-6 8 78 4 6292
cytoskeleton organization 3.2695E-6 8 231 5 6292
regulation of mitotic metaphase/anaphase transition 4.1826E-4 8 25 2 6292
cellular protein metabolic process 4.9998E-4 8 1074 6 6292
regulation of nuclear division 5.646E-4 8 29 2 6292
regulation of mitosis 5.646E-4 8 29 2 6292
organelle organization 6.5677E-4 8 1127 6 6292
protein metabolic process 6.8696E-4 8 1136 6 6292
mitotic metaphase/anaphase transition 9.2146E-4 8 37 2 6292
regulation of organelle organization 1.8172E-3 8 52 2 6292
activation of mitotic anaphase-promoting complex activity 2.5415E-3 8 2 1 6292
activation of anaphase-promoting complex activity 2.5415E-3 8 2 1 6292
positive regulation of proteasomal ubiquitin-dependent protein catabolic process 2.5415E-3 8 2 1 6292
positive regulation of nuclear division 2.5415E-3 8 2 1 6292
positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 2.5415E-3 8 2 1 6292
positive regulation of mitotic metaphase/anaphase transition 2.5415E-3 8 2 1 6292
positive regulation of mitosis 2.5415E-3 8 2 1 6292
positive regulation of proteolysis 2.5415E-3 8 2 1 6292
regulation of mitotic cell cycle 3.3645E-3 8 71 2 6292
regulation of cellular component organization 3.7475E-3 8 75 2 6292
positive regulation of cellular component organization 3.8101E-3 8 3 1 6292
regulation of proteasomal ubiquitin-dependent protein catabolic process 3.8101E-3 8 3 1 6292
positive regulation of organelle organization 3.8101E-3 8 3 1 6292
positive regulation of ubiquitin-protein ligase activity 3.8101E-3 8 3 1 6292
positive regulation of protein ubiquitination 3.8101E-3 8 3 1 6292
positive regulation of protein catabolic process 3.8101E-3 8 3 1 6292
positive regulation of ligase activity 3.8101E-3 8 3 1 6292
positive regulation of protein modification process 3.8101E-3 8 3 1 6292
cellular component organization 4.336E-3 8 1582 6 6292
regulation of cell cycle process 4.3588E-3 8 81 2 6292
positive regulation of cell cycle process 5.0773E-3 8 4 1 6292
positive regulation of cell cycle 5.0773E-3 8 4 1 6292
malate metabolic process 5.0773E-3 8 4 1 6292
regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle 6.3431E-3 8 5 1 6292
mitosis 7.1004E-3 8 104 2 6292
nuclear division 7.3681E-3 8 106 2 6292
positive regulation of cellular catabolic process 7.6075E-3 8 6 1 6292
regulation of ubiquitin-protein ligase activity 7.6075E-3 8 6 1 6292
regulation of protein ubiquitination 7.6075E-3 8 6 1 6292
regulation of ligase activity 7.6075E-3 8 6 1 6292
organelle fission 8.3409E-3 8 113 2 6292
positive regulation of cellular protein metabolic process 8.8705E-3 8 7 1 6292
positive regulation of catabolic process 8.8705E-3 8 7 1 6292
regulation of protein catabolic process 8.8705E-3 8 7 1 6292
regulation of protein modification process 8.8705E-3 8 7 1 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

unfolded protein binding 5.4385E-7 8 61 4 6292
protein binding 4.508E-3 8 612 4 6292
L-malate dehydrogenase activity 5.0773E-3 8 4 1 6292
MAP kinase kinase activity 5.0773E-3 8 4 1 6292
malate dehydrogenase activity 6.3431E-3 8 5 1 6292
protein serine/threonine/tyrosine kinase activity 8.8705E-3 8 7 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle