YRC Logo
PROTEIN SEARCH:
Descriptions Names[Advanced Search]

Any process that modulates the activity of an enzyme. The process by which one or more ubiquitin moieties are added to a protein. Any process that modulates the frequency, rate or extent of ligase activity, the catalysis of the ligation of two substances with concomitant breaking of a diphosphate linkage, usually in a nucleoside triphosphate. Ligase is the systematic name for any enzyme of EC class 6. Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Any process that modulates the frequency, rate or extent of the covalent alteration of one or more amino acid residues within a protein. Any process that modulates the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Any process that activates, maintains or increases the rate of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine. Any process that modulates the frequency, rate or extent of the addition of ubiquitin moieties to a protein. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity during the meiotic cell cycle. A cell cycle process that modulates the frequency, rate or extent of ubiquitin ligase activity that contributes to the mitotic cell cycle.

View Gene Ontology (GO) Term

GO TERM SUMMARY
Name: regulation of ubiquitin-protein ligase activity
Acc: GO:0051438
Aspect: Biological Process
Desc: Any process that modulates the frequency, rate or extent of ubiquitin ligase activity, the catalysis of the reaction: ATP + ubiquitin + protein lysine = AMP + diphosphate + protein N-ubiquityllysine.
Synonyms:
  • regulation of ubiquitin ligase activity
  • ubiquitin ligase regulator
  • SCF complex regulator
  • anaphase-promoting complex regulator
  • APC regulator
  • ubiquitin-protein ligase regulator
Proteins in PDR annotated with:
   This term: 6 [Search]
   Term or descendants: 119 [Search]


[geneontology.org]
INTERACTIVE GO GRAPH

GO:0051438 - regulation of ubiquitin-protein ligase activity (interactive image map)
YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle