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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Yol087c. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 16 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
ATP3
  • mitochondrial proton-transporting ATP synthase, central stalk
  • mitochondrion
  • ATP synthesis coupled proton transport
  • hydrogen ion transporting ATP synthase activity, rotational mechanism
  • BEM2
  • mitochondrion
  • intracellular
  • small GTPase mediated signal transduction
  • cellular cell wall organization
  • microtubule cytoskeleton organization
  • budding cell bud growth
  • actin cytoskeleton organization
  • Rho GTPase activator activity
  • signal transducer activity
  • COP1
  • COPI vesicle coat
  • ER to Golgi vesicle-mediated transport
  • retrograde vesicle-mediated transport, Golgi to ER
  • molecular_function
  • DUF1
  • cytoplasm
  • biological_process
  • molecular_function
  • EDE1
  • cellular bud tip
  • cellular bud neck
  • actin cortical patch
  • endocytosis
  • ubiquitin binding
  • FOL2
  • nucleus
  • cytoplasm
  • folic acid and derivative biosynthetic process
  • GTP cyclohydrolase I activity
  • HTB2
  • nuclear nucleosome
  • chromatin assembly or disassembly
  • DNA binding
  • LHS1
  • endoplasmic reticulum lumen
  • protein transport
  • response to unfolded protein
  • unfolded protein binding
  • NIP1
  • multi-eIF complex
  • cytoplasm
  • eukaryotic translation initiation factor 3 complex
  • ribosome biogenesis
  • translational initiation
  • translation initiation factor activity
  • POR1
  • integral to mitochondrial outer membrane
  • mitochondrion
  • mitochondrial outer membrane
  • ion transport
  • aerobic respiration
  • mitochondrion organization
  • voltage-gated anion channel activity
  • RPG1
  • incipient cellular bud site
  • cytoplasm
  • ribosome
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • translation initiation factor activity
  • SES1
  • cytoplasm
  • seryl-tRNA aminoacylation
  • serine-tRNA ligase activity
  • SRV2
  • actin cortical patch
  • cytoskeleton organization
  • pseudohyphal growth
  • Ras protein signal transduction
  • adenylate cyclase binding
  • cytoskeletal protein binding
  • TIF34
  • multi-eIF complex
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • translation initiation factor activity
  • TIF35
  • eukaryotic translation initiation factor 3 complex
  • translational initiation
  • translation initiation factor activity
  • UBI4
  • cytoplasm
  • protein deubiquitination
  • ascospore formation
  • protein polyubiquitination
  • protein monoubiquitination
  • response to stress
  • protein ubiquitination
  • protein tag
  • ATP-dependent protein binding
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    eukaryotic translation initiation factor 3 complex 9.7189E-10 16 7 4 6292
    multi-eIF complex 1.6826E-4 16 8 2 6292
    cytoplasm 1.4044E-3 16 3552 15 6292
    actin cortical patch 4.6924E-3 16 41 2 6292
    cortical actin cytoskeleton 7.4654E-3 16 52 2 6292
    cortical cytoskeleton 7.4654E-3 16 52 2 6292
    mitochondrial proton-transporting ATP synthase, central stalk 7.6106E-3 16 3 1 6292
    proton-transporting ATP synthase, central stalk 7.6106E-3 16 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translational initiation 2.9461E-6 16 42 4 6292
    translation 1.8715E-3 16 376 5 6292
    seryl-tRNA aminoacylation 5.0798E-3 16 2 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    translation initiation factor activity 4.7266E-7 16 27 4 6292
    translation factor activity, nucleic acid binding 3.5621E-6 16 44 4 6292
    binding 1.7921E-3 16 1294 9 6292
    GTP cyclohydrolase activity 2.5429E-3 16 1 1 6292
    GTP cyclohydrolase I activity 2.5429E-3 16 1 1 6292
    ATP-dependent protein binding 2.5429E-3 16 1 1 6292
    adenylate cyclase binding 2.5429E-3 16 1 1 6292
    serine-tRNA ligase activity 5.0798E-3 16 2 1 6292
    voltage-gated anion channel activity 7.6106E-3 16 3 1 6292
    anion channel activity 7.6106E-3 16 3 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle