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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Pex7. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 10 proteins

Complex Member Proteins

Protein

GO Cellular Component GO Biological Process GO Molecular Function
CCT2
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • CCT3
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • CCT5
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • CCT6
  • chaperonin-containing T-complex
  • cytoskeleton
  • cytoplasm
  • cytoskeleton organization
  • protein folding
  • unfolded protein binding
  • FZO1
  • mitochondrion
  • mitochondrial outer membrane
  • mitochondrial inner membrane
  • mitochondrial fusion
  • mitochondrion organization
  • GTPase activity
  • MYO2
  • incipient cellular bud site
  • cellular bud tip
  • cellular bud neck
  • fungal-type vacuole membrane
  • myosin V complex
  • mating projection tip
  • vesicle
  • filamentous actin
  • mitochondrion inheritance
  • vacuole inheritance
  • establishment of mitotic spindle orientation
  • unidimensional cell growth
  • vesicle-mediated transport
  • Golgi inheritance
  • vesicle transport along actin filament
  • peroxisome inheritance
  • membrane addition at site of cytokinesis
  • budding cell apical bud growth
  • actin filament binding
  • calmodulin binding
  • microfilament motor activity
  • NEW1
  • cytoplasm
  • mitochondrion
  • ribosome biogenesis
  • ATPase activity
  • ATP binding
  • PEX7
  • cytosol
  • peroxisomal matrix
  • protein targeting to peroxisome
  • peroxisome organization
  • peroxisome matrix targeting signal-2 binding
  • peroxisome targeting sequence binding
  • RPN6
  • proteasome regulatory particle, lid subcomplex
  • ubiquitin-dependent protein catabolic process
  • structural molecule activity
  • UBR1
  • proteasome complex
  • protein polyubiquitination
  • protein monoubiquitination
  • ubiquitin-protein ligase activity
  • Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    chaperonin-containing T-complex 1.5836E-9 10 12 4 6292
    cytoskeleton 9.9692E-6 10 216 5 6292
    cytosolic part 2.5822E-5 10 122 4 6292
    cytosol 3.7818E-5 10 284 5 6292
    protein complex 4.4574E-4 10 1137 7 6292
    proteasome complex 2.4666E-3 10 48 2 6292
    myosin V complex 3.1764E-3 10 2 1 6292
    filamentous actin 3.1764E-3 10 2 1 6292
    unconventional myosin complex 3.1764E-3 10 2 1 6292
    macromolecular complex 4.416E-3 10 1635 7 6292
    myosin complex 4.7611E-3 10 3 1 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    protein folding 4.3382E-6 10 78 4 6292
    cytoskeleton organization 1.3847E-5 10 231 5 6292
    organelle organization 4.2101E-4 10 1127 7 6292
    Golgi inheritance 1.5893E-3 10 1 1 6292
    peroxisome organization 1.8923E-3 10 42 2 6292
    cellular protein metabolic process 2.7454E-3 10 1074 6 6292
    unidimensional cell growth 3.1764E-3 10 2 1 6292
    developmental growth involved in morphogenesis 3.1764E-3 10 2 1 6292
    membrane addition at site of cytokinesis 3.1764E-3 10 2 1 6292
    vesicle transport along actin filament 3.1764E-3 10 2 1 6292
    actin filament-based movement 3.1764E-3 10 2 1 6292
    developmental growth 3.1764E-3 10 2 1 6292
    cellular component organization 3.6048E-3 10 1582 7 6292
    protein metabolic process 3.6994E-3 10 1136 6 6292
    peroxisome inheritance 4.7611E-3 10 3 1 6292
    vesicle localization 6.3436E-3 10 4 1 6292
    Golgi organization 6.3436E-3 10 4 1 6292
    mitochondrial fusion 9.5019E-3 10 6 1 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    P-value

    A

    B

    I

    T

    unfolded protein binding 1.608E-6 10 61 4 6292
    binding 1.0216E-3 10 1294 7 6292
    protein binding 1.4242E-3 10 612 5 6292
    peroxisome matrix targeting signal-2 binding 1.5893E-3 10 1 1 6292
    calmodulin binding 1.5893E-3 10 1 1 6292
    peroxisome targeting sequence binding 4.7611E-3 10 3 1 6292
    microfilament motor activity 7.9239E-3 10 5 1 6292

    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle