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View Protein Complex Details

Complex Overview

From Publication: Ho Y. et al. (2002) Systematic identification of protein complexes in Saccharomyces cerevisiae by mass spectrometry. Nature. 2002 Jan 10;415(6868):180-3.
Notes: This molecular complex record represents a population of complexes co-purified by immunoprecipitation of FLAG-tagged Yen1. The topolgies of protein complexes in this experiment are unknown.
Complex Size: 4 proteins

Complex Member Proteins

Cellular Component Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

PCNA complex 6.3573E-4 4 1 1 6292
chromosomal part 8.0617E-3 4 237 2 6292

Biological Process Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

obsolete_biological_process 5.3002E-4 4 60 2 6292
regulation of histone methylation 6.3573E-4 4 1 1 6292
negative regulation of histone methylation 6.3573E-4 4 1 1 6292
negative regulation of histone modification 6.3573E-4 4 1 1 6292
regulation of histone modification 6.3573E-4 4 1 1 6292
negative regulation of histone H3-K36 methylation 6.3573E-4 4 1 1 6292
regulation of histone H3-K36 methylation 6.3573E-4 4 1 1 6292
protein peptidyl-prolyl isomerization 6.3573E-4 4 1 1 6292
histone peptidyl-prolyl isomerization 6.3573E-4 4 1 1 6292
histone H3-K36 methylation 6.3573E-4 4 1 1 6292
histone lysine methylation 1.2712E-3 4 2 1 6292
regulation of chromosome organization 1.2712E-3 4 2 1 6292
negative regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
gene silencing 1.4697E-3 4 100 2 6292
regulation of gene expression, epigenetic 1.4697E-3 4 100 2 6292
chromatin silencing 1.4697E-3 4 100 2 6292
negative regulation of protein modification process 2.5411E-3 4 4 1 6292
negative regulation of transcription, DNA-dependent 3.5916E-3 4 157 2 6292
negative regulation of RNA metabolic process 3.6369E-3 4 158 2 6292
negative regulation of transcription 3.9142E-3 4 164 2 6292
negative regulation of gene expression 3.9142E-3 4 164 2 6292
regulation of protein modification process 4.4437E-3 4 7 1 6292
negative regulation of macromolecule biosynthetic process 4.4481E-3 4 175 2 6292
negative regulation of nucleobase, nucleoside, nucleotide and nucleic acid metabolic process 4.7016E-3 4 180 2 6292
negative regulation of nitrogen compound metabolic process 4.7016E-3 4 180 2 6292
cellular macromolecular complex assembly 4.8049E-3 4 182 2 6292
negative regulation of biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of cellular biosynthetic process 5.1748E-3 4 189 2 6292
negative regulation of macromolecule metabolic process 5.3374E-3 4 192 2 6292
mutagenesis 5.7106E-3 4 9 1 6292
negative regulation of cellular metabolic process 6.3039E-3 4 209 2 6292
negative regulation of metabolic process 6.3631E-3 4 210 2 6292
base-excision repair 7.6087E-3 4 12 1 6292
negative regulation of cellular process 8.9471E-3 4 250 2 6292
negative regulation of biological process 9.1576E-3 4 253 2 6292
negative regulation of cellular protein metabolic process 9.5041E-3 4 15 1 6292
leading strand elongation 9.5041E-3 4 15 1 6292
cellular macromolecular complex subunit organization 9.5855E-3 4 259 2 6292

Molecular Function Analysis

Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

Only showing terms with a p-value less than or equal to 0.01.

GO Term

P-value

A

B

I

T

7S RNA binding 6.3573E-4 4 1 1 6292
DNA polymerase processivity factor activity 6.3573E-4 4 1 1 6292
5S rRNA binding 1.2712E-3 4 2 1 6292
single-stranded DNA specific endodeoxyribonuclease activity 4.4437E-3 4 7 1 6292
cis-trans isomerase activity 8.8726E-3 4 14 1 6292
peptidyl-prolyl cis-trans isomerase activity 8.8726E-3 4 14 1 6292
histone binding 8.8726E-3 4 14 1 6292

YRC Informatics Platform - Version 3.0
Created and Maintained by: Michael Riffle