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View Protein Complex Details

Complex Overview

From Publication: Krogan N. J. et al. (2006) Global landscape of protein complexes in the yeast Saccharomyces cerevisiae. Nature. 2006 Mar 30;440(7084):637-43. Epub 2006 Mar 22.
Notes: From the published set of core protein complex predictions.
Complex Size: 4 proteins

Complex Member Proteins

Protein

 GO Cellular Component GO Biological Process GO Molecular Function
DPS1
  • cytoplasm
    		•
  • translation
    		•
  • RNA binding
  • aspartate-tRNA ligase activity
    		•
    RAD1
  • nucleotide-excision repair factor 1 complex
  • nucleus
    		•
  • nucleotide-excision repair, DNA incision, 5'-to lesion
  • double-strand break repair via single-strand annealing, removal of nonhomologous ends
  • removal of nonhomologous ends
  • meiotic mismatch repair
  • mitotic recombination
    		•
  • DNA binding
  • single-stranded DNA specific endodeoxyribonuclease activity
    		•
    RAD10
  • nucleotide-excision repair factor 1 complex
  • nucleus
    		•
  • nucleotide-excision repair, DNA incision, 5'-to lesion
  • double-strand break repair via single-strand annealing, removal of nonhomologous ends
  • removal of nonhomologous ends
  • meiotic mismatch repair
  • mitotic recombination
    		•
  • DNA strand annealing activity
  • single-stranded DNA specific endodeoxyribonuclease activity
  • single-stranded DNA binding
    		•
    SAW1
  • nucleus
    		•
  • biological_process
    		•
  • molecular_function
    		•

    Cellular Component Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    nucleotide-excision repair factor 1 complex 9.0929E-7 4 3 2 6292
    nucleotide-excision repair complex 6.3408E-5 4 21 2 6292

    Biological Process Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    double-strand break repair via single-strand annealing, removal of nonhomologous ends 3.0316E-7 4 2 2 6292
    nucleotide-excision repair, DNA incision, 5'-to lesion 3.0316E-7 4 2 2 6292
    nucleotide-excision repair, DNA incision 9.0929E-7 4 3 2 6292
    removal of nonhomologous ends 3.0297E-6 4 5 2 6292
    DNA catabolic process, endonucleolytic 4.5436E-6 4 6 2 6292
    meiotic mismatch repair 1.0898E-5 4 9 2 6292
    double-strand break repair via single-strand annealing 1.0898E-5 4 9 2 6292
    gene conversion at mating-type locus 1.6642E-5 4 11 2 6292
    DNA catabolic process 3.1744E-5 4 15 2 6292
    mating type switching 3.6271E-5 4 16 2 6292
    mating type determination 5.7381E-5 4 20 2 6292
    sex determination 5.7381E-5 4 20 2 6292
    cell fate commitment 7.6359E-5 4 23 2 6292
    mismatch repair 1.0585E-4 4 27 2 6292
    mitotic recombination 1.5902E-4 4 33 2 6292
    non-recombinational repair 1.6892E-4 4 34 2 6292
    nucleotide-excision repair 2.115E-4 4 38 2 6292
    nucleic acid phosphodiester bond hydrolysis 3.1085E-4 4 46 2 6292
    double-strand break repair 4.7822E-4 4 57 2 6292
    meiosis I 9.1886E-4 4 79 2 6292
    DNA recombination 1.9066E-3 4 114 2 6292
    reproductive process in single-celled organism 2.6265E-3 4 134 2 6292
    cell differentiation 3.1966E-3 4 148 2 6292
    reproductive developmental process 3.3258E-3 4 151 2 6292
    M phase of meiotic cell cycle 3.7283E-3 4 160 2 6292
    meiosis 3.7283E-3 4 160 2 6292
    meiotic cell cycle 3.9142E-3 4 164 2 6292
    DNA repair 5.3374E-3 4 192 2 6292
    reproductive cellular process 6.4227E-3 4 211 2 6292
    reproductive process 6.4824E-3 4 212 2 6292
    reproduction of a single-celled organism 6.7852E-3 4 217 2 6292
    response to DNA damage stimulus 7.9954E-3 4 236 2 6292

    Molecular Function Analysis

    Given the number of proteins in the complex (A), total proteins annotated with a given GO term (B), and the total number of annotated proteins (T); the p-value represents the chances of randomly having the number of proteins in the complex annotated with a specific GO term (I).

    Only showing terms with a p-value less than or equal to 0.01.

    GO Term

    		 P-value

    		 A

    		 B

    		 I

    		 T
    single-stranded DNA specific endodeoxyribonuclease activity 6.3596E-6 4 7 2 6292
    endodeoxyribonuclease activity 6.9734E-5 4 22 2 6292
    deoxyribonuclease activity 1.2238E-4 4 29 2 6292
    endonuclease activity 5.4787E-4 4 61 2 6292
    aspartate-tRNA ligase activity 1.2712E-3 4 2 1 6292
    DNA strand annealing activity 2.5411E-3 4 4 1 6292
    nucleic acid binding 4.351E-3 4 666 3 6292
    nuclease activity 5.7261E-3 4 199 2 6292
    DNA binding 9.3704E-3 4 256 2 6292
    YRC Informatics Platform - Version 3.0
    Created and Maintained by: Michael Riffle